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  Course Description
Course Name : Histochemistry

Course Code : HİS510

Course Type : Optional

Level of Course : Second Cycle

Year of Study : 1

Course Semester : Fall and Spring (16 Weeks)

ECTS : 6

Name of Lecturer(s) : Asst.Prof.Dr. HÜLYAÖZGÜR
Prof.Dr. ÖZGÜL TAP

Learning Outcomes of the Course : Defines the histochemistry
Knows the chemical basis of the histochemical staining methods.
Knows the histochemical methods used for connective tissue staining.
Knows the histochemical methods used for staining the nuclear elements and the cytoplasmic granules.
Knows the histochemical methods used for staining the cytoplasmic lipids, carbohydrate and mucoproteins.
Knows the histochemical methods used for staining the enzymes.

Mode of Delivery : Face-to-Face

Prerequisites and Co-Prerequisites : HİS512 Techniques of Light Microscopy I

Recommended Optional Programme Components : None

Aim(s) of Course : Learning and performing special staining techniques which are used to observe chemical substances in the cell or tissue at microscopic level.

Course Contents : Defining histochemistry and chemical basics of histochemistry staining methods, Histochemical methods for connective tissues, Histochemical methods for nuclear elements and cytoplasmic granules, Histochemical methods for lipids, carbonhydrates and mucoproteins, Histochemical methods for enzymes.

Language of Instruction : Turkish

Work Place : Lecture room, laboratory


  Course Outline /Schedule (Weekly) Planned Learning Activities
Week Subject Student's Preliminary Work Learning Activities and Teaching Methods
1 Definition of Histochemistry and application fields. Self-study, reading recommended soruces Presentation
2 The chemical basis of staining of histological samples and staining Self-study, reading recommended soruces Presentation
3 Metachromasia and metachromatic dyes. Self-study, reading recommended soruces Presentation and laboratory practice
4 Histochemical techniques and its application which are used for the connective tissue Self-study, reading recommended soruces Presentation and laboratory practice
5 Homework Review of the literature, self-study Laboratory practice
6 Histochemical techniques and its application which are used to show cytoplasmic granules Self-study, reading recommended soruces Presentation and laboratory practice
7 Histochemical techniques and its application used for nuclear elements Self-study, reading recommended soruces Presentation and laboratory practice
8 Exam Self-study, reading recommended soruces Exam
9 Histochemical techniques and its application used for lipids Self-study, reading recommended soruces Presentation and laboratory practice
10 Histochemical techniques and its application used for carbonhydrates and mucoproteins Self-study, reading recommended soruces Presentation and laboratory practice
11 Homework Review of the literature, self-study Laboratory practice
12 Histochemical techniques and its application used to show pigments and minerales Self-study, reading recommended soruces Presