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Course Description Course Name : Basic Immunology Course Code : TİM-501 Course Type : Optional Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall and Spring (16 Weeks) ECTS : 4 Name of Lecturer(s) : Prof.Dr. AKGÜN YAMAN Learning Outcomes of the Course : Defines the terms of natural and acquired immunity, cells and tissues in the immune system. Describes types of cellular immunity and effector mechanisms of CD4+ T lymphocytes,CD8+ cytolytic T lymphocytes . Specifies types and stages of humoral immune system. Describes effector functions of antibodies and complement system . Identifies the principles of autoimmunity and the location of infection in autoimmunity. Explains immune responses to tumors and transplants . Defines the types of hypersensitivity, rapid hipersensitivity and diseases caused by antibodies,antibody-antigen complexes and T lymphocytes . Explains the terms of primer and seconder immune deficiency and acquired immune deficiency . Describes the terms of passive acquired immunty, inactive vaccine, live vaccine and adjuvant. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : The aims of this lesson are to learn basic terms and mechanisms about immunology and get information about the structure and functions of the immune system. Course Contents : Natural and acquired immune response mechanisms are analyzed comparatively. Antigen recognition, capture and presentation phases, immune deficiencies, hypersensitivity reactions, vaccines and immunological methods used in laboratory are taught. Language of Instruction : Turkish Work Place : C.U Faculty of Medicine Department of Medical Microbiology meeting room   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Introduction to the Immune System Reading resources and lecture notes on the subject Verbal lecture, discussion 2 Natural immunity Reading resources and lecture notes on the subject Verbal lecture 3 Antigen capture and T lymphocyte presentation Reading resources and lecture notes on the subject Verbal lecture, presentation 4 Antigen recognition in acquired immune system Reading resources and lecture notes on the subject Verbal lecture, presentation 5 Cell dependent immune responses Reading resources and lecture notes on the subject Verbal lecture, presentation 6 Effector mechanisms of cellular immunity Reading resources and lecture notes on the subject Verbal lecture, presentation 7 Humoral immune response Reading resources and lecture notes on the subject Verbal lecture, presentation 8 Midterm exam Exam preperation Written exam 9 Effector mechanisms of humoral immunity Reading resources and lecture notes on the subject Verbal lecture, presentation 10 Immunological tolerance and autoimmunity Reading resources and lecture notes on the subject Verbal lecture, presentation 11 Immune responses to tumors and transplants Reading resources and lecture notes on the subject,article research Verbal lecture, presentation 12 Hypersensitivity diseases Reading resources and lecture notes on the subject Verbal lecture, presentation 13 Natural and acquired immune deficiencies Reading resources and lecture notes on the subject Verbal lecture 14 Immunological methods and their applications Reading resources and lecture notes on the subject,article research Verbal lecture, presentation 15 Vaccines Reading resources and lecture notes on the subject,article research Verbal lecture 16/17 Final exam Exam preperation Written exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Abbas AK, Lichtman AH. Translation: Camcıoğlu Y. Deniz G., Temel İmmünoloji; Immün sistem işlev ve bozuklukları. Istanbul Medical publishing. Istanbul Medical booktrade. 2007  Delves PJ, Martin SJ, Burton DR, Roitt IM, Translation editor: Ilıman MN, Assistant editor: Yıldız M, Basic Immunolgy. Atlas booktrade. 2008   Male D, Brostoff J, Roth DB, Roitt I, Immunology. seventh edition Required Course Material(s)  Bristol Sorensen, Joanne E. Streib, Matthew Strand, Barry Make, Patricia C. Giclas, Monika Fleshner, and James F. Jones, Denver and Boulder, Colo. Complement activation in a model of chronic fatigue syndrome. J allergy Clın Immunol August 2003   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 60     Homeworks/Projects/Others 2 40 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Identifies morphological and physiological characteristics of microorganisms 2 2 Identificates genomic structures of microorganisms 2 3 Explains microorganisms virulance factors and infection mechanisms. 4 4 Defines the mechanisms of immune response and defense against microorganisms 5 5 Lists the antimicrobial agents. 2 6 Defines the mechanisms of resistance development against antimicrobial agents. 2 7 Lists the microscopy, culture, serological and molecular diagnostic principles used in the laboratory diagnosis of infectious microorganisms. 1 8 Lists microbiological tests for identification of microorganisms 2 9 Implements and applies the methods used in the period from receipt of the clinical specimens up to identification of the causative agent . 4 10 Prepares a suitable media, applicates the staining methods, biochemical tests and molecular diagnostic methods to identify microorganisms from clinical samples. 2 11 Applies the biochemical tests and basic microbiological staining methods which are necessary for microbiological identification . 2 12 Determines the microorganisms by using basic molecular diagnostic techniques. 1 13 Works individually or as a team member related to the field. 4 14 Carries out the missions given within the scope of research projects. 4 15 Develops a positive attitude and behaviour towards lifelong learning. 5 16 Evaluates own knowledge and new-learned knowledge in a critical view after graduating. 5 17 Communicates effectively. 5 18 Transfers their own ideas and developments in the field, and offers solutions visually and verbally supporting with qualitative and quantitative data. 3 19 Applies ethical principles during study, evaluation and result sharing. 5 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 3 42     Out of Class Study (Preliminary Work, Practice) 14 2 28 Assesment Related Works     Homeworks, Projects, Others 2 3 6     Mid-term Exams (Written, Oral, etc.) 1 5 5     Final Exam 1 10 10 Total Workload: 91 Total Workload / 25 (h): 3.64 ECTS Credit: 4