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Course Description Course Name : Phase I- Normal Structure and Function/ Cell-Tissue, Human Sciences Course Code : MED100 Course Type : Compulsory Level of Course : First Cycle Year of Study : 1 Course Semester : Fall and Spring (52 Weeks) ECTS : 42 Name of Lecturer(s) : Prof.Dr. ZELİHA NAZAN ALPARSLAN Prof.Dr. HALİL KASAP Prof.Dr. ABDULLAH TULİ Prof.Dr. LEVENT KAYRIN Assoc.Prof.Dr. HAKAN DEMİRHİNDİ Prof.Dr. FERDİ TANIR Prof.Dr. MEHMET AKİF ÇÜRÜK Prof.Dr. İSMAİL GÜNAY Asst.Prof.Dr. ERTAN KARA Prof.Dr. KIYMET AKSOY Prof.Dr. NAFİZ BOZDEMİR Prof.Dr. HÜSNÜ ÜMİT LÜLEYAP Prof.Dr. YUNUS EMRE EVLİCE Assoc.Prof.Dr. NURİ SELİM KADIOĞLU Prof.Dr. FATİH KÖKSAL Prof.Dr. ÖZGÜL TAP Prof.Dr. DAVUT ALPTEKİN Prof.Dr. NURTEN DİKMEN Prof.Dr. MUSTAFA EMRE Prof.Dr. UFUK ÖZGÜ METE Prof.Dr. SAİT POLAT Assoc.Prof.Dr. ERSİN AKPINAR Prof.Dr. OSMAN DEMİRHAN Assoc.Prof.Dr. ESRA SAATÇI Asst.Prof.Dr. BESİM ÖZAYKAN Assoc.Prof.Dr. KEREM TUNCAY ÖZGÜNEN Assoc.Prof.Dr. NESLİHAN BOYAN Prof.Dr. ÖZKAN OĞUZ Assoc.Prof.Dr. EMİNE DÖNDÜ KIZILKANAT Assoc.Prof.Dr. PINAR KARAKAŞ Asst.Prof.Dr. HÜLYAÖZGÜR Prof.Dr. MEMDUHA GÜLHAL BOZKIR Prof.Dr. BEHİCE DURGUN Prof.Dr. İSMAİL SONER KOLTAŞ Prof.Dr. NURGÜL ÖZPOYRAZ Prof.Dr. FÜGEN YARKIN Prof.Dr. MEHMET MACİT İLKİT Prof.Dr. AKGÜN YAMAN Prof.Dr. LUT TAMAM Assoc.Prof.Dr. GONCA KARATAŞ KARAKUŞ Instructor AYKUT PELİT Instructor IŞIL ÖCAL Assoc.Prof.Dr. AYFER PAZARBAŞI Learning Outcomes of the Course : To understand the functions of cell structure; definition of the cell, structural features, the structural components of the cell membrane and internal membrane systems, the membrane signaling, defining the names of the other organelles of the cell, and evaluating the structural features and functions and the interaction of cells. 2. Learning about the structure and function of elements, definitions of basic biochemical terms and biomolecules, explaining the structural and functional properties of these, and evaluating how its being synthesized, and their role in chemical reactions. 3. The genetics explains the structure and functional features of molecules carrying genetic information, interactions with other molecules, synthesis of proteins, hereditary transition models of genetic information, chromosomal features and also it associates hereditary diseases with problems that may consist on chromosomes or on genetic transition. The health and disease concept, determinants of health and disease-causing agents are defined and classified by genetics. A good physician should be able to communicate with patient clearly and placid, should be able to master on occupational skills, also should internalize ethical and professional values on patient-physician communication and medical applications in accordance with his/her physician identify. 4. Learning reproduction of microorganisms, structure of genome, nucleic acid metabolism, using DNA in medicine, the main principles of hereditary, cancer and association between biochemistry, behavioral sciences and genetic sciences 5. Gaining knowledge about the structure and functions of lymphatic and hemopoietic systems, mechanic and electric features of muscles and bones, distribution and alterations of allele frequencies, and their association with evolutionary genetics, host-microorganism relationships, defense system and vaccines Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : Understanding normal development, structure and function of human body and intellect in accordance to all phases of life-time, having information about the interaction between body and intellect, using health concepts in proper ways and knowing how to use these information, learning basic approaches about person-to-person communication and attainment of this ability, appreciating the relation between medical sciences and culture, art and social sciences are all main themes of this course. Course Contents : This course continues 36 weeks and includes understanding of normal structures of human body and their functions at the levels of conceptions such as molecules, cells and tissues. Additionally, this course contains protection of health and ethical notion issues. Also, it contains first steps about attainment education on models. Orientation week, first step communication module, emergency health course and health institutions visits, all are the essential parts of this course. Language of Instruction : Turkish Work Place : Lecture hall and laboratory   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 The opening, The First Step Course and The introduction of departments. 