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Course Description Course Name : Principles of Medical Biology Course Code : BİO501 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall (16 Weeks) ECTS : 6 Name of Lecturer(s) : Prof.Dr. DAVUT ALPTEKİN Prof.Dr. HALİL KASAP Prof.Dr. MÜLKİYE KASAP Prof.Dr. OSMAN DEMİRHAN Assoc.Prof.Dr. AYFER PAZARBAŞI Prof.Dr. HÜSNÜ ÜMİT LÜLEYAP Learning Outcomes of the Course : Knows the evolution and formation of the cell. Knows the organic components of the cell. Knows the concept of prokaryotic and eukaryotic cells. Knows protista and fungi filum. Knows the cell structure and cell organelles. Knows the structure of genetic material (DNA, RNA). Knows cell cycle, cell division (mitosis and meiosis). Knows animal tissues and recognizes them at the microscope. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : Medical Biology mainly provides the required information about cell biology, evolution of cell, structure of cell, function of cell organelles, structure and significance of genetic materials, tissues formed via cell differentiation and hereditary diseases due to mutations. Course Contents : Methods and Concepts in Biology, Use and Types of Microscope, Origin and Evolution of the living organisms, Molecular Evolution of Human Being, Status of the human in ecosystem, Ecological Pyramids and Bioenergy, Human Environment Interaction, Viruses and Monera, Protista and Fungi, Biological Reactions, Biological Macromolecules and Liquids, Cell Theory and biological membranes, Cell organelles, Moving the Cell Membrane, Cell surface specializations and Connections, Cell Communication Systems, photosynthesis and chemosynthesis, cellular respiration, Cell Cycle, Cell Division and Control, Asexual and sexual reproduction, Tissues. Language of Instruction : Turkish Work Place : Seminar room   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Methods and Concepts in Biology Use and Types of Microscope Standard classroom technologies, multimedia tools, projector, computer Lesson, Discussion. 2 Origin and Evolution of the creature Molecular Evolution of Man Standard classroom technologies, multimedia tools, projector, computer Lesson, Discussion. 3 Molecular Evolution of Man Place of the human in the ecosystem Standard classroom technologies, multimedia tools, projector, computer Lesson, Discussion. 4 Ecological Pyramids and Bioenergy Human Environment Interaction Standard classroom technologies, multimedia tools, projector, computer Lesson, Discussion. 5 Viruses and Monera Protista and Fungi Standard classroom technologies, multimedia tools, projectors, computers, microscopes Lesson, Discussion, Demostration. 6 Biological Reactions Biological Macromolecules and Liquids Standard classroom technologies, multimedia tools, projector, computer Lesson, Discussion. 7 Cell Theory and biological membranes Cell organelles Standard classroom technologies, multimedia tools, projectors, computers, microscopes Lesson, Discussion, Demostration. 8 Cell organelles Standard classroom technologies, multimedia tools, projectors, computers, microscopes Lesson, Discussion, Demostration. 9 Moving the Cell Membrane Cell surface specializations and Connections Standard classroom technologies, multimedia tools, projector, computer Lesson, Discussion. 10 Cell Communication Systems Photosynthesis and chemosynthesis Standard classroom technologies, multimedia tools, projector, computer Lesson, Discussion. 11 Cell Respiration Cell Cycle, Cell Division and Control Standard classroom technologies, multimedia tools, projector, computer Lesson, Discussion. 12 Cell Cycle, Cell Division and Control Asexual and sexual reproduction Standard classroom technologies, multimedia tools, projectors, computers, microscopes Lesson, Discussion, Demostration. 13 Gametogenesis, fertilization and Phases of the zygote division, Postembryonic Development and Morphogenesis Standard classroom technologies, multimedia tools, projector, computer Lesson, Discussion. 14 Tissues Standard classroom technologies, multimedia tools, projectors, computers, microscopes Lesson, Discussion, Demostration. 15 Midterm exam Classroom Testing and evaluation with multiple choice questions. 16/17 Final exam Classroom Testing and evaluation with multiple choice questions.   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Klug WS, Cummings MR. Genetic Concepts, Sixth Edition. Editor; Öner C., Palme yayıncılık, 2002.  Cooper GM, Hausman RE. The Cell, Molecular Aproach. Third Edition. Editors: Meral sakızlı, Neşe Atabey. İzmir Tıp Kitabevi, 2006.  Kasap H, Kasap M, Demirhan O, Alptekin D, Lüleyap Ü, Pazarbaşı A, Güzel Aİ. Medical Biology and Genetics. Editör: Halil Kasap, Nobel Tıp Kitabevi, Adana, 2010. Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 50     Homeworks/Projects/Others 2 50 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Explains theorical debates of three main areas (philosophy, sociology, psychology) in relation to today´s problems 5 2 Knows the functions of tissues and organ systems. 3 3 Knows the structure of the genetic material. 5 4 Knows the genetic diseases and the genes that cause genetic diseases and disorders. 3 5 Is able to conduct molecular and cytogenetic diagnosis analysis. 2 6 Knows what numerical and structural abnormalities of the autosomes and the sex chromosomes mean and explain them. 0 7 Is able to do DNA isolation from all types of tissue. 3 8 Is able to perform PCR. 3 9 Is able to perform and interpret agarose and polyacrylamide gel electrophoresis. 3 10 Is able to measure the DNA obtained from tissues using a spectrophotometer. 4 11 Is capable of interpreting and implementing QF-PCR technique. 0 12 Is able to cell culture from blood, amniotic, chorionic villus biopsy specimens, and obtain chromosome preparation. 1 13 Is able to recognize and interpret all human chromosomes from the preparations derived from chromosome karyotype analysis. 3 14 Learns how to write and comment on a scientific article. 1 15 Knows the structure of genes. 3 16 Knows the chromosome and gene mutations. 2 17 Knows patterns of inheritance (autosomal dominant, autosomal recessive, sex-linked dominant and recessive inheritance models). 2 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 4 56     Out of Class Study (Preliminary Work, Practice) 14 6 84 Assesment Related Works     Homeworks, Projects, Others 2 5 10     Mid-term Exams (Written, Oral, etc.) 1 1 1     Final Exam 1 1 1 Total Workload: 152 Total Workload / 25 (h): 6.08 ECTS Credit: 6