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Course Description Course Name : Bone Marrow and Stem Cell Transplantation Course Code : PEDO-512 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall (16 Weeks) ECTS : 4 Name of Lecturer(s) : Asst.Prof.Dr. GÜLAYSEZGİN Learning Outcomes of the Course : A student understands what a stem cell is and differentiates various sources of stem cells A student gets insight into different types of transplant and indications for transplant A student can select and prepare patients for transplant A student can monitor and manage post-transplant complications. A student can manage late complications of transplant A student can perform post-transplant immunization Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : PEDO-504 Functions of the Reticuloendothelial System PEDO-518 Bone Marrow Immunology and Laboratory Recommended Optional Programme Components : PEDO516,PEDO518,PEDO508,PEDO514,PEDO530 Aim(s) of Course : Students get insight into different sources of stem cells and types of stem cell transplantation Course Contents : Preparation of the patient to stem cell transplantation,follow up operations and monitoring and managing complications of transplant Language of Instruction : Turkish Work Place : Lectures will be held in the classroom and also patient bedside   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 What is a stem cell? Reading relevant articles and book chapters Lecture and Interactive discussion 2 Sources of stem cells Reading relevant articles and book chapters Lecture and Interactive discussion 3 Patient selection Reading relevant articles and book chapters Bedside applied instruction 4 Patient preparation for the transplant Reading relevant articles and book chapters Bedside applied instruction 5 Infection prophylaxis Reading relevant articles and book chapters Lecture and Interactive discussion 6 Graft versus host prophylaxis Reading relevant articles and book chapters Lecture and Interactive discussion 7 Conditioning regimens Reading relevant articles and book chapters Lecture and Interactive discussion 8 Mid-term exam Revision Written and applied exam 9 Infectious complications after transplantation Reading relevant articles and book chapters Lecture and Interactive discussion 10 Patient follow-up after transplant Reading relevant articles and book chapters Bedside applied instruction 11 Post-transplant complications Reading relevant articles and book chapters Lecture and Interactive discussion 12 Acute graft versus host disease Reading relevant articles and book chapters Lecture and Interactive discussion 13 Chronic graft versus host disease Reading relevant articles and book chapters Lecture and Interactive discussion 14 Post-transplant immunization of the patient Reading relevant articles and book chapters Lecture and Interactive discussion 15 Late effects of stem cell transplantation Reading relevant articles and book chapters Lecture and Interactive discussion 16/17 Final exam Revision of all topics Written and applied exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Thomas´ Hematopoietic Cell transplantation 4th Ed  Hematopoietic Stem Cell Transplantation in Clinical Practice Jennifer Treleaven A.John Barrett Required Course Material(s)  American Society for Blood and Marrow Transplantation www.asbmt.org  The European Society for Bone Marrow Transplantation www.ebmt.org   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 8 50     Homeworks/Projects/Others 15 50 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 A student can explain the basic concepts and principles of bone marrow transplantation 5 2 A student can explain the basic principles of tumor immunology 2 3 A student can explain the basic principles of oncogenesis and its molecular basis 3 4 A student can explain the basic principles of pediatric oncology 1 5 A student can explain the basic principles of tumor biology 1 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 2 28     Out of Class Study (Preliminary Work, Practice) 10 2 20 Assesment Related Works     Homeworks, Projects, Others 15 2 30     Mid-term Exams (Written, Oral, etc.) 8 2 16     Final Exam 8 2 16 Total Workload: 110 Total Workload / 25 (h): 4.4 ECTS Credit: 4