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  Course Description
Course Name : Protein Metabolism

Course Code : BY-732

Course Type : Optional

Level of Course : Second Cycle

Year of Study : 1

Course Semester : Spring (16 Weeks)

ECTS : 6

Name of Lecturer(s) : Prof.Dr. ELİF ORUÇ

Learning Outcomes of the Course : Describes the different types of amino acids, covalent backbone of proteins and the biological functions of proteins.
Discusses the oxidative degradation of amino acids and metabolism of one -carbon units.
Describes the urea cycle. Explains the pathways leading to ketogenicity and glucogenicity
Describes the pathways for protein catabolism.
Discusses the pathways of creatine and creatinine metabolism.

Mode of Delivery : Face-to-Face

Prerequisites and Co-Prerequisites : None

Recommended Optional Programme Components : None

Aim(s) of Course : This is the study of the pathways of amino acid and protein metabolism; emphasis on degradation and biosynthesis of amino acids and their derivatives; and inborn errors of amino acid metabolism. It also describes the urea cycle, ketogenicity, glucogenicity, creatine and creatinine metabolism and protein catabolism.

Course Contents : Describe the different types of amino acids, covalent backbone of proteins and the biological functions of proteins. Discuss the oxidative degradation of amino acids and metabolism of one -carbon units. the inborn errors of amino acid metabolism. Describe the urea cycle. Explain the pathways leading to ketogenicity and glucogenicity. Describe the pathways for protein catabolism. Discuss the pathways of creatine and creatinine metabolism.

Language of Instruction : Turkish

Work Place : Class


  Course Outline /Schedule (Weekly) Planned Learning Activities
Week Subject Student's Preliminary Work Learning Activities and Teaching Methods
1 Classes of amino acids Study the relevant chapter in the book lecture,discussion, presentation
2 Covalent backbone, tertiary and quaternary structure of proteins. Study the relevant chapter in the book lecture,discussion, presentation
3 Biological functions of proteins. Study the relevant chapter in the book lecture,discussion, presentation
4 Oxidative degradation of amino acids. Study the relevant chapter in the book lecture,discussion, presentation
5 Metabolism of one-carbon units. Study the relevant chapter in the book lecture,discussion, presentation
6 Biosynthesis of amino acids and their derivatives. Study the relevant chapter in the book lecture,discussion, presentation
7 Inborn error of amino acid metabolism. Study the relevant chapter in the book lecture,discussion, presentation
8 Mid-term exam Mid-term exam mid-term exam
9 The carbon skeleton of amino acids. Study the relevant chapter in the book lecture,discussion, presentation
10 Ketogenicity Study the relevant chapter in the book lecture,discussion, presentation
11 glucogenicity. Study the relevant chapter in the book lecture,discussion, presentation
12 Urea cycle and excretion of amino nitrogen. Study the relevant chapter in the book lecture,discussion, presentation
13 Protein catabolism. Study the relevant chapter in the book lecture,discussion, presentation
14 Creatine metabolism. Study the relevant chapter in the book lecture,discussion, presentation
15 Revision and evaluation. Study the relevant chapter in the book lecture,discussion, presentation
16/17 Final exam Final exam Final exam


  Required Course Resources
Resource Type Resource Name
Recommended Course Material(s)  Nelson DL. and Cox M., Lehninger Principles of Biochemistry, 5th edition, New York, 2008
Required Course Material(s)


  Assessment Methods and Assessment Criteria
Semester/Year Assessments Number Contribution Percentage
    Mid-term Exams (Written, Oral, etc.) 1 50
    Homeworks/Projects/Others 6 50
Total 100
Rate of Semester/Year Assessments to Success 40
 
Final Assessments 100
Rate of Final Assessments to Success 60
Total 100

  Contribution of the Course to Key Learning Outcomes
# Key Learning Outcome Contribution*
1 Has the advanced hypothetical and applied knowledges in biology field 4
2 Based on the bachelor´s level of qualification, develops and deepens the knowledge as a specialist in the biology 5
3 Uses the theoretical and practical knowledge he expertises in biology 5
4 Integrates and interprets the knowledge from different disciplines by his expertise in biology and generates new information. 5
5 Solves the problems of biology by using research methods. 5
6 Carries out an independent study requires expertise on biology 4
7 Develops and produces new strategic approaches and solves the unexpected problems in biology area by taking responsibilty 4
8 Assesses the knowledge he expertises through critical approach and makes leadership solving problems related to biological environments. 4
9 Systematically transfers the current developments in the field of biology and his/her studies to the person in biology field or other related fields by supporting qualitative and quantitative data 5
10 Uses at least one foreign language to keep up to date with the field to take part in scientific and social interaction groups to share information at international levels 5
11 Uses information and communication technologies as required in the biology field 3
12 In biology, uses statistical software programme to carry out scientific research and also uses information and communication technology in proficiency level of knowledge and skills to critically evaluate 1
13 Develops the strategy, policy and implementation plans in the issues related to the field of biology and treats the results obtained within standart of quality 3
14 Uses the knowledge, problem solving, and / or practical skills obtained in the Biology Field in interdisciplinary studies. 4
15 Oversees social, scientific, cultural and ethical values in order to collect, implement, interpret data in the Biology area 5
* Contribution levels are between 0 (not) and 5 (maximum).

  Student Workload - ECTS
Works Number Time (Hour) Total Workload (Hour)
Course Related Works
    Class Time (Exam weeks are excluded) 14 2 28
    Out of Class Study (Preliminary Work, Practice) 14 2 28
Assesment Related Works
    Homeworks, Projects, Others 6 12 72
    Mid-term Exams (Written, Oral, etc.) 1 10 10
    Final Exam 1 20 20
Total Workload: 158
Total Workload / 25 (h): 6.32
ECTS Credit: 6