2 Scientific method and biological concepts, The origin and evolution living things, Introduction to Biochemistry, Atomic structure and biochemical bonds, The chemical structure of organic compounds, The basic concepts of public health, Social medicine and history, Preventive medicine, Primary care physician practices, Measurement sensible digits and the SI system, Scaling and function relationship of magnitude, First aid course, Hand washing and gloving skills. 3 Scientific method and biological concepts, The origin and evolution living things, Introduction to Biochemistry, Atomic structure and biochemical bonds, The chemical structure of organic compounds, The basic concepts of public health, Social medicine and history, Preventive medicine, Primary care physician practices, Measurement sensible digits and the SI system, Scaling and function relationship of magnitude, First aid course, Hand washing and gloving skills. Preparatory work for the course Lecture hall and laboratory 4 The objective of a being a physician and a social physician, bimolecular and biochemical methods, the main structure amino acid and proteins, The place of human in ecosystem, The ecologic pyramids and bioenergy, Interaction of human and ecosystem, The modern health concepts, the ability to hand washing and gloves wearing, Biogenesis, The bacteria cells, the fungus cells and fungus, the titration laboratory. Preparatory work for the course Lecture hall and laboratory 5 Cellular macromolecules and fluids, cell theory, cell membranes, organelles, cell skeleton, basic structure of carbohydrates, basic structure of lipids and nucleic acids, the ability of hand washing and wearing gloves, first aid course. Preparatory work for the course Lecture hall and laboratory 6 Diffusion through cell membrane, Basic structure of lipids, integrative approach, diffusion, osmosis, plasmolysis, deplasmolysis, photosynthesis and cellular respiration experiment in plant cells, carbohydrates recognition reactions. Preparatory work for the course Lecture hall and laboratory 7 Vitamins and coenzymes, enzymes, endocytosis, excosystosis, specialization to the cell surface, Cell connections, cell conduction of impulses, catabolism, cell respiration, Energy, Power and metabolic rate, the ability to hand washing and wearing gloves. Preparatory work for the course Lecture hall and laboratory 8 Enzyme kinetics, energy metabolism, oxidation and reduction reactions in biological systems, anabolism, photosynthesis, chemosynthesis, family health relationship. Preparatory work for the course Lecture hall and laboratory 9 I. Term Written Examination Committee 10 Definition of Histology and Cytology, tissue preparation and analysis methods, electron microscopy, mechanical properties of biological solids, accidents and airbags, general analysis of metabolism, control of cell cycle, mitosis and meiosis, division of labor between organelles, the ability to taking blood and serum transfuse. Preparatory work for the course Lecture hall and laboratory 11 Nutrition, trace elements, biological membranes and transport systems, digestion and absorption of carbohydrates, the body composition and body fluids, the laws of diffusion, osmotic transitions, carrier proteins, facilitated diffusion, active transport, homeostatic mechanisms, intercellular communication, Ballistocardiography, Sexual, asexual reproduction, gametogenesis and fertilization, the ability to taking blood and serum transfuse, Laboratory demonstration of proteins, visit the Institution application. Preparatory work for the course Lecture hall and laboratory 12 Glycolysis and control of glycolysis, gluconeogenesis, pentose phosphate pathway, reproductive systems of human male and female, growth and development, Fluids and blood pressure, cells and cellular components, Cell nucleus and cell division, receptors, second messengers and signal transduction, the ability of taking blood and serum transfuse, Laboratory demonstration of Mitosis and enzymes. Preparatory work for the course Lecture hall and laboratory 13 Synthesis of fatty acids, prostaglandins, triglyceride and phospholipid metabolism, structure and biosynthesis of cholesterol, Genetic code and transcription, translation and protein synthesis, mutagens and