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Course Description Course Name : Phase III-Systems / Pathophysiology and Diseases Course Code : MED300 Course Type : Compulsory Level of Course : First Cycle Year of Study : 3 Course Semester : Fall and Spring (52 Weeks) ECTS : 60 Name of Lecturer(s) : Assoc.Prof.Dr. MEHMET ATA SEÇİLMİŞ Prof.Dr. ERGİN ŞİNGİRİK Prof.Dr. SERPİL ÖNDER Prof.Dr. FAZİLET AKSU Prof.Dr. NURAN ÖĞÜLENER Prof.Dr. CEMİL GÖÇMEN Prof.Dr. YUSUF KARATAŞ Prof.Dr. NACİYE YAKTUBAY DÖNDAŞ Assoc.Prof.Dr. EDA KUMCU KARABAL Prof.Dr. GÜLFİLİZ GÖNLÜŞEN Prof.Dr. SUZAN ZORLUDEMİR Prof.Dr. FİGEN DORAN Prof.Dr. MELEK ERGİN Prof.Dr. DERYA GÜMÜRDÜLÜ Prof.Dr. AYSUN HATİCEUĞUZ Asst.Prof.Dr. EMİNEKILIÇ BAĞIR Asst.Prof.Dr. ARBİL AÇIKALIN AVCI Prof.Dr. FATİH KÖKSAL Prof.Dr. FÜGEN YARKIN Prof.Dr. AKGÜN YAMAN Prof.Dr. MEHMET MACİT İLKİT Prof.Dr. İSMAİL SONER KOLTAŞ Prof.Dr. KIYMET AKSOY Prof.Dr. NURTEN DİKMEN Prof.Dr. ABDULLAH TULİ Prof.Dr. HALİL KASAP Prof.Dr. OSMAN DEMİRHAN Prof.Dr. DAVUT ALPTEKİN Prof.Dr. HÜSNÜ ÜMİT LÜLEYAP Prof.Dr. AYŞE DOĞAN Prof.Dr. ŞEREF ERDOĞAN Prof.Dr. AYŞE FİLİZ KOÇ Assoc.Prof.Dr. NURİ SELİM KADIOĞLU Prof.Dr. HÜSEYİN REFİK BURGUT Assoc.Prof.Dr. GÜLŞAH SEYDAOĞLU Prof.Dr. SAİME PAYDAŞ Prof.Dr. YAHYA SAĞLIKER Prof.Dr. NESLİHAN ARCA SEYREK Prof.Dr. İBRAHİM KARAYAYLALI Prof.Dr. MUSTAFA BALAL Prof.Dr. HİKMET AKKIZ Prof.Dr. MACİT ÜMRAN SANDIKÇI Assoc.Prof.Dr. YÜKSEL GÜMÜRDÜLÜ Assoc.Prof.Dr. SEDEFKURAN Assoc.Prof.Dr. OĞUZÜSKÜDAR Prof.Dr. İSMAİL FİKRİ BAŞLAMIŞLI Prof.Dr. BİROL GÜVENÇ Prof.Dr. EMEL GÜRKAN Prof.Dr. BEKİR TAMER TETİKER Prof.Dr. MURAT SERT Prof.Dr. EREN ERKEN Prof.Dr. SÜLEYMAN ÖZBEK Assoc.Prof.Dr. H.TURGUT ELBEK ÖZER Prof.Dr. MELEK KÖKSAL ERKİŞİ Prof.Dr. SEMRA PAYDAŞ Prof.Dr. BERKSOY ŞAHİN Assoc.Prof.Dr. İ. OĞUZKARA Prof.Dr. MUSTAFA DEMİRTAŞ Prof.Dr. AYHAN USAL Prof.Dr. MEHMET KANADAŞI Prof.Dr. MESUT DEMİR Prof.Dr. ABDİ BOZKURT Asst.Prof.Dr. ALİDENİZ Prof.Dr. ALİ KOCABAŞ Asst.Prof.Dr. SEDAT KULECİ Assoc.Prof.Dr. İSMAİL HANTA Prof.Dr. H.SALİH ZEKİ AKSU Assoc.Prof.Dr. BEHİCE KURTARAN Prof.Dr. YEŞİM TAŞOVA Asst.Prof.Dr. AYŞE SEZA İNAL Asst.Prof.Dr. ASLIHAN CANDEVİR Prof.Dr. SADIK EMRE ALHAN Prof.Dr. NECMİ AKSARAY Prof.Dr. EMİNE KOCABAŞ Assoc.Prof.Dr. DERYA ALABAZ Prof.Dr. ŞAKİR ALTUNBAŞAK Prof.Dr. M.ÖZLEM HERGÜNER Prof.Dr. MUSTAFA YILMAZ Prof.Dr. DERYA ALTINTAŞ Prof.Dr. BİLGİN YÜKSEL Prof.Dr. H.NESLİHAN ÖNENLİ MUNGAN Prof.Dr. ALİ KEMAL TOPALOĞLU Prof.Dr. YURDANUR KILINÇ Prof.Dr. ATİLA TANYELİ Assoc.Prof.Dr. SERHANKÜPELİ Prof.Dr. HATİCE İLGEN ŞAŞMAZ Prof.Dr. NEJAT NARLI Prof.Dr. ALİ ANARAT Prof.Dr. AYSUN KARABAY BAYAZIT Prof.Dr. NAZAN ÖZBARLAS Asst.Prof.Dr. SEVCAN ALINÇ ERDEM Prof.Dr. NURDAN EVLİYAOĞLU Prof.Dr. RIZA DİNÇER YILDIZDAŞ Assoc.Prof.Dr. GÖKHANTÜMGÖR Prof.Dr. AYŞE AVCI Assoc.Prof.Dr. AYŞEGÜL YOLGA TAHİROĞLU Assoc.Prof.Dr. GONCA KARATAŞ KARAKUŞ Asst.Prof.Dr. GONCA GÜL ÇELİK Prof.Dr. YUNUS EMRE EVLİCE Prof.Dr. NURGÜL ÖZPOYRAZ Prof.Dr. LUT TAMAM Prof.Dr. NECDET AYTAÇ Prof.Dr. BANU ELÇİN YOLDAŞCAN AVŞAR Prof.Dr. FERDİ TANIR Assoc.Prof.Dr. HAKAN DEMİRHİNDİ Asst.Prof.Dr. ERTAN KARA Prof.Dr. NAFİZ BOZDEMİR Assoc.Prof.Dr. ESRA SAATÇI Assoc.Prof.Dr. ERSİN AKPINAR Assoc.Prof.Dr. SEVGİ ÖZCAN PAYCI Assoc.Prof.Dr. HATİCE KURDAK GÜRBÜZ Prof.Dr. YAKUP SARICA Prof.Dr. ŞABAN FATİN REEL Prof.Dr. HACER BOZDEMİR Prof.Dr. MELTEM DEMİRKIRAN Assoc.Prof.Dr. ŞEBNEM BIÇAKCI Assoc.Prof.Dr. KEZBAN ASLAN Prof.Dr. HAMZA HALUK DEMİRYÜREK Prof.Dr. YALÇIN KEKEÇ Prof.Dr. ALPER AKINOĞLU Prof.Dr. ALİ HAYDAR ALPARSLAN Prof.Dr. HÜSNÜ SÖNMEZ Prof.Dr. ÖMER ALABAZ Assoc.Prof.Dr. GÜRHAN SAKMAN Assoc.Prof.Dr. CEM KAAN PARSAK Prof.Dr. ERDAL ÇETİNALP Prof.Dr. BÜLENT BOYAR Assoc.Prof.Dr. TAHSİN ERMAN Prof.Dr. HÜSEYİN BAĞDATOĞLU Prof.Dr. ALP İSKENDER GÖÇER Prof.Dr. METİN TUNA Assoc.Prof.Dr. DERVİŞ MANSURİ YILMAZ Prof.Dr. FATİME TUNCAY ÖZGÜNEN Prof.Dr. İSMAİL CÜNEYT EVRÜKE Prof.Dr. M.TURAN ÇETİN Asst.Prof.Dr. İBRAHİM FERHAT ÜRÜNSAK Assoc.Prof.Dr. SELİM BÜYÜKKURT Assoc.Prof.Dr. AHMET BARIŞ GÜZEL Asst.Prof.Dr. ÜMRAN KÜÇÜKGÖZ GÜLEÇ Prof.Dr. MEHMET FİKRET ÇETİK Prof.Dr. MUSTAFA METE KIROĞLU Prof.Dr. YÜKSEL GÖKEL Prof.Dr. ÜLKÜ TUNCER Asst.Prof.Dr. ÖZGÜR TARKAN Prof.Dr. MELTEM YAĞMUR Prof.Dr. AYŞE NİHAL DEMİRCAN Prof.Dr. GÜLHANIM HACIYAKUPOĞLU Prof.Dr. ZÜHTÜ TANSUĞ Prof.Dr. İBRAHİM ATİLLA ARIDOĞAN Prof.Dr. UĞUR ERKEN Prof.Dr. NİHAT SATAR Prof.Dr. ŞABAN DORAN Prof.Dr. İSMET TAN Assoc.Prof.Dr. CENK ÖZKAN Asst.Prof.Dr. ÖMER SUNKAR BİÇER Asst.Prof.Dr. MEHMET ALİDEVECİ Prof.Dr. MAHMUT OĞUZ Prof.Dr. MEHMET EMİN İNAL Prof.Dr. YUNUS KENAN BIÇAKCI Prof.Dr. SÜREYYA SOYUPAK Asst.Prof.Dr. HÜSEYİNTUĞSAN BALLI Prof.Dr. EROL AKGÜL Asst.Prof.Dr. ERKUT ERKURT Assoc.Prof.Dr. FUNDAGÜL ANDİÇ Prof.Dr. ZEYNEP DOĞRUCA YAPAR Assoc.Prof.Dr. GÜLGÜN BÜYÜKDERELİ Prof.Dr. TUNAY SARPEL Assoc.Prof.Dr. SİBELBAŞARAN