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| Course Description |
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| Course Name |
: |
Radiobiology and Biophysics for Medical Physicists |
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| Course Code |
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MEDF-503 |
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| Course Type |
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Compulsory |
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| Level of Course |
: |
Second Cycle |
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| Year of Study |
: |
1 |
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| Course Semester |
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Fall (16 Weeks) |
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| ECTS |
: |
4 |
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| Name of Lecturer(s) |
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Prof.Dr. İSMAİL GÜNAY
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| Learning Outcomes of the Course |
: |
Learns the types of radiation
discusses the effects of ionize and nonionize radiations
knows the importance of molecular bonding and bond energy
Understands the fundamental principles of radiobiology
learns molecular radiobiology
Comprehends the deterministic effects of radiation
Comprehends the stochastic effects of radiation
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| Mode of Delivery |
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Face-to-Face |
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| Prerequisites and Co-Prerequisites |
: |
None |
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| Recommended Optional Programme Components |
: |
None |
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| Aim(s) of Course |
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The aim of this course is to explain and teach the interaction of biological material with ionize radiation ,and also dose-response relations under the effects of radiation with numerical samples |
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| Course Contents |
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Fundamental concepts of radiologic science, structure of matter and atoms, molecular bonding and bonding energy, electromagnetic energy and ionization, human biology, fundamental principle of radiobiology, molecular radiobiology, cellular radiobiology, deterministic effects of radiation, stochastic effects of radiation, homework1,2,3,4 |
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| Language of Instruction |
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Turkish |
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| Work Place |
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classroom |
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Course Outline /Schedule (Weekly) Planned Learning Activities |
| Week | Subject | Student's Preliminary Work | Learning Activities and Teaching Methods |
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1 |
Fundamental concepts of radiologic science |
Student previously reads the related chapter |
Lecture by teacher, class discussion, recitation, open textbook tests, take home tests |
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2 |
Structure of matter and atoms |
Student previously reads the related chapter |
Lecture by teacher, class discussion, recitation, open textbook tests, take home tests |
|
3 |
Molecular bonding and bond energy |
Student previously reads the related chapter |
Lecture by teacher, class discussion, recitation, open textbook tests, take home tests |
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4 |
Electromagnetic energy and ionization |
Student previously reads the related chapter |
Lecture by teacher, class discussion, recitation, open textbook tests, take home tests |
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5 |
Human biology |
Student previously reads the related chapter |
Lecture by teacher, class discussion, recitation, open textbook tests, take home tests |
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6 |
Human biology |
Student previously reads the related chapter |
Lecture by teacher, class discussion, recitation, open textbook tests, take home tests |
|
7 |
Fundamental principles of radiobiology |
student previously reads the related chapter |
Lecture by teacher, class discussion, recitation, open textbook tests, take home tests |
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8 |
Molecular radiobiology |
student previously reads the related chapter |
Lecture by teacher, class discussion, recitation, open textbook tests, take home tests |
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9 |
assignment 1 |
student reads the related chapter from textbook and literature |
recitation by the student and class discussion |
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10 |
Cellular radiobiology |
student previously reads the related chapter |
Lecture by teacher, class discussion, exercise |
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11 |
assignment 2 |
student reads the related chapter from textbook and literature |
recitation by the student and class discussion |
|
12 |
Deterministic effects of radiation |
student previously reads the related chapter |
Lecture by teacher, class discussion, exercise |
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13 |
assignment 3 |
student reads the related chapter from textbook and literature |
recitation by the student and class discussion |
|
14 |
Stochastic effects of radiation |
student previously reads the related chapter |
Lecture by teacher, class discussion, exercise |
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15 |
assignment 4 |
student reads the related chapter from textbook and literature |
recitation by the student and class discussion |
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16/17 |
final exam |
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oral and written exams |
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Required Course Resources |
| Resource Type | Resource Name |
| Recommended Course Material(s) |
 Radiobiology for the radiologist, Eric J Hall, Amato J Giaccia, Wolters Kluwer, Lippincott Williams & Wilkins, Philadelphia, 2012
Radiologic science for technologists
