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Course Description Course Name : Molecular Pathology of Childhood Cancers Course Code : PEDO-528 Course Type : Optional Level of Course : Second Cycle Year of Study : 1 Course Semester : Spring (16 Weeks) ECTS : 5 Name of Lecturer(s) : Prof.Dr. MELEK ERGİN Learning Outcomes of the Course : A student learns the molecular basis of cancer. A student learns the formation of malign transformation. A student gains knowledge about the molecular changes in cancer cases. A student gains knowledge and skills on molecular techniques. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : PEDO-522 Molecular Basis of Childhood Cancers Recommended Optional Programme Components : None Aim(s) of Course : Students learn the basic principles of molecular biology, cancer genetics, nucleid acid biology, and the principles of nucleid acid technologies. Course Contents : Background information, cancer pathology, tumor surpressor genes, malign transformation, molecular techniques, prognostic factors. Language of Instruction : Turkish Work Place : Classroom   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Childhood tumors 1 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 2 Childhood tumors 2 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 3 Essential changes in malign transformation 1 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 4 Essential changes in malign transformation 2 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 5 Oncogenes Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 6 Tumor surpressor genes 1 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 7 Tumor surpressor genes 2 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 8 Mid-term exam Revision Written exam 9 Changes in pediatric molecular solid tumors 1 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 10 Changes in pediatric molecular solid tumors 2 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 11 Diagnosis principles Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 12 Molecular techniques 1 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 13 Molecular techniques 2 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 14 Prognostic factors 1 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 15 Prognostic factors 2 Studying related chapters in the course books and literature in the field Audiovisual presentation, discussion and brainstorming. 16/17 Final Exam General Revision Written exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  1-Pathologic Basis of Disease 2- Cell and Tissue based Molecular pathology Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 8 50     Homeworks/Projects/Others 15 50 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 A student can explain the basic concepts and principles of bone marrow transplantation 2 2 A student can explain the basic principles of tumor immunology 3 3 A student can explain the basic principles of oncogenesis and its molecular basis 4 4 A student can explain the basic principles of pediatric oncology 1 5 A student can explain the basic principles of tumor biology 5 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 3 42     Out of Class Study (Preliminary Work, Practice) 10 2 20 Assesment Related Works     Homeworks, Projects, Others 15 2 30     Mid-term Exams (Written, Oral, etc.) 8 2 16     Final Exam 8 2 16 Total Workload: 124 Total Workload / 25 (h): 4.96 ECTS Credit: 5