mutations, the heat transfer mechanisms in body and temperature control, the ability to taking blood and serum transfuse, examination of testis and ovarium, sperm and ovum cells, determination of blood glucose. Preparatory work for the course Lecture hall and laboratory 14 Metabolism of cholesterol and bile acids, lipoprotein metabolism, digestion and absorption of proteins, amino acid metabolism and urea synthesis. DNA repair mechanisms, control of gene expression in prokaryotes and eukaryotes, DNA cloning, DNA library and DNA analysis methods, DNA isolation from tumor and normal tissue, DNA electrophoresis, cholesterol testing, blood sampling and the ability to perform serum transfusion. Preparatory work for the course Lecture hall and laboratory 15 Metabolism of cholesterol and bile acids, lipoprotein amino acid conversion to specific products, integration of metabolism, gene therapy and biotechnology, DNA sequence and genome structure, laboratory work for determination of urea. Preparatory work for the course Lecture hall and laboratory 16 Introduction to microbiology, bacterial genetics, transformation, transduction, conjugation, plasmids, purine-pyrimidine metabolism, the relationship between medicine and history, ability to perform injection. Preparatory work for the course Lecture hall and laboratory 17 II. Term Written Examination Committee 18 Introduction to microbiology, bacterial genetics, transformation, transduction, conjugation, plasmids, purine-pyrimidine metabolism, the relationship between medicine and history, the ability to apply the injection. Preparatory work for the course Lecture hall and laboratory 19 Mendelian inheritance, single gene-related inheritance, Interaction between genes, structure of bacterial cell wall, Production of microorganisms, Introduction of behavioral sciences, definitions and concepts, an overview of the evolution of medicine, origin of medicine and antecedent medical applications, organization of DNA and RNA, determination of blood group, barr body and examination of polytene chromosomes, ability to perform injection. Preparatory work for the course Lecture hall and laboratory 20 DNA metabolism, Multiple allelism and blood groups, Multifactorial inheritance, pleiotropi, mitochondrial inheritance, penetrance, sex-dependent inheritance, linkage of gene analysis, behavior and genetics, neurobiological basis of behavior, Evolution of Western medicine, sterilization, disinfection, ability to perform injection, frog and rat dissection. Preparatory work for the course Lecture hall and laboratory 21 Genome analysis and gene mapping, investigation methods for genetic factors, DNA packaging and chromosome, genetics and metabolism of bacteria, structure of viruses and general characteristics, the proliferation of viruses and methods of diagnosis, biopsychosocial approach, adaptation and stress, psychodynamic basics of behavior: the defense mechanisms I, from Renaissance to XIX. Century and the present day medicine, The currents outside to Western medicine, ability to perform injection. Preparatory work for the course Lecture hall and laboratory 22 Protein synthesis and postsynthesis regulations, nucleic acids use in medicine, Cancer Biochemistry, Xenobiotics, viral interference and interferon, psychodynamic basics of behavior: Defense Mechanisms II, Personality Development, Headlines of Medical history, characteristics and mutations of chromosomes, chromosome obtaining methods, Autosomal disorders , ability to perform injection. Preparatory work for the course Lecture hall and laboratory 23 Gender disorders, chromosome separation, genetics of complex diseases, the genetic basis of antibody diversity, monoclonal antibodies and hybridomas, the genetic basis of differences in TCR, General parasitology, medically important protozoa, helminths and arthropods, examination of human chromosomes, karyotype and pedigree analysis, practical in vitro replication studies, ability to perform injection. Preparatory work for the course Lecture hall and laboratory 24 The genetic basis of the immune response, introduction to anatomy and anatomical terms, general information about the bones and joints, Introduction to Biophysics: system concept and bioenergetics, material transport and resting potential of the cell membrane, wound care skills. Preparatory work for the course Lecture hall and laboratory 25 III. Term Written Examination Committee Preparatory