Essentials of radiation biology and protection, Steve Forsier, Delmar, Cengage Learning, USA 2002
Nuclear Medicine and PET/CT, Paul E Christian, Kristen M Waterstram-Rich, MOSBY, 2007
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| |
| Required Course Material(s) |
Lecture notes
Problem and practice book
internet databases
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Assessment Methods and Assessment Criteria |
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Semester/Year Assessments |
Number |
Contribution Percentage |
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Mid-term Exams (Written, Oral, etc.) |
1 |
50 |
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Homeworks/Projects/Others |
4 |
50 |
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Total |
100 |
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Rate of Semester/Year Assessments to Success |
40 |
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Final Assessments
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100 |
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Rate of Final Assessments to Success
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60 |
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Total |
100 |
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| Contribution of the Course to Key Learning Outcomes |
| # | Key Learning Outcome | Contribution* |
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1 |
Lists and describes the functions of health organizations, explains how national and international health organizations are organized, and explains how to manage clinics. |
1 |
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2 |
owns some of the features of the human biological sciences (anatomy, physiology, pathology, cellular and biomolecular structure, radiologic anatomy, and so on.) related to Medical Physics applications |
3 |
|
3 |
explains and discusses the ethical and legal issues in the field of health care profession (eg, research ethics, data protection, privacy, reputation, ethics management). |
3 |
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4 |
explains the neccessary technical substructure for the qualified service in the future of Medical Physics. |
3 |
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5 |
explains the national legislative frameworks, regulations, guidelines and codes of practice of the European Community on the subject of medical Phyics |
3 |
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6 |
In order to explain the structure, function, the characteristics and the limitations, he/she uses the physical concepts, principles and theories in a detailed and quantitative way by covering the areas of medical physics. Also explains the use of medical devices in the field of medical physics. |
5 |
|
7 |
describes the properties of ionizing radiation (electromagnetic, electrons, ions, neutrons), and other physical agents (electrical energy, static electricity / magnetic fields, non-ionizing electromagnetic radiation, vibration, sound and ultrasound, laser) in a detailed and quantitive way. |
5 |
|
8 |
describes the useful and reverse effects of onizing radiation and different physical agents that have a link with medical devices by means of biological models in a numerical way and explains the factors affecting the magnitude of the biological effect. Explains the ways of manipulation to improve clinical outcomes. |
5 |
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9 |
explains deterministic / stochastic, early / late, teratogenic / genetic effects related to each physical agent |
5 |
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10 |
In order to review something in a systematic manner in the field of Medical Physics, he/she makes up a list of related literature in the fields of the General Physics, Medical Physics and Health physics. |
3 |
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11 |
uses the general concepts, principles and theories of physics to sort out clinical problems of safety / risk management related to the clinical use of medical devices, and on ionization radiation. |
2 |
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12 |
uses the general concepts,principles and theories of physics to transfer new devices and related techniques to the clinical environment. |
3 |
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13 |
designs digital clinical and biomedical studies based on meticulous and rigorous statistical base. |
2 |
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14 |
Uses statistical packages for the analysis of clinical and biomedical data. |
2 |
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15 |
tells the use of dosimetries used in medical physics based on physical concepts, principles and theories. |
1 |
|
16 |
identifies the dosimetric quantities of patients in each clinical process, and describes the methods for the measurement of these features. |
0 |
|
17 |
describes and explains different dosimetric quantities that are used and explains the relationship between dosimetric quantities (energy flux, kerma, absorbed dose). |
0 |
|
18 |
explains the principles of biological monitoring and dosimetry. |
0 |
|
19 |
Understands the nature of the anatomical medical images. |
0 |
|
20 |
During the administration of ionizing radiation to the patient, he/she determines the method and designs different applications to improve this method. |
0 |
| * Contribution levels are between 0 (not) and 5 (maximum). |
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| Student Workload - ECTS |
| Works | Number | Time (Hour) | Total Workload (Hour) |
| Course Related Works |
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Class Time (Exam weeks are excluded) |
14 |
3 |
42 |
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Out of Class Study (Preliminary Work, Practice) |
14 |
3 |
42 |
| Assesment Related Works |
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Homeworks, Projects, Others |
4 |
4 |
16 |
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Mid-term Exams (Written, Oral, etc.) |
1 |
2 |
2 |
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Final Exam |
1 |
2 |
2 |
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Total Workload: | 104 |
| Total Workload / 25 (h): | 4.16 |
| ECTS Credit: | 4 |
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