Prof.Dr. RENGİN GÜZEL Assoc.Prof.Dr. HAFİZE YALINIZ Prof.Dr. OSMAN METİN YAVUZ Assoc.Prof.Dr. EROL KESİKTAŞ Asst.Prof.Dr. EYÜPHANGENCEL Prof.Dr. BEHNAN ALPER Assoc.Prof.Dr. AHMET HİLAL Asst.Prof.Dr. SÜLEYMAN ÖZDEMİR Prof.Dr. GÜLBİN BİNGÖL KARAKOÇ Learning Outcomes of the Course : Able to desrcibe pathophysiology of Hematopoietic System Diseases, the symptoms of these diseases, the main clinical, laboratory and histopathological findings, information about the general principles of diagnosis and treatment. Able to describe pathophysiology of the Cardiovascular System and Respiratory System Diseases, the symptoms of these diseases, the main clinical, laboratory and histopathological findings, general principles of diagnosis and treatment. Able to describe the symptoms and presenting symptoms of Gastrointestinal System (GIS), explain the pathophysiological mechanisms of related diseases and debate the differential diagnosis in children and adults. Able to describe the symptoms and presenting symptoms of Endocrine and Reproduction System Diseases, explain the pathophysiological mechanisms of related diseases, clinical, laboratuary and histopathological findings, and and debate the differential diagnosis. Able to describe Urinary System Diseases pathophysiology, the symptoms of these diseases, the main clinical, laboratory and histopathological findings, diagnostic and treatment information on to win the general principles. Able to descrine pathophysiology of Nervous System and Psychiatric Diseases, the symptoms of these diseases, the main clinical features and laboratory findings, diagnostic methods and disclose information about medications used to treat these diseases. Able to describe pathopsysiology of Musculoskeletal Diseases , symptoms of these diseases, the main clinical, laboratory and histopathological findings, information on the general principles of diagnosis and treatment has to win. Knowledge about the discipline of family medicine, communicate with family members when they visit, takes history of the patient, gains ability of health education. On physician-patient conversation can communicate effectively, perform call initiation, continuation and completion appropriately. Provide basic basic life support, shows multidisciplinary approach to the elderly individual. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : MED100 Phase I- Normal Structure and Function/ Cell-Tissue, Human Sciences MED200 Phase II-Normal Structure and Function/Systems Recommended Optional Programme Components : None Aim(s) of Course : The aim of the course, is to tell the highlighted clinical relevance of pathological processes on the basis of systems, to develop knowledge and skills of priority health problems by describing abnormal structure and function of the pre-clinical period. Course Contents : Clinical connections of phatological processes on basis of systems are emphasized, basic life support, professional skills laboratories, family medicine applications and horizontal and vertical integration supported in eight board courses. These boards are infectious diseases, hematopoietic system diseases, circulatory-respiratory system diseases, digestive system diseases, endocrine diseases, reproductive system, urinary system diseases, neurology and psychiatry disorders, musculoskeletal diseases. Language of Instruction : Turkish Work Place : Lecture Hall Laboratuary   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Infection and the immune system, microorganisms of transmission and the mechanism of infection, bacterial infections, pathologies, acute phase Preparatory work for the course Lecture hall and laboratory 2 Meningitis, viral, bacterial, mycobacterial infections, pathology, neonatal infections, tuberculosis, brucellosis, leprosy, leptospirosis, typhoid fever, Preparatory work for the course Lecture hall and laboratory 3 Otitis media, terasiklinler and chloramphenicol, and the sensitivity of detection of antibiotic susceptibility testing, antimicrobial chemoprophylaxis, viral diseases Preparatory work for the course Lecture hall and laboratory 4 The epidemiology of HIV, childhood and adult HIV, parasitic diseases, pathology, transmission and diagnosis, transmission routes of ectoparasites Preparatory work for the course Lecture hall and laboratory 5 Infectious diseases theoretical and practical course board exams The origin and development of blood cells, bone marrow hemopoiesis and control, and clinical significance of stem cells, hematopoietic growth factors, and pathology of the basic functions of the RES, spleen pathology, general description and classification of anemia, abnormal hemoglobins, blood biochemistry porphyries, porphyries, normocytic