work for the course Lecture hall and laboratory 26 Material transport in the cell membrane and resting potential, Subthreshold events and action potential , functional structure of the nerve cells, general information about muscles and blood vessels, innervations of the organs and formations, Shoulder bones: Bone and joints, Epithelial tissue: Protection and glandular epithelium, connective tissue and biochemistry of collagen, Wound care skills. Preparatory work for the course Lecture hall and laboratory 27 The muscles affecting shoulder joint, axillary and breast, biochemistry of muscles, histology of supportive tissue, connective and fatty tissue, ion balance and the resting membrane potential, Histology laboratory: Epithelial tissue, Anatomy Laboratory: Shoulder bones, the muscles affecting shoulder joint, wound care skills Preparatory work for the course Lecture hall and laboratory 28 Subthreshold events and action potential, Ion channels and HH channel model, histology of supportive tissue, connective and fatty tissue, bones of the forearm and art. Cubiti, muscles of the arm, wrist bones and joints, Functional anatomy of hand, upper extremity nerves and lesions, local potentials, action, Anatomy Laboratory: axillary and breast, arm zone, the bones of the forearm, and art. Cubiti, the muscles of the forearm; Wound Care skill. Preparatory work for the course Lecture hall and laboratory 29 Functional structure of junctions and the general principles of junction transmissions, specialized connective tissue: bone and cartilage, muscle tissue: smooth, striated and cardiac muscle, blood and lymph vessels of the upper extremity, columna vertebralis, vertebral joints, compound action potential, Anatomy Laboratory: Forearm and hand region, upper extremity nerves; Histology Laboratory: Supportive tissue: connective and fatty tissue, wound care skills. Preparatory work for the course Lecture hall and laboratory 30 Muscle tissue: smooth, striated and cardiac muscle, histology of nerve tissue, physiology of skeletal muscle and smooth muscle, Muscular contraction: biomechanical and bioenergetic relationships, bioelectric events in muscles and EMG, factors of columna vertebralis movement , femur joint, Anatomy Laboratory: Upper extremity vessels, columna vertebralis and vertebral joints; Histology laboratory: Tissue of bone and cartilage, wound care skills. Preparatory work for the course Lecture hall and laboratory 31 The muscles affecting femur joint, thigh region femoral triangle, adductor canal, knee joint, Histology of nerve tissue, Biomagnetism, Biophysics applications and Laboratory, Laboratory of Anatomy: The femur joint and gluteal region, thigh region femoral triangle, adductor canal; Histology laboratory: Muscle and nerve tissue. Preparatory work for the course Lecture hall and laboratory 32 Leg, Ankle and the muscles affecting foot movements, blood vessels of lower extremity and lymphatics, nerve lesions and nerves, Biophysics applications and laboratory, Anatomy Laboratory: Leg, Ankle and foot. Preparatory work for the course Lecture hall and laboratory 33 Skin and side formations, walking and posture, Integrated Session, Histology Laboratory: Skin and adverse occurrences; Anatomy Laboratory: Ankle and the muscles affecting foot movements, blood vessels of lower extremity and lymphatics, nerves of lower extremity. Preparatory work for the course Lecture hall and laboratory 34 IV. Term Written Examination Committee 35 Bones of the skull, the neck area, Cancer genetics, Peripheral blood, myeloid organs, Hematopoiesis and hemotopoietic organs, Blood formation, erythrocytes, erythropoiesis, functions of white blood cells, relations with host and microorganism, Introduction to Immunology, Bone: The mechanical and electrical properties, erythrocyte metabolism, Anatomy laboratory: the bones of the skull; Histology laboratory: Peripheral blood, myeloid organs. Preparatory work for the course Lecture hall and laboratory 36 The development of the immune system, humoral immunity, Apoptosis, Biomagnetism, as a social institution and as an applied science of medicine: Medicine and Law; hemoglobin structure, synthesis and evolution, structure of myoglobin, hemoglobin degradation, antigens and microbial antigens, Facial anatomy, Head and neck vessels, lymphatics and nerves, Histology laboratory: Hematopoiesis and hemotopoietic organs; Anatomy laboratory: neck and face. Preparatory