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Course Description Course Name : General Microbiology Course Code : MİK-501 Course Type : Optional Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall and Spring (16 Weeks) ECTS : 6 Name of Lecturer(s) : Prof.Dr. FATİH KÖKSAL Learning Outcomes of the Course : Distinguishes the differences between prokaryotes and eukaryotes. Describes the general characteristics of bacteria, fungi and viruses. Defines the metabolism of microorganisms, enzymes, and the characteristics of reproduction. Defines the mechanisms of pathogenicity and infectivity of microorganisms Defines the genetic structure of microorganisms. Lists the main features of the immune defense against infections. Explains the antimicrobials, their effective mechanisms and mechanisms of antimicrobial resistance. Lists the working principles of microbiology laboratory. Lists the methods of production and identification of microorganisms. Explains the sterilization, disinfection and antisepsis methods. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : Providing information about the classification of microorganisms, structures, reproductive environments and production, genetic and metabolic characteristics, microbiology working principles and major basic methods. Course Contents : Providing basic information about application areas of microbiology, general characteristics, metabolism, enzymes, growth characteristics, pathogenicity, the mechanism of infection and genetic characteristicsof bacteria, fungi and viruses, immune defense, control of microbial growth, the principles of microbiology laboratory, security of laboratory, equipments and basic diagnostic methods. Language of Instruction : Turkish Work Place : C.U Faculty of Medicine Department of Medical Microbiology convention hall and laboratories.   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Introduction to microbiology and history Reading resources and lecture notes about the subject Verbal lecture, presentation 2 Application areas of microbiology Reading resources and lecture notes about the subject Verbal lecture, presentation 3 Classification of microorganisms Reading resources and lecture notes about the subject Verbal lecture, presentation 4 Metabolism of microorganisms, enzymes and growth characteristics Reading resources and lecture notes about the subject Verbal lecture, presentation 5 Symbiosis, pathogenicity of microorganisms, the mechanism of infection Reading resources and lecture notes about the subject Verbal lecture, presentation 6 Genetics of microorganisms Genetic material structure and transformation of bacteria Transformation, conjugation, transduction Reading resources and lecture notes about the subject Verbal lecture, presentation 7 Viral replication Genetic changes in viruses (mutations and recombination) Fungus Plasmid , Fungus Viruses and Parasitism Reading resources and lecture notes about the subject Verbal lecture, presentation 8 Midterm Exam Exam prepation Written exam 9 Main features of the immune defense against infections, Natural and acquired immunity Reading resources and lecture notes about the subject Verbal lecture, presentation 10 Control of microbial growth Antimicrobials and their effective mechanisms Emerging resistance to antimicrobials and methods for detecting resistance Reading resources and lecture notes about the subject Verbal lecture, presentation 11 Principles of microbiology laboratory practice Reading resources and lecture notes about the subject Verbal lecture, presentation 12 Providing laboratory security , maintenance and use of laboratory equipment Reading resources and lecture notes about the subject Verbal lecture, presentation 13 The production of microorganisms, media, bacteria cultivation methods Reading resources and lecture notes about the subject Verbal lecture, presentation 14 Staining methods, gram staining and identification methods Reading resources and lecture notes about the subject Verbal lecture, presentation 15 Sterilization, disinfection and antisepsis methods Reading resources and lecture notes about the subject Verbal lecture, presentation 16/17 Final Exam Exam Preparation Written Exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Basic Lab Clinical Bacteriology. 2. BASKI J.Vandepıtte WHO 2003  Lecture notes and slides  Human Microbiology (Lifelines).P.H.Simon Taylo& Francis 2002 Required Course Material(s)  Essential Microbiolgy S.Hogg J.Willey& Sons 2005.  Temel ve Klinik Mikrobiyoloji, Şemsettin Ustaçelebi. Güneş Kitabevi   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 60     Homeworks/Projects/Others 1 40 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Identifies morphological and physiological characteristics of microorganisms 5 2 Identificates genomic structures of microorganisms 3 3 Explains microorganisms virulance factors and infection mechanisms. 4 4 Defines the mechanisms of immune response and defense against microorganisms 3 5 Lists the antimicrobial agents. 4 6 Defines the mechanisms of resistance development against antimicrobial agents. 4 7 Lists the microscopy, culture, serological and molecular diagnostic principles used in the laboratory diagnosis of infectious microorganisms. 5 8 Lists microbiological tests for identification of microorganisms 5 9 Implements and applies the methods used in the period from receipt of the clinical specimens up to identification of the causative agent . 2 10 Prepares a suitable media, applicates the staining methods, biochemical tests and molecular diagnostic methods to identify microorganisms from clinical samples. 2 11 Applies the biochemical tests and basic microbiological staining methods which are necessary for microbiological identification . 5 12 Determines the microorganisms by using basic molecular diagnostic techniques. 1 13 Works individually or as a team member related to the field. 2 14 Carries out the missions given within the scope of research projects. 1 15 Develops a positive attitude and behaviour towards lifelong learning. 1 16 Evaluates own knowledge and new-learned knowledge in a critical view after graduating. 1 17 Communicates effectively. 1 18 Transfers their own ideas and developments in the field, and offers solutions visually and verbally supporting with qualitative and quantitative data. 1 19 Applies ethical principles during study, evaluation and result sharing. 1 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 4 56     Out of Class Study (Preliminary Work, Practice) 14 4 56 Assesment Related Works     Homeworks, Projects, Others 1 4 4     Mid-term Exams (Written, Oral, etc.) 1 10 10     Final Exam 1 20 20 Total Workload: 146 Total Workload / 25 (h): 5.84 ECTS Credit: 6