anemia, hemoglobinopathies, methehoglobinemiler, vitamin K, normal blood values ??in the newborn hmatolojik problems, thalassemia, hematologic problems, approaches and diagnostic methods. Family Medicine Practices Preparatory work for the course Lecture hall and laboratory 6 Eritrositozlar, hemolytic status, chronic diseases, anemia, paraproteinemias, iron metabolism disorders, iron deficiency anamisi, hemochromatosis, RES pathology, iron metebolizma disorder, medications, blood biochemistry, erythrocyte metabolism disorders, hereditary and acquired hemolytic anemia, macrocytic anemia, anemia drugs used megalobastik, thrombophilia, thrombocytopenia, hemostasis, pathophysiology, and antitrombolitik antiplatelet therapy, anticoagulants, ability to perform lumbar puncture, family medicine practices Preparatory work for the course Lecture hall and laboratory 7 Eritrositozlar, hemolytic status, chronic diseases, anemia, paraproteinemias, iron metabolism disorders, iron deficiency anamisi, hemochromatosis, RES pathology, iron metebolizma disorder, medications, blood biochemistry, erythrocyte metabolism disorders, hereditary and acquired hemolytic anemia, macrocytic anemia, anemia drugs used megalobastik, thrombophilia, thrombocytopenia, hemostasis, pathophysiology, and antitrombolitik antiplatelet therapy, anticoagulants, ability to perform lumbar puncture, family medicine practices Preparatory work for the course Lecture hall and laboratory 8 Holiday 9 Transfusion principles, indications, complications, blood banking and transfusion medicine, current practices, Hodgkin´s and non-Hodgkin´s lymphoma and radiotherapy, nuclear medicine hemoatolojide other lymphoproliferative diseases, antineoplastic drugs. Case discussion Artificial Lumbar Puncture skill, Practical Examination of Committee Preparatory work for the course Lecture hall and laboratory 10 Theoretical Examination Committee Introduction to the cardiovascular system, lipoprotein metabolism, biochemical mekanzimalar the pathogenesis of atherosclerosis, endocarditis, sympathomimetics, atherosclerosis, coronary heart disease, the development of risk factors and epidemiology, and the circulation of body fluids, the effects of each other by the coronary circulation, coronary artery disease, stable angina pectoris, atherosclerosis pathology, hypolipidemic drugs. Family Medicine Practice. Preparatory work for the course Lecture hall and laboratory 11 NO donors and inhibitors, antianginal drugs, ECG, ECG characteristics of children, valvular heart disease, coronary artery disease, acute coronary syndromes, myocardial infarction pathology, beta-receptor blockers darenerjik, arrhythmias, antiarrhythmic drugs, pericarditis, pericardial disease pathology, regulation of blood pressure and hypertension, etiology of heart failure in children, antihypertensive drugs, and miypkardit cardiomyopathies, myocardial infarction pathology. Atherosclerosis and myocardial infarction. Family Medicine Practice. Preparatory work for the course Lecture hall and laboratory 12 Acute rheumatic fever, diseases of endocardium and valve group, pathology, pathology of congenital heart disease, cyanotic and acyanotic congenital heart disease in the neonate and adult congenital heart disease, congenital heart disease, pathology, heart failure, pregnancy and heart disease, sympatolytics venous system diseases, cardiac diagnosis methods of drugs used in heart failure, peripheral artery disease, biochemical parameters in the diagnosis of cardiovascular diseases, respiratory pathophysiology, respiratory defense mechanisms of the upper respiratory tumors, hoarseness, and diagnostic agents of bacterial diseases transmitted through the respiratory tract, the respiratory tract factors and viral diseases transmitted by diagnosis, pathology of diseases of the upper respiratory tract. Physical examination (heart and respiratory examination) skills. Pharmacology lab. Life support course Preparatory work for the course Lecture hall and laboratory 13 Pneumonia, pneumonia pathology, childhood pneumonia, pulmonary vascular disease, pleural diseases, respiratory pharmacology, pulmonary hypertension and chronic cor pulmonale, pulmonary tuberculosis, pneumonia, emphysema, bronchiectasis, sleep-related breathing disorder, childhood tuberculosis, bacteriological diagnosis of pulmonary tuberculosis, adult asthma, pulmonary tuberculosis, pathology, nuclear medicine applications, circulatory and respiratory diseases, allergic respiratory diseases, chronic obstructive pulmonary disease, lung cancer, cystic fibrosis, bronchodilators, Basic Life Support Course. Family Medicine Practice. Preparatory work for the course Lecture hall and laboratory 14 Lung pathology of tumors of the