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Course Description Course Name : Antibiotics And Their Influence Mechanisms Course Code : BL 448 Course Type : Optional Level of Course : First Cycle Year of Study : 4 Course Semester : Spring (16 Weeks) ECTS : 4 Name of Lecturer(s) : Prof.Dr. HATİCE KORKMAZ GÜVENMEZ Learning Outcomes of the Course : Have enough information about the effects of antimicrobial agents and resistance mechanisms of microorganisms . Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : BL 448 Antibiotics And Their Influence Mechanisms Recommended Optional Programme Components : None Aim(s) of Course : Teaching the Influence of chemical and biological antimicrobial agents on micro-organisms, microorganisms have developed mechanisms of resistance to these agents behaviors Course Contents : Chemical antimicrobial agents, control of microbial growth Antibiotics targets Synthetic antimicrobial drugs Natural antimicrobial drugs: Antibiotics The antibiotics of inhibiting of cell wall synthesis: Penicillins, cephalosporins, bacitracins, carbapenem, monobactam, vancomycine The antibiotics of inhibiting of protein synthesis: Macrolids, aminoglycozides, tetracyclins, lincosamide DNA-gyrase inhibitors; quinolons Lipid biosynthesis inhibitors, antimicrobial agents on folic acid metabolism antimicrobial agents on sytoplasmic membrane structure and function: polymyxines, daptomycine antiviral agents antifungal agents antiparasiter agents Language of Instruction : Turkish Work Place : clasrroom   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 chemical antimicrobial agents, the control of microbial growth. reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 2 The pathway of using in vivo in organism of an antimicrobial agent reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 3 Places and ways of application of antimicrobial agents. reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 4 targets of antibiotics reading current lecture notes, related papers,and searching internetreading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 5 synthetic antimicrobial drugs reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 6 natural antimicrobial drugs: Antibiotics reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 7 Cell wal synthesis inhibitors: Penicilline, cephalosporins, bacitracins, carbapenems, monobactam, vancomycine reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 8 Mid-term exam 9 Protein synthesis inhibitors: macrolida, aminoglycoside, tetracycline, lincozamids reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussiontelling with lecture notes and projection and interactive discussion 10 DNA-gyrase inhibitors: Quinolons reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 11 Lipid biosynthesis inhibitors, reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 12 folic acid metabolism effective antimicrobial agents reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 13 antiviral agents reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 14 antifungal agents reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 15 antiparasiter agents reading current lecture notes, related papers,and searching internet telling with lecture notes and projection and interactive discussion 16/17 final exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  What is an Antibiotic?, 2003. R. Bentley, J.W. Bennett.  . Pharmacology, 1998. P. Winstanley, T. Walley.  Brock Biology of Microorganism, 2009. M.T. Madigan, J.M. Martinko, P.V.Dunlap, D.P.Clark Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 95     Homeworks/Projects/Others 2 5 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Explains the methods of producing scientific knowledge in the field of biology 0 2 Uses the advanced theoretical and practical knowledge acquired in the field of biology 0 3 Develops his/her professional experiences and knowledges by taking elective courses together with basic subjects of biology 5 4 takes responsibility as an individual or in a group to solve unpredicted problems that would be encountered 4 5 plans and manages the projects as a member of team 1 6 informs an indivudual and institutions about the subjects related to biology, and prepare verbal and written presentation to solve the problems 5 7 communicates effectively with colleagues in the world about biological issues and works 1 8 Knows the importance of individual development 0 9 Reaches the Information in the field of physics, for the purpose of classification, and uses. 0 10 Knows that learning process is life-long and acts accordingly. 0 11 Evaluates the developmets in the field of biology by using scientific methods 0 12 Explains the basic concepts and principles in the field of biology 0 13 Combines the knowledge in the field of biology with the other scientific area. 0 14 Both with colleagues, as well as off the field of builds establish relations ethically and uses information, communication technologies. Defines necessities in learning in scientific, social, cultural and artistic areas and improves himself/herself accordingly. 0 15 Identifies problems in the field of biology and for the solutions apply the analytical and simulative methods. 0 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 2 28     Out of Class Study (Preliminary Work, Practice) 14 2 28 Assesment Related Works     Homeworks, Projects, Others 2 5 10     Mid-term Exams (Written, Oral, etc.) 1 10 10     Final Exam 1 15 15 Total Workload: 91 Total Workload / 25 (h): 3.64 ECTS Credit: 4