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| Course Description |
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| Course Name |
: |
BASIC BIOCHEMISTRY I |
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| Course Code |
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BİK-501 |
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| Course Type |
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Compulsory |
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| Level of Course |
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Second Cycle |
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| Year of Study |
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1 |
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| Course Semester |
: |
Fall (16 Weeks) |
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| ECTS |
: |
6 |
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| Name of Lecturer(s) |
: |
Prof.Dr. ABDULLAH TULİ
Prof.Dr. LEVENT KAYRIN
Prof.Dr. KIYMET AKSOY
Prof.Dr. NURTEN DİKMEN
Prof.Dr. MEHMET AKİF ÇÜRÜK
Assoc.Prof.Dr. TAMER C. İNAL
Asst.Prof.Dr. ÖZLEM GÖRÜROĞLU ÖZTÜRK
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| Learning Outcomes of the Course |
: |
students who complete this course succesfully could have knowledge about:
main structure of organic compounds in organism. gases. solutions, pH, buffer, acide-bases.
carbohydrates, lipids, aminoacids
proteins (special proteins, hemoglobine, myoglobine,collogen), nucleic acides, vitamins and co-enzymes
enzymes, enzyme kinetics, general survey of metabolism, energy metabolism
glycolysis, control of glycolysis, pentose phosphate patway, TCA circle, oxidation, reduction, electrone transportation, oxidative phosphorilation, ATP synthesis
catabolism of fatty acides, synthesis of fatty acides. synthesis of phospholipides and triglyserides, cholesterol and prosthoglandines.
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| Mode of Delivery |
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Face-to-Face |
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| Prerequisites and Co-Prerequisites |
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None |
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| Recommended Optional Programme Components |
: |
None |
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| Aim(s) of Course |
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The aim of this course is to enable students learn the sturucture and the functions of macromolecules which constitute the organisms |
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| Course Contents |
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The main structure of organic compounds in organisms. Gases. Solutions, pH, buffer, acid-bases. Carbohydrates, lipids, aminoacides. Proteins (special proteins; hemoglobine, myoglobine, collogen), Nucleic acids. vitamins and coenzymes. Enzymes, enzyme kinetics. General study of metabolisms. Energy metabolism. Glicolysis, control of glicolysis, pentose-phosphate pathway, TCA cycle. Oxidation-reduction, electron transportation, oxidative phosphorilation, ATP synthesis. Catabolism of fatty acids, synthesis of fatty acids. Synthesis of phospholipids and trigliserids, general information about cholesterol and prostoglandines |
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| Language of Instruction |
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Turkish |
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| Work Place |
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Medical Faculty, Seminar Hall of Biochemistry Department |
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Course Outline /Schedule (Weekly) Planned Learning Activities |
| Week | Subject | Student's Preliminary Work | Learning Activities and Teaching Methods |
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1 |
Chemical Compounds in Biochemistry, Solutions |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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2 |
Acide-bases, Buffers |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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3 |
Biochemistry of Carbohydrates |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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4 |
Biochemistry of Amino Acids |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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5 |
Biochemistry of Proteins
Hemoglobin and Myoglobin |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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6 |
Biochemistry of Lipids |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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7 |
Biochemistry of Nucleic Acids |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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8 |
Vitamins |
text to be read, web survey, presentations,assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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9 |
Mid-term examination |
revision of the courses |
classic question-answer exam |
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10 |
Enzymes and Enzyme kinetics |
text to be read, web survey, presentations, assignment, sample questions |
lecturing illustrations, grup discussions, brain storming, seminar |
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11 |
Introduction to Metabolism |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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12 |
Nutrition and Trace Elements |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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13 |
Glycolysis and The Oxidation of Pyruvate |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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14 |
Glyconeogenesis, Regulantion of Blood Glucose, Pentose Phosphate Pathway |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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15 |
Crebs cycle, Electrone Transport Chain, ATP Synthesis |
text to be read, web survey, presentations,assignment, sample questions |
lecturing, illustrations, grup discussions, brain storming, seminar |
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16/17 |
Final examination |
revision of the courses |
classic question-answer exam |
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Required Course Resources |
| Resource Type | Resource Name |
| Recommended Course Material(s) |
 Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil PA. Harper’s Illustrated Biochemistry, 29th Ed., Mc Graw Hill and Lange, 2012.
Boynes JW, Dominiczak MH. Medical Biochemistry, 3rd Ed., Mosby Elsevier, 2009.
Nelson DL, Cox MM. Lehninger Principles of Biochemistry, 6th Ed., W. H. Freeman and Company, 2013.
Mathews CK, van Holde KE. Biochemistry, The Benjamin/Cumming Pub, 1990.
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| Required Course Material(s) | |
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Assessment Methods and Assessment Criteria |
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Semester/Year Assessments |
Number |
Contribution Percentage |
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Mid-term Exams (Written, Oral, etc.) |
1 |
80 |
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Homeworks/Projects/Others |
3 |
20 |
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Total |
100 |
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Rate of Semester/Year Assessments to Success |
40 |
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Final Assessments
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100 |
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Rate of Final Assessments to Success
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60 |
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Total |
100 |
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| Contribution of the Course to Key Learning Outcomes |
| # | Key Learning Outcome | Contribution* |
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1 |
Applies innovations in laboratory processes by doing research. |
1 |
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2 |
Comprehends the interaction of biochemistry with the other scientific fields. |
4 |
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3 |
Knows experimental methods in biochemistry. |
2 |
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4 |
Takes part in in-vitro/in-vivo animal research studies. |
0 |
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5 |
Carries out studies in the field of biochemistry as a member of a team. |
0 |
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6 |
Gains ongoing professional skills. |
5 |
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7 |
Comprehends basic information about the field of biochemistry. |
5 |
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8 |
Interprets the factors and phases that effect the laboratory results. |
3 |
|
9 |
Uses laboratory tools. |
0 |
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10 |
Knows the ethical and legal characteristics of laboratory processes, and interpretes economical value of these processes for the country. |
0 |
|
11 |
Supports a scientific research. |
0 |
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12 |
Interpretes scientific research results which are carried out. |
4 |
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13 |
Generates a report from the conclusion of the scientific research. |
3 |
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14 |
Knows biochemical sampling rules. |
0 |
|
15 |
Studies and makes research in laboratory settings. |
0 |
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16 |
Corporates with the other members of the team in an efficient, sensitive and respectfull way. |
0 |
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17 |
Interpretes and corrolates biochemical data and theoretical concept. |
2 |
| * Contribution levels are between 0 (not) and 5 (maximum). |
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| Student Workload - ECTS |
| Works | Number | Time (Hour) | Total Workload (Hour) |
| Course Related Works |
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Class Time (Exam weeks are excluded) |
14 |
4 |
56 |
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Out of Class Study (Preliminary Work, Practice) |
14 |
3 |
42 |
| Assesment Related Works |
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Homeworks, Projects, Others |
3 |
7 |
21 |
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Mid-term Exams (Written, Oral, etc.) |
1 |
10 |
10 |
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Final Exam |
1 |
20 |
20 |
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Total Workload: | 149 |
| Total Workload / 25 (h): | 5.96 |
| ECTS Credit: | 6 |
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