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Course Description Course Name : Blood Banking and Transfusion Medicine II Course Code : PH-511 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 1 Course Semester : Spring (16 Weeks) ECTS : 5 Name of Lecturer(s) : Learning Outcomes of the Course : A student learns blood groups. A student can operate antiglobulin tests, blood transfusion reactions. A student learns apheresis techniques and can operate them. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : When students finish the" Blood Banking and Transfusion Medicine II" Course, they will recognize and be able to apply laboratory tests and make comments about platelet transfusion and side effects, thrombocytapheresis, diseases transferring with blood, the principles of stem cell therapy, therapeutic plasma exchange and indications, erythrocytapheresis, leucocytapheresis, the apheresis indications in pediatric age groups, cell transfusions originated from peripheral or bone marrow stem cells. Course Contents : Platelet transfusion: criteria, dosage, clinical indications, occurence of platelet alloantibodies and prevention methods, the complications of platelet transfusion,the infection transmitted by blood transfusion, graft-versus-host reaction, stem and progenitor cells, hemopoetic engrafment, gene marking and gene therapy, dosages and treatment regimes, toxicity, therapeutic plasma exchange and cytapheresis, manual and automatized apheresis, erythrocytapheresis, leucocytapheresis,photopheresis, the indications of plasma exchange, preparation and applications, preparation of stem cells originated from peripheral blood or bone marrow. Language of Instruction : Turkish Work Place : The Seminar Halls of Pediatric Hematology, Blood Banking Unit and Apheresis Section, Pediatric Stem Cell Transplantation Laboratories.   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Thrombocyte transfusion:Clinical indications Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 2 Prevention methods of platelet alloantibodies. Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 3 The Complication of Platelet Transfusion Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 4 Infections communicable with platelet transfusions Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 5 Transfusion Reactions:GVHD Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 6 Manual and automatized apheresis Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 7 The Principles of Pediatric Apheresis Practice andLaboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 8 Erythrocytapheresis, leucocytapheresis, photopheresis Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 9 Plasma exchange:indications, preparation and practice. Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 10 Stem Cell Transplant originating from the Bone Marrow and Peripheral Blood Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 11 Progenitor Stem Cells Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 12 Progenitor Stem Cells and Hematopoietic Engrafment. Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 13 Genes and Marking Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 14 Gene Therapy Practice and Laboratory Work Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 15 Seminar Study from the sources, searching for the literature Instruction, seminar, group discussion, brainstorming. 16/17 Final Exam Revise the sources Written and oral exams   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Wintrobe’s Clinical Hematology:Greer JP, Foerster J, Lukens JN, Rodgers GM, Paraskaras F, Glader B(eds), Vol 1 and 2, 11th ed, Lippincott Williams and Wilkins, Philadelphia, 2004 Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 90     Homeworks/Projects/Others 2 10 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 A student can perform laboratory techniques. 4 2 A student can communicate and create bonds with the patients. 3 3 A student can teach the bone marrow stromal and medullary componants which are basic components of hematology. 4 4 A student can describe the rules of basic hematology. 4 5 A student can become trained in the area of molecular changes in benign and malign hematological disorders. 3 6 A students acknowledges blood cells biologies, blood and blood components transfusion and stem cell transplantation procedures. 4 7 A student gets prepared for stem cell transplant, collection, seperation, freezing topics. 4 8 A student can explain the structure and functions of erythrocytes, leucocytes and platelets. 4 9 A student can work in a pediatric hematology laboratory. 4 10 A student gets prepared for basic rules of gene therapy. 4 11 A student can investigate the molecular basis of benign and malign hematological disorders. 4 12 A student can explain the physiopathologies and results of hemostasis and thrombosis. 4 13 A student becomes competent in the application areas of blood cells and components and bone marrow transplantation 4 14 A student can perform application of the laboratory techniques necessary for pediatric hematology. 4 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 4 56     Out of Class Study (Preliminary Work, Practice) 14 1 14 Assesment Related Works     Homeworks, Projects, Others 2 20 40     Mid-term Exams (Written, Oral, etc.) 1 10 10     Final Exam 1 10 10 Total Workload: 130 Total Workload / 25 (h): 5.2 ECTS Credit: 5