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Course Description Course Name : Entrance to the Basic Hematology II Course Code : PH-501 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 1 Course Semester : Spring (16 Weeks) ECTS : 5 Name of Lecturer(s) : Prof.Dr. YURDANUR KILINÇ Learning Outcomes of the Course : A student learns the normal morphologies and disorders of red blood cells, leucocytes, lymphocytes and monocytes. A student learns normal laboratory range of parameters, and can report potential differences. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : When students finish the Introduction to the Basic Hematology II Course, they will recognize the endothelal physiology and disorders, hemostasis and thrombosis, platelet disorders, leucocytes and leucocyte immunology, and they will discriminate the physiological and pathological states. Course Contents : Endothelium, vascular hemostasis disorders and bleeding tendencies, the laboratory evaluation of hemophilias, quantitative and qualitative disorders of platelets-laboratory diagnosis, hemostasis and thrombosis, thrombophylias, thrombosis risk factorsa and laboratory evaluation, qualitative and quantitative disorders of leucocytes, leukemias and laboratory diagnosis, flow-cytometric tools, cellular and humoral immune deficiencies. Language of Instruction : Turkish Work Place : Seminar Halls of the Department of Pediatric Hematology and Laboratories of Pediatric Hematology.   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Description , classification and Laboratory evaluation of anemias. Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 2 Description of microcytic and macrocytic anemias and laboratory diagnosis Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 3 Iron metabolism:laboratory evaluation , iron deficiency anemia. Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 4 Sideroblastic anemias;laboratory diagnostic tools. Practise and Laboratory Work. Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 5 Anemias of Chronic Diseases and Hemochromatosis;Laboratory diagnosis. Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 6 N ormochromic-normositer anemias:diagnosis, classification and laboratory. Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 7 Hemolytic anemias:Classification, laboratory approach and evaluation. Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 8 Hereditary Hemolytic Anemias:Laboratory diagnostic methods. Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 9 Erythrocytic Enzyme Defects:Laboratory Diagnosis and Evaluation. Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 10 Glucose-6-phosphate Dehydrogenase Deficiency: Classification and Laboratory diagnosis. Practice and Laboıratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 11 Hemoglobinopathies:Classification, laboratory approach and evaluation Practice and Laboıratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 12 Immune Hemolytic Anemias:Laboratory Diagnosis Methods Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 13 Hemostasis and Coagulation:Laboratory Diagnosis and Evaluation Practice and Laboratory Evaluation Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 14 Make-up Lesson Practice and Laboratory Work Reading the adviced sources, seminar, practice Instruction, presentation, group discussion, brainstorming, seminar, exercise 15 Semiannual Seminar Kaynakları okuma, hazılanma, Instruction, presentation, group discussion, brainstorming, seminar, exercise 16/17 Final Exam Kaynakları okuma, hazılanma, Written and oral exams   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Hematology:Clinical and Laboratory Practice. Bick RL, Vol 1 ve 2, CV Mosby Company, St. Louise, 1993.  Wintrobe’s Clinical Hematology:Greer JP, Foerster J, Lukens JN, Rodgers GM, Paraskaras FGlader B(eds), Vol 1 and 2, 11th ed, Lippincott Williams and Wilkins, Philadelphia, 2004. Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 90     Homeworks/Projects/Others 2 10 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 A student can perform laboratory techniques. 4 2 A student can communicate and create bonds with the patients. 4 3 A student can teach the bone marrow stromal and medullary componants which are basic components of hematology. 4 4 A student can describe the rules of basic hematology. 5 5 A student can become trained in the area of molecular changes in benign and malign hematological disorders. 4 6 A students acknowledges blood cells biologies, blood and blood components transfusion and stem cell transplantation procedures. 3 7 A student gets prepared for stem cell transplant, collection, seperation, freezing topics. 4 8 A student can explain the structure and functions of erythrocytes, leucocytes and platelets. 5 9 A student can work in a pediatric hematology laboratory. 5 10 A student gets prepared for basic rules of gene therapy. 5 11 A student can investigate the molecular basis of benign and malign hematological disorders. 4 12 A student can explain the physiopathologies and results of hemostasis and thrombosis. 4 13 A student becomes competent in the application areas of blood cells and components and bone marrow transplantation 4 14 A student can perform application of the laboratory techniques necessary for pediatric hematology. 4 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 4 56     Out of Class Study (Preliminary Work, Practice) 14 1 14 Assesment Related Works     Homeworks, Projects, Others 2 20 40     Mid-term Exams (Written, Oral, etc.) 1 10 10     Final Exam 1 10 10 Total Workload: 130 Total Workload / 25 (h): 5.2 ECTS Credit: 5