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Course Description Course Name : Evaluation of pain and analgesia using experimental animals Course Code : FAR529 Course Type : Optional Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall and Spring (16 Weeks) ECTS : 4 Name of Lecturer(s) : Prof.Dr. FAZİLET AKSU Learning Outcomes of the Course : Learns the definition of pain and terms related to pain. Learns about the transmission of pain Knows the chemical mediators of pain Knows the drugs used for pain treatment and analgesic action mechanisms Learns the experimental pain models and their accordance with clinical pain . Knows the statistical methods used in pain and analgesia experiments. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : To inform about the experimental pain and analgesia methods developed to investigate the action mechanism of drugs used for pain treatment and the effect of new analgesics. Course Contents : Definition of pain and general information, pain related terms, pain mechanisms, drugs used for pain treatment, methods assessing pain and analgesia in experimental animals, evaluation of results. Language of Instruction : Turkish Work Place : Classroom and laboratory.   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Pain and analgesia: Definition and history, pain hypothesis and terms Suggested reading Power Point presentation 2 Transmission of pain Suggested reading Power Point presentation 3 Pain mediators Suggested reading Power Point presentation 4 Pain pathways Suggested reading Power Point presentation 5 Pain pharmacology,the priciples of pain treatment and drugs used Suggested reading Power Point presentation 6 Scientific and ethical rules of experimental pain Suggested reading Power Point presentation 7 Experimental methods used for pain and analgesia: General evaluation Suggested reading Power Point presentation 8 Mid-term exam Exam study Oral examination 9 Thermal stimulus tests Reviewing the suggested article PP presentation,article analysis, practice 10 Mechanical stimulus tests Reviewing the suggested article PP presentation,article analysis, practice 11 Chemical stimulus tests Reviewing the suggested article PP presentation,article analysis, practice 12 Electrical stimulus tests Reviewing the suggested article PP presentation,article analysis, practice 13 Observation of behaviours and scoring Reviewing the suggested article PP presentation,article analysis, practice 14 Calculation of % analgesic effect , drawing dose-response curve graph Reviewing the suggested article Studies on the results of sample experiments 15 Statistics in pain experiments Reviewing the suggested article Studies on the results of sample experiments 16/17 Final exam Exam study Oral exam, participation in lessons and discussions, homework   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Goodman and Gilman´s The Pharmacologic Basis of Therapeutics  Wall & Melzack´s Textbook of Pain  Pain Research: Methods and Protocols (Z. David Luo) Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 60     Homeworks/Projects/Others 3 40 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Students gain the ability to research on the areas like preventing irrational drug use detecting the problems due to drug use 5 2 Students gain basic pharmacological information 4 3 Students have the ability to take on the responsibilities of pharmacology 5 4 Students know the experimental research techniques in pharmacology 5 5 Students gain the ability to present their knowledge in an academic environment 5 6 Students have an ability to access scientific information 5 7 Students are informed about pharmacovigilance 3 8 Students have the ability to apply the basic principles of rational drug use on daily practice 4 9 Students gain the ability to take place in the in vitro/ in vivo animal experiments 5 10 Students gain the ability to plan and conduct experimental pharmacological projects and analyze the experimental results. 5 11 Students gain the ability to follow present literature in the field of pharmacology 5 12 Students guide the assistant health personnel to receive pharmacology education 3 13 Students are informed about rational drug use 4 14 Students know the pharmacological research areas 4 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 2 28     Out of Class Study (Preliminary Work, Practice) 14 2 28 Assesment Related Works     Homeworks, Projects, Others 3 10 30     Mid-term Exams (Written, Oral, etc.) 1 10 10     Final Exam 1 10 10 Total Workload: 106 Total Workload / 25 (h): 4.24 ECTS Credit: 4