work for the course Lecture hall and laboratory 37 The development of the immune system, humoral immunity, Apoptosis, Biomagnetism, as a social institution and as an applied science of medicine: Medicine and Law; hemoglobin structure, synthesis and evolution, structure of myoglobin, hemoglobin degradation, antigens and microbial antigens, Facial anatomy, Head and neck vessels, lymphatics and nerves, Histology laboratory: Hematopoiesis and hemotopoietic organs; Anatomy laboratory: neck and face.. Preparatory work for the course Lecture hall and laboratory 38 Iron metabolism, Biochemistry of hemostasis, genetics of metabolic disorders, Population genetics, Epigenetics, head and neck anatomy of the lymphatic system at the childhood stage, tonsils, palatine, thymus, spleen, Histology of lymphoid organs: the thymus and spleen, electrical current and life safety, Biophysics applications; Laboratory of anatomy: Head and neck vessels, lymphatics and nerves; Biochemistry laboratory: hemoglobin electrophoresis. Preparatory work for the course Lecture hall and laboratory 39 Histology of lenfoid organ: thymus and spleen, Introductory information to medical ethics-1: Definition of ethics, Ethic in philosophy and community life, professional ethic, introductory information of medical ethics -2: Patient-Doctor, Relations of Medicine-Society, Evulation of medical morality, introductory information of medical ethics -3: The main concepts particular to medical ethics, Basic principles of medical ethic, Organs and tissues involved in immune response, Immunoglobulins, Complement system, Antigen-antibody cohesion, Plasma proteins, Cellular immunity, lymphokines and cytokines, Blood types, Platelets, plasma proteins, Evolutionary genetics, histology laboratory: histology of lymphoid organs. Preparatory work for the course Lecture hall and laboratory 40 Cellular and Humoral immunity, Vaccines, Immunoglobulins, cytokines, Hemostasis and fibrinolytic system, integrated meeting, microbiology laboratory: serologic tests; Physiology laboratory: blood withdraw, coagulation and bleeding. Preparatory work for the course Lecture hall and laboratory 41 Physiology laboratory: Erythrocyte counting, hematocrit, blood types; Sedimentation, Hb, Ptz, Osmotic fragility; leukocyte counting and peripheral smear. Preparatory work for the course Lecture hall and laboratory 42 V. Term Written Examination Committee 43 Year-end Final 44 Year-end make up Exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Temel Histoloji. • Davies, A., Blakely, A.G.H., Kidd, C. (2001) “Human Physiology” Churchill Livingstone, Toronto • Editör: Erdoğan CİRELİ, Özel Histoloji (Mikrobiyoloji Çalışmaları Uygulama Kılavuzu) • Editör: Yard.Doç.Dr. Hüseyin AKTUĞ, Genel Histoloji (Pratik föyü) • Freshney,R,I (2003) Culture of Animal Cells Springer-Verlas Berlin Heildelberg New York. • Fundamentals of General, Organik and Biological Chemistry, 2nd ed., J. McMurry, M. E. Castellion, Prantice Hall, 1996, USA • Ganong, W.F., Review of Medical Physiology, 17th Edition,Appleton and Lange, 1995 • Ganong, W.F., Review of Medical Physiology, 21st International Edition, Appleton and Lange, 2003 • Genel Histoloji: Ed. Aktuğ H. E.Ü. Basımevi 2002.  Human Physiology” 8th edition, McGraw-Hill, Inc. New York • Vander, A.J., Sherman, J.H., Luciano, D.S. Human Physiology: The Mechanisms of Body Function. 6th Edition, McGraw-Hill, Inc., 1994. • Zimmermann, H. (1993) “Synaptic transmission” Georg Thieme Verlag/Oxford University Press, Stuttgart. • Marks D, Marks A: Basic Medical Biochemistry, a clinical approach, William and Wilkins, Baltimore,1996. • Murray R.K , Granner D.K Harper’s Biochemistry,24th ed. Prentice Hall Internatıonal,1996,509-522  Alberts B, Johnson A, Lewis J, Raff M, Roberts K, ve Walter P. Molecular Biology of The Cell. Fourth Edition. Garland Science, New York (2002), • Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., Watson, J.D. (1994) “Molecular Biology of THE CELL” Garland Publishing Inc., New York • Anatomi: Arıncı Kaplan, Elhan Alaittin, 1-2. cilt, Güneş Kitabevi, 3. Baskı, Ankara. • Berne, R.M. and Levy, M.N (1983) “Physiology”, The C.V. Mosby Company, St. Luis • Biyokimya Laboratuvar Uygulamaları (Editörler: H. Aydın, F. Girgin) EÜTF, 1998. Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 5 90     Homeworks/Projects/Others 5 10 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Describes the normal human body and mental structure, function and interaction in all stages of life. 5 2 Explains and sequences common physical and mental disorders-diseases’ epidemiology, pathology, symptoms, signs, prognosis, and treatments. 5 3 Has the knowledge of ethical principles and preventive medicine methods about creating conditions for healthy living and disease prevention. 5 4 Defines common diseases in our country by selecting current, reliable diagnostic methods and appropriate pharmacological, physical, nutritional, psychosocial treatment methods. 5 5 Understands, analyzes and evaluates health and illness components, process and result, uses the evidence-based methods and updated information in the treatment of patients. Adopts the principle of making a decision by evaluating prevailing evidence of the patient’s choice, and self-experiences. 5 6 Takes accurate, comprehensive and problem focused anamnesis, with a systematic approach to the individual makes physical examination and mental evaluation, decides by paying respect to patient privacy, secrets, honor, faith, cultural differences, sexual orientation. 5 7 In cases that requires emergency response such as significant function and loss of an organ; offers first aid and basic life support and plans the next process. 5 8 Makes differential diagnosis by approaching holistically to the patient, has the skills and competence of rational diagnosis and treatment planning, information about patient and disease management, as an individual and team member takes responsibility for unexpected circumstances, monitors and embraces the patient. 5 9 Makes Individual, family and community oriented health education, executes the field of work as an individual or as a team member, makes counseling, supervision, expertise, leadership. 5 10 Within the framework of the project which will be conducted, plans, manages the staff development of the team and their education, monitors the process and evaluates, works in partnership with other disciplines. 5 11 Develops a positive attitude towards lifelong learning and behavior, adopts the universal conditions required by the profession of medicine. 5 12 Improves self in cultural, artistic and social fields constantly as well as professional development, plays a part in social responsibility projects with other professional groups. 5 13 Has the ability to communicate intercultural, effectively communicates with patients, coworkers and other parts of the community, and supports ideas and suggestions for solutions with qualitative and quantitative data, transfers verbally and in writing by using Turkish correctly. 5 14 Have the philosophy of science, the limits and the accuracy of the knowledge, validity and reliability of the information, knows how to access information and evaluates information by using critical thinking skills, determines the learning needs and resources related to medicine, directs the learning by using the resources effectively. 5 15 Uses medical informatics and communication technologies along with computer software in required level in the field. 5 16 Understands socio-economic effects of health along with the social and behavioral aspects, by using at least one foreign language European Language Portfolio B1 level monitors information and progress in the field and communicates with colleagues. 5 17 Keeps accurate and reliable records, collects data, analyzes, deciphers epidemic, clinical and laboratory data and acts in accordance with ethical principles in the sharing of the results. 5 18 Bears susceptibility and responsibility in the subject of self-mental and physical health, workers´ health, labor and environment safety, individual and public health, becomes role model to society by developing professional attitude. 5 19 Knows the basic health care legislation, as an individual acts in accordance with regulations, laws, legislations and ethical rules about rights and responsibilities. 5 20 Uses professional autonomy, has sufficient experience to carry out preventive medicine service and capable of doing clinical applications in national and international standards. 5 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 32 20 640     Out of Class Study (Preliminary Work, Practice) 32 10 320 Assesment Related Works     Homeworks, Projects, Others 5 5 25     Mid-term Exams (Written, Oral, etc.) 5 8 40     Final Exam 1 30 30 Total Workload: 1055 Total Workload / 25 (h): 42.2 ECTS Credit: 42