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Course Description Course Name : Ultrastructure and functions of the cell Course Code : HİS 501 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall (16 Weeks) ECTS : 6 Name of Lecturer(s) : Prof.Dr. SAİT POLAT Prof.Dr. UFUK ÖZGÜ METE Learning Outcomes of the Course : Identifies cell membrane at ultrastructure level Distinguishes cell nucleus and nuclear components at ultrastructure level Identifies cell organelles ultrastructurally. Identifies inclusions ultrastructurally Interrelates ultrastructure and function. Distinguishes ultrastructural deviations. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : HİS511 Techniques of Electron Microscopy I Recommended Optional Programme Components : None Aim(s) of Course : Aim of the course is to examine and evaluate cells and cellular components at ultrastructural level. Course Contents : Ultrastructures and functions of cell membrane, nucleus, nucleolus, mitochondria, ribosome, Golgi apparatus, lysosome, rough-surfaced endoplasmic reticulum, smooth-surfaced endoplasmic reticulum, peroxisome, Annulate lamella, cytoskeleton and inclusions Language of Instruction : Turkish Work Place : Lecture room, laboratory   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Ultrastructure of the cell membrane Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 2 Ultrastructure of the nucleus Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 3 Ultrastructure of the nucleolus Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 4 Ultrastructure of the mitochondria Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 5 Ultrastructure of the ribosome Self-study, reading recommended soruces Presentation, question-answer, discussion, micrograph evaluation 6 Ultrastructure of the Golgi Apparatus Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 7 Ultrastructure of the lysosomes Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 8 Midterm exam Self-study Oral exam 9 Ultrastructure of the rough endoplasmic reticulum Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 10 Ultrastructure of the smooth endoplasmic reticulum Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 11 Ultrastructure of the peroxisomes Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 12 Ultrastructure of the annulate lamellae Self-study, reading recommended soruces Presentation, question-answer, discussion, micrograph evaluation 13 Ultrastructure of the cytoskeleton Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 14 Ultrastructure of the inclusions Self-study, reading recommended sources Presentation, question-answer, discussion, micrograph evaluation 15 Seminar Self-study, literature search, article search Presentation, report preparation 16/17 Final Self-study Exam, micrograph evaluation   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Lecture powerpoint presentations  Bozzola JJ, Russell LD. Electron Microscopy, Second edition.1998.  Pavelka M, Roth J. Functional Ultrastructure: atlas of tissue biology and pathology. 2005. Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 50     Homeworks/Projects/Others 1 50 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Can identify the structures of the organ at microscope 0 2 Can recognize cells and tissues at light microscope 0 3 Tell the main histological features of cells and tissues. 5 4 Corelate the structure and function of cells. 5 5 Have knowledge of the histologic features of organ systems. 0 6 Have knowledge of embryo development, developmental disorders and the mechanisms. 0 7 Define the methods of light and electron microscopic examination and tissue preparation. 5 8 Have knowledge of general principles about cell culture, histochemistry and immunohistochemistry. 0 9 Prepare solutions and tissues for light and electron microscopic studies . 0 10 Apply the basic methods of staining. 0 11 Distinguish tissue and organ systems in light microscopic level. 0 12 Perform studies as a team member or indıvidual. 0 13 Perform tasks which is given in research projects. 0 14 Develop positive attitudes and behaviors towards lifelong learning. 0 15 Determine and direct needs and resources of learnings by using resources effectively. 0 16 Evaluate knowledges and skills of the master degree critically. 0 17 Communicate effectively. 0 18 Relay ideas and solution offers about current developments in studies by supporting them with quantitative and qualitative data visually and verbally. 0 19 Know the importance of the ethical principles in research studies, evaluations and results. 0 20 Can recognize different staining methods 0 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 5 70     Out of Class Study (Preliminary Work, Practice) 14 5 70 Assesment Related Works     Homeworks, Projects, Others 1 2 2     Mid-term Exams (Written, Oral, etc.) 1 2 2     Final Exam 1 2 2 Total Workload: 146 Total Workload / 25 (h): 5.84 ECTS Credit: 6