pleura, the role of radiotherapy in lung cancer. respiratory failure, respiratory failure in children, obstructive pulmonary disease pathology, occupational diseases, meslekçevresel lung disease, pneumoconiosis, pneumonia, emphysema-bronchiectasis, lung tumors, interstitial lung diseases, smoking cessation methods, circulatory-respiratory system, radiology-1, 2,3. Basic Life Support Course. Family Medicine Practice. Practical Examination Committee Preparatory work for the course Lecture hall and laboratory 15 Theoretical Examination Committee. Functions of the digestive system. functions in the newborn gastrointestinal tract, and general concepts of pharmacology of the autonomic nervous system, motor abnormalities of the esophagus, esophagitis, and corrosive burns to the esophagus, mouth, and face approach, the principles of congenital anomalies, pathology of the mouth and esophagus, salivary glands pathology, and diaphragmatic hernia hiatus, bening and malignant diseases of the esophagus , gastritis and gastropathy, peptic ulcer disease, ulcerous lesions of the stomach, and digestive system, drugs that affect the medications used in the treatment of peptic ulcer disease, gastric tumors, pathology of tumors of the stomach. Breast Examination Skills. Pharmacology LAB Preparatory work for the course Lecture hall and laboratory 16 Prostaglandins, Parasympatholytics, abdominal pain, upper gastrointestinal bleeding, small bowel pathology absorption and circulatory disorders, inflammatory diseases and tumors of the small intestine. mouth, salivary glands, and esophageal pathology, pathology of gastric ulcers and tumors, primary malabsorption diseases, and the sprue, malabsorption secondary to the disease and protein-losing enteropathy, histamine and serotonin antagonists, which malabsorption of childhood diseases, emetic and anti-emetics, the digestive system transmitted infectious agents and the diagnosis of acute abdominal pain, ileus, ulcerative colitis, Crohn´s disease, inflammatory diseases of the colon, hernia, acute appendicitis, poisoning approach. Basic Life Support Course. Family Medicine Practice. Preparatory work for the course Lecture hall and laboratory 17 Gastrointestinal allergies, biochemical changes in amino acid metabolism, gastrointestinal diverticular disease, gastrointestinal polyps, colitis, irritable bowel disease, spastic colon and rectal tumors, colon tumors, antidiarrheal drugs, lower gastrointestinal bleeding, parasympathomimetics, anoraktal diseases, the basic principles of nutrition in childhood, childhood the age of eating disorders, viral factors and diagnosis of neonatal congenital and metabolic liver diseases, metabolic disorders in newborns, epidemiology and prevention of gastrointestinal diseases, jaundice, pathophysiology, medications, and liver diseases, neonatal metabolic disorders, gastrointestinal diseases, epidemiology and prevention, drugs, and liver and NASH alcoholic liver disease, liver function tests in childhood and familial congenital jaundice, acute - toxic hepatitis, laxative and purgative drugs. Breast examination skills. Pharmacology Laboratory. Small and large intestine pathology (PAT) LAB3-4. Family Medicine Practice. Preparatory work for the course Lecture hall and laboratory 18 Chronic hepatitis, cirrhosis, kraciğer disorders of mineral metabolism. LAB5 (PAT) - Hepatitis and cirrhosis of the liver pathology LaB6 (PAT) - Liver and gallbladder pathology of tumors LAB (PAT) - Pathology freelance work. Cystic diseases of the liver, and abscesses. Intoxication organisms, ascites, hepatic encephalopathy, hepatorenal syndrome, cirrhosis of the liver pathology, portal hypertension, cholestasis and primary biliary cirrhosis, liver tumors, anthelmintic drugs, crowns, hepatitis, liver tumors, pathology, acute pancreatitis, gallstones and cholecystitis, gall bladder and biliary tract tumors . Case discussion. Preparatory work for the course Lecture hall and laboratory 19 Familial Mediterranean Fever and porphyria, gallbladder pathology, pathology of the pancreas, pancreatic tumors, digestive system, radiology panel. Practical Examination Committee. Theoretical Examination Committee. Introduction to the endocrine system, endocrine pancreas and diabetes pathology, diseases of the pituitary gland, pituitary gland, hypothalamus, disease pathology, thyroid disease, diabetes mellitus. Family Medicine Practice. Preparatory work for the course Lecture hall and laboratory 20 Childhood diabetes, childhood hypoglycemia, diabetic retinopathy, hypertensive retinopathy and other retinal vascular diseases. Independent Study. Gynecological examination and skill Gbe. Pharmacology Laboratory. The parathyroid disease, adrenal gland disease, biochemical measurement of thyroid function, thyroid disease pathology. LAB1 (PAT) - Pathology of the endocrine system LAB2 (PAT) - Pathology of the endocrine system LAB3 (PAT) - cervix, corpus uteri pathology Adrenal disease pathology, childhood diseases, adrenal gland, adrenal biochemical measurement functions, the endocrine system farmokolojisine entrance, pituitary dwarfism, and other causes of short stature, growth, evaluation, development, evaluation, corticosteroids, and antagonists, adolescent-pubertal, pubertal disorders in childhood hypothyroidism, calcium drugs that affect the balance of insulin and oral antidiabetics, nuclear endocrinology (NCT). Preparatory work for the course Lecture hall and laboratory 21 Developmental genetics, gender, genetic control, Pathology of the vulva and vagina, cervix uteri pathology of disease, breast disease, breast disease pathology, pathology of the cervix and corpus uteri, ovarian pathology, mem pathology, drugs that affect the uterine smooth muscle, endometrium, endometrial disease pathophysiology and functional, ovarian pathophysiology, biochemical measurement of gonadal functions, menstrual cycle disorders, estrogen and progestins, and genito-urinary system changes that occur with aging, sexual dysfunction, placental development and function, fetal development, birth NORML. Gynecological examination and skill to conceive. Pharmacology Laboratory. Family Medicine Practice. Preparatory work for the course Lecture hall and laboratory 22 Holiday 23 Holiday 24 Monitoring of pregnancy (antenatal examination) and frequent complaints, abortion, ectopic pregnancy, pregnancy and infection. Basic Life Support Course. Radiotherapy in breast and gynecologic cancers, hypertensive diseases of pregnancy, Rh immunization, anabolic steroids and antiadrojenik drugs. Basic Life Support Course. Thyroid dysfunction drugs, placental pathology and gestational trophoblastic disease, post-partum hemorrhage, and puerperal infection puerperium. LAB8 (PAT) - Breast Pathology LAB9 (PAT) - Placental pathology Free operation pathology laboratory. Monitoring the biochemical changes of pregnancy, sexually transmitted diseases, the clinical approach, factors and diagnosis of sexually transmitted bacterial infection, a sexually transmitted virus infection factors and diagnosis, and the diagnosis of congenital infectious viruses, the epidemiology of sexually transmitted disease. Case Discussion Preparatory work for the course Lecture hall and laboratory 25 Venereal diseases, pathology, gynecologic cancer diagnosis yöntemlri, contraception, oral contraceptives, tetsis physiology, diseases of the testis. Practice Exam Theoretical Examination. Fonkisyonel kidney anatomy and function, acid-base balance and disorders, and disorders of sodium and water metabolism in children, fluid and electrolyte balance, acid-base balance, and fluid and electrolyte disorders, drugs, congenital anomalies of the urinary tract, potassium metabolism disorders, glomerulonephritis causes and clinical features, renal tubular acidosis in children, nephrotic syndrome pathogenesis, and clinical reasons. Preparatory work for the course Lecture hall and laboratory 26 The pathogenesis of glomerulonephritis, kidney, endocrine functions and disorders, edema, pathogenesis and causes, pathogenesis, and causes of proteinuria, glomerulonephritis, pathology, and clinical causes of acute and chronic nephritis tubulointertisyel. Basic Life Support Course. LAB1 (PAT) - Glomerulonephritis LAB2 (PAT) - Glomerulonephritis Tubulointertisyel pathogenesis of the disease, nephrotoxicity and dose adjustment of drugs in adults, acute renal failure in childhood acute renal failure, nephrotic syndrome in childhood. Pharmacology Laboratory. Kidney function tests and urine analysis, diuretics. Family Medicine Practice. Preparatory work for the course Lecture hall and laboratory 27 Chronic renal failure pathophysiology and clinical features, pathogenesis, and causes of hematuria, uremic bone disease, nephropathy diyabeteik pathophysiology, urinary obstruction, urinary tract stone disease, urinary tract infection, and diagnostic agents, genito-urinary bacteria and diagnosis of infectious agents, urinary tract infections, tuberculosis üriener system, children with urinary tract infections, kidney, ureter, bladder pathologies, pathologies of the prostate. Pathology freelance work. Reflux nephropathy, pathophysiology, and clinical pathophysiology of hypertension, hypertension in childhood hypertension, renal vascular disease, pathology, urinary antiseptics, urinary bladder, urethra, ureter disease, prostatic hyperplasia and cancer, bladder, urethra, ureter, pathology, testicular and prostate disease pathology. Pharmacology Laboratory. Case Discussion. Family Medicine Practices (Make-up) Preparatory work for the course Lecture hall and laboratory 28 Chronic renal failure pathophysiology and clinical features, pathogenesis, and causes of hematuria, uremic bone disease, nephropathy diyabeteik pathophysiology, urinary obstruction, urinary tract stone disease, urinary tract infection, and diagnostic agents, genito-urinary bacteria and diagnosis of infectious agents, urinary tract infections, tuberculosis üriener system, children with urinary tract infections, kidney, ureter, bladder pathologies, pathologies of the prostate. Pathology freelance work. Reflux nephropathy, pathophysiology, and clinical pathophysiology of hypertension, hypertension in childhood hypertension, renal vascular disease, pathology, urinary antiseptics, urinary bladder, urethra, ureter disease, prostatic hyperplasia and cancer, bladder, urethra, ureter, pathology, testicular and prostate disease pathology. Pharmacology Laboratory. Case Discussion. Family Medicine Practices (Make-up) Preparatory work for the course Lecture hall and laboratory 29 The basic concepts of neurological diseases (pyramidal, cerebellar, sensory systems) approach to the patient with neurologic symptoms, optical and oculomotor disorders saistem. Basic Life Support Course. Cranial nerve diseases, and disorders of consciousness, diagnosis and classification of mental disorders and Epidemiology, the patient-physician relationship, strabismus in children ryhsal development, higher cerebral functions of the central nervous system, congenital malformations, congenital spinal and cranial abnormalities, intracranial hypertension, psychiatric symptoms, and the basic concepts, head trauma, dementia, the cerebrospinal fluid biochemistry. Family Medicine Practices (Make-up) Preparatory work for the course Lecture hall and laboratory 30 Molecular genetics of neurodegenerative diseases, degenerative diseases of the nervous system santarla, ischemic cerebrovascular disease, mental retardation, CNS drugs, login, cerebrovascular pathology, SAK and vascular pathologies, psychosis, nevrozkavramı and separations, cerebellar system disorders, childhood and adolescent psychopathology input "children´s rights" 0-4 years preschool psychopathology "child abuse", aphasia, general anesthetics, mood disorders, antidepressant drugs, epilepsy, childhood convulsions, antiepileptic drugs, organic mental disorders. Family Medicine Practices (Make-up) Preparatory work for the course Lecture hall and laboratory 31 Demyelinating diseases, demyelinating diseases of SSS, somatoform and dissociative disorders, sexual dysfunction, extrapyramidal disorders, medications used to treat Parkinson´s, pervasive developmental disorders. LAB1 (PAT) FAQ disease pathology. Sleep disorders, personality disorders, anxiety disorders, hypnosedatives drugs, aging, genetics, pain, peripheral fascial paralysis, headaches. Preparatory work for the course Lecture hall and laboratory 32 CNS, metabolic disorders, substance abuse, narcotic analgesics and antagonists. Fundus examination and skill Otoscope. Pharmacology Laboratory. Komjenital muscle diseases, muscle diseases, pathology, schizophrenia and other psychotic disorders, motor neuron disease, intracranial tumors, tumor pathology of the nervous system santaral, psychosomatic TIP-KLP, knockout attention hyperactivity disorder, myasthenia and myasthenic syndromes, hearing loss, vertigo, neuroleptics, peripheral diseases of the nervous system. Preparatory work for the course Lecture hall and laboratory 33 Independent Study. Central nervous system imaging techniques, posture and gait disorders. Fundus examination and skill Otoscope. Pharmacology Laboratory. Spinal trauma, disc herniation, spinal stenosis, central nervous system stimuli, ganglion blockers, spinal and peripheral nerve tumors, peripheral nerve tumors. LAB3-4-5 (PAT), CNS tumors. LAB (PAT Pathology freelance work Practical Examination Committee Theoretical Examination Committee. Preparatory work for the course Lecture hall and laboratory 34 Orthopedic semptomşlar-I and II, musculoskeletal diseases, symptoms, clinical evaluation of plasma enzymes, hand injuries, fractures and dislocations, general knowledge about developmental dislocation of the hip, criminal cases, assessment, reporting, and the responsibility of the physician in medical applications, spine diseases, login, tumor markers, burns, fracture healing, fracture complications, vertebral deformity, Basic Principles of Medical Ethics 1: respect for life, providing the benefit, do no harm. Preparatory work for the course Lecture hall and laboratory 35 Extremity soft tissue injuries, illness, suffering and healing, the patient education., Connective tissue diseases, pathophysiology, pathology, diseases of connective tissue. Determination of Elastic Bandage Making Skills Practice Skills-fracture dislocation. Classification and diagnostic methods of arthritis, back pain, neck pain, osteoarthritis, rheumatic diseases Nonarticular, crystal arthropathies, reactive arthritis. Preparatory work for the course Lecture hall and laboratory 36 LAB1 (PAT) pathology of the skeletal system, skeletal system, nuclear medicine, aseptic necrosis, spondyloarthropathies, rheumatoid arthritis, congenital deformities, primary health care, diagnostic methods used in the first application. Panel: Bone and joint infections. Family medicine, risk management, evidence-based medicine (EBM) Introduction and general concepts, philosophy, medicine, research, research, research the types and values ??of types of evidence, oncologic approach to bone and soft tissue tumors, congenital deformities, ikimleler ethics, the principles of family medicine, topical anesthetics. Independent Study. Neuromuscular block, the drugs, osteoporosis, biochemical examples and sources of error. Preparatory work for the course Lecture hall and laboratory 37 LAB2 (PAT), bone and joint infections. LAB3 (PAT) of bone tumors. LAB4 (PAT) of bone tumors. LAB5 (PAT) of soft tissue tumors. Independent Study. Experimental Research: Clinical trials, why needed? Duration of ethical decision making in clinical practice, the use of clinical laboratory tests, clinical trials, randomized and non-randomized, single-blind and double-blind studies, sources of error v ethical issues in clinical research, and health care legislation, codes of medical ethics, medical acts and judge-patient relations, accidents and first aid, clinical trials to determine katılımcısayısının life data analysis, recording and evaluation of health care institutions, the basic principles of medical ethics, 2 Autonomy and respect for autonomy, lighting and consent. Panel: Soft tissue tumors. Determination of Elastic Bandage Making Skills Practice Skills-fracture dislocation. Preparatory work for the course Lecture hall and laboratory 38 Elderly patients, the pharmacokinetics of drugs and drug interactions. Panel: metabolic bone disease. Health profesyonle relations, medical research and research ethics, practices family medicine in Turkey and in the world, home care policies, periodic examinations. Free trial. Terminal phase approach to the individual and the family, to meet the stages of death, family medicine records, the individual family-based case-presentation, method-1, -2 family medicine clinic. Panel: Bone Tumors. The basic principles of medical ethics, 3: fair use of limited resources, the family approach to sexual problems, and protective services for the elderly socio-demographic characteristics. Life Support Course. Preparatory work for the course Lecture hall and laboratory 39 Advanced Module A Multidisciplinary Approach to the patient age. Workplace health and protection of home accidents, unusual cases, health care, non-narcotic analgesics, I. Basmakata patient records, centrally acting muscle relaxants, EBM steps: forming questions, search for evidence, evidence of critical appraisal, and monitoring of the patient is shared with the decision-making process. Preparatory work for the course Lecture hall and laboratory 40 Practical Examination Committee Theoretical Examination Committee Skills Laboratory Final Examination 41 Examination   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Braunwald H., Fauci A.S., Kasper D.L., Hauser S.L., Longo D.L., Jameson J.L., “Harrisons’ Principles of Internal Medicine”, 15th edition, McGraw-Hill Professional, (2001) Anafarta K, Göğüş Y., Bedük N., Arıkan N., “Temel Üroloji”, 1. baskı, Güneş Kitabevi, Ankara, (1998) Katzung, B. G., “Basic & Clinical Pharmacology”, 9. baskı, McGraw-Hill, International Edition, (2004) Kumar V., Cotran R.S., Robbins S.L., (Çeviri Ed. Çevikbaş U.), “Robbins Basic Pathology (Temel Patoloji)”, Nobel Tıp Kitapevleri, (2003) Anderson S.C., Cockayne S., “Clinical Chemistry: Concepts and Applications”, Mc Graw Hill, (2003) Evre 4 Blok 1 Ders notları, (2007-2008).  Braunwald H., Fauci A.S., Kasper D.L., Hauser S.L., Longo D.L., Jameson J.L., “Harrisons’ Principles of Internal Medicine”, 15th edition, McGraw-Hill Professional, (2001) Anafarta K, Göğüş Y., Bedük N., Arıkan N., “Temel Üroloji”, 1. baskı, Güneş Kitabevi, Ankara, (1998) Katzung, B. G., “Basic & Clinical Pharmacology”, 9. baskı, McGraw-Hill, International Edition, (2004) Kumar V., Cotran R.S., Robbins S.L., (Çeviri Ed. Çevikbaş U.), “Robbins Basic Pathology (Temel Patoloji)”, Nobel Tıp Kitapevleri, (2003) Anderson S.C., Cockayne S., “Clinical Chemistry: Concepts and Applications”, Mc Graw Hill, (2003) Evre 4 Blok 1 Ders notları, (2007-2008). Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 8 100     Homeworks/Projects/Others 0 0 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Describes the normal human body and mental structure, function and interaction in all stages of life. 5 2 Explains and sequences common physical and mental disorders-diseases’ epidemiology, pathology, symptoms, signs, prognosis, and treatments. 0 3 Has the knowledge of ethical principles and preventive medicine methods about creating conditions for healthy living and disease prevention. 3 4 Defines common diseases in our country by selecting current, reliable diagnostic methods and appropriate pharmacological, physical, nutritional, psychosocial treatment methods. 5 5 Understands, analyzes and evaluates health and illness components, process and result, uses the evidence-based methods and updated information in the treatment of patients. Adopts the principle of making a decision by evaluating prevailing evidence of the patient’s choice, and self-experiences. 4 6 Takes accurate, comprehensive and problem focused anamnesis, with a systematic approach to the individual makes physical examination and mental evaluation, decides by paying respect to patient privacy, secrets, honor, faith, cultural differences, sexual orientation. 4 7 In cases that requires emergency response such as significant function and loss of an organ; offers first aid and basic life support and plans the next process. 4 8 Makes differential diagnosis by approaching holistically to the patient, has the skills and competence of rational diagnosis and treatment planning, information about patient and disease management, as an individual and team member takes responsibility for unexpected circumstances, monitors and embraces the patient. 4 9 Makes Individual, family and community oriented health education, executes the field of work as an individual or as a team member, makes counseling, supervision, expertise, leadership. 5 10 Within the framework of the project which will be conducted, plans, manages the staff development of the team and their education, monitors the process and evaluates, works in partnership with other disciplines. 5 11 Develops a positive attitude towards lifelong learning and behavior, adopts the universal conditions required by the profession of medicine. 5 12 Improves self in cultural, artistic and social fields constantly as well as professional development, plays a part in social responsibility projects with other professional groups. 2 13 Has the ability to communicate intercultural, effectively communicates with patients, coworkers and other parts of the community, and supports ideas and suggestions for solutions with qualitative and quantitative data, transfers verbally and in writing by using Turkish correctly. 5 14 Have the philosophy of science, the limits and the accuracy of the knowledge, validity and reliability of the information, knows how to access information and evaluates information by using critical thinking skills, determines the learning needs and resources related to medicine, directs the learning by using the resources effectively. 5 15 Uses medical informatics and communication technologies along with computer software in required level in the field. 1 16 Understands socio-economic effects of health along with the social and behavioral aspects, by using at least one foreign language European Language Portfolio B1 level monitors information and progress in the field and communicates with colleagues. 3 17 Keeps accurate and reliable records, collects data, analyzes, deciphers epidemic, clinical and laboratory data and acts in accordance with ethical principles in the sharing of the results. 5 18 Bears susceptibility and responsibility in the subject of self-mental and physical health, workers´ health, labor and environment safety, individual and public health, becomes role model to society by developing professional attitude. 2 19 Knows the basic health care legislation, as an individual acts in accordance with regulations, laws, legislations and ethical rules about rights and responsibilities. 2 20 Uses professional autonomy, has sufficient experience to carry out preventive medicine service and capable of doing clinical applications in national and international standards. 4 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 35 30 1050     Out of Class Study (Preliminary Work, Practice) 35 6 210 Assesment Related Works     Homeworks, Projects, Others 0 0 0     Mid-term Exams (Written, Oral, etc.) 8 25 200     Final Exam 1 30 30 Total Workload: 1490 Total Workload / 25 (h): 59.6 ECTS Credit: 60