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| Course Description |
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| Course Name |
: |
METABOLISM OF PLASMA LIPIDS |
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| Course Code |
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BİK-532 |
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| Course Type |
: |
Optional |
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| Level of Course |
: |
Second Cycle |
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| Year of Study |
: |
1 |
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| Course Semester |
: |
Fall and Spring (16 Weeks) |
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| ECTS |
: |
4 |
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| Name of Lecturer(s) |
: |
Prof.Dr. ABDULLAH TULİ
Prof.Dr. KIYMET AKSOY
Prof.Dr. LEVENT KAYRIN
Prof.Dr. NURTEN DİKMEN
Prof.Dr. MEHMET AKİF ÇÜRÜK
Assoc.Prof.Dr. TAMER C. İNAL
Asst.Prof.Dr. ÖZLEM GÖRÜROĞLU ÖZTÜRK
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| Learning Outcomes of the Course |
: |
classifies lipids.
describes the physiologic importance of lipids.
defines the digestion and absorbtion of lipids.
comprehends lipoprotein metabolism.
explains lipid metabolism in different tissues.
tells regulatory mechanisms for lipoprotein metabolism.
knows laboratory techniques defining disorders of lipoprotein metabolism.
describes the mechanism of atherosclerosis.
explains dyslipidemias.
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| Mode of Delivery |
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Face-to-Face |
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| Prerequisites and Co-Prerequisites |
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None |
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| Recommended Optional Programme Components |
: |
None |
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| Aim(s) of Course |
: |
The aim of this course is to enable students learn the structure, functions and metabolism of lipids. |
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| Course Contents |
: |
Classification of lipids, Physiologic importance of lipids, Digestion and absorbtion of lipids, Metabolism of lipoproteins, Lipid metabolism in different tissues, Mechanisn of atherosclerosis, Dyslipidemias, Laboratory techniques used in lipid metabolism. |
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| Language of Instruction |
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Turkish |
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| Work Place |
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Medical Faculty, Seminar Hall of Biochemistry Department |
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Course Outline /Schedule (Weekly) Planned Learning Activities |
| Week | Subject | Student's Preliminary Work | Learning Activities and Teaching Methods |
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1 |
Structure of lipids |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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2 |
Oxydation and biosynthesis of fatty acids |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
|
3 |
Biosynthesis and physiologic functions of triglicerides |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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4 |
Biosynthesis and physiologic functions of phospholipids |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
|
5 |
Biosynthesis and physiologic functions of sphingolipids |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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6 |
Biosynthesis and physiologic functions of cholesterol |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
|
7 |
Lipid metabolism in hepatic tissue |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
|
8 |
Lipid metabolism in cardiac and adipose tissue |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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9 |
Mid-term examination |
revision of previous lessons |
classic exam |
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10 |
Regulation of lipoprotein metabolism: Genetic regulation |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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11 |
Regulation of lipoprotein metabolism: Enzymes |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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12 |
Regulation of lipoprotein metabolism: Receptors |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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13 |
Laboratory techiques used in lipoprotein metabolism |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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14 |
Atherosclerosis |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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15 |
Dyslipidemias |
reading related pages, presentations, articles, assignment |
lecturing, illustration, group discussion, interactive study |
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16/17 |
Final examination |
revision of previous lessons |
classic exam |
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Required Course Resources |
| Resource Type | Resource Name |
| Recommended Course Material(s) |
 Betteridge DJ, Illingworth DR, Shepherd J. Lipoproteins in Health and Disease, Arnold, London, 1999.
Nelson DL, Cox MM. Lehninger Principles of Biochemistry, 6th Ed., W. H. Freeman and Company, 2013.
Devlin TM. Textbook of Biochemistry with Clinical Correlations, 5th Ed., Wiley-Liss, New York, 2002.
Burtis CA, Ashwood ER, Bruns DE. Tietz Clinical Chemistry and Molecular Diagnostics, 5th Ed., Elsevier, 2012.
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| Required Course Material(s) | |
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Assessment Methods and Assessment Criteria |
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Semester/Year Assessments |
Number |
Contribution Percentage |
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Mid-term Exams (Written, Oral, etc.) |
1 |
80 |
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Homeworks/Projects/Others |
3 |
20 |
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Total |
100 |
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Rate of Semester/Year Assessments to Success |
40 |
| |
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Final Assessments
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100 |
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Rate of Final Assessments to Success
|
60 |
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Total |
100 |
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| Contribution of the Course to Key Learning Outcomes |
| # | Key Learning Outcome | Contribution* |
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1 |
Applies innovations in laboratory processes by doing research. |
1 |
|
2 |
Comprehends the interaction of biochemistry with the other scientific fields. |
0 |
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3 |
Knows experimental methods in biochemistry. |
1 |
|
4 |
Takes part in in-vitro/in-vivo animal research studies. |
0 |
|
5 |
Carries out studies in the field of biochemistry as a member of a team. |
3 |
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6 |
Gains ongoing professional skills. |
5 |
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7 |
Comprehends basic information about the field of biochemistry. |
5 |
|
8 |
Interprets the factors and phases that effect the laboratory results. |
1 |
|
9 |
Uses laboratory tools. |
0 |
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10 |
Knows the ethical and legal characteristics of laboratory processes, and interpretes economical value of these processes for the country. |
0 |
|
11 |
Supports a scientific research. |
3 |
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12 |
Interpretes scientific research results which are carried out. |
3 |
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13 |
Generates a report from the conclusion of the scientific research. |
3 |
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14 |
Knows biochemical sampling rules. |
2 |
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15 |
Studies and makes research in laboratory settings. |
3 |
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16 |
Corporates with the other members of the team in an efficient, sensitive and respectfull way. |
3 |
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17 |
Interpretes and corrolates biochemical data and theoretical concept. |
1 |
| * Contribution levels are between 0 (not) and 5 (maximum). |
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| Student Workload - ECTS |
| Works | Number | Time (Hour) | Total Workload (Hour) |
| Course Related Works |
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Class Time (Exam weeks are excluded) |
14 |
2 |
28 |
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Out of Class Study (Preliminary Work, Practice) |
14 |
2 |
28 |
| Assesment Related Works |
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Homeworks, Projects, Others |
3 |
5 |
15 |
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Mid-term Exams (Written, Oral, etc.) |
1 |
10 |
10 |
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Final Exam |
1 |
10 |
10 |
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Total Workload: | 91 |
| Total Workload / 25 (h): | 3.64 |
| ECTS Credit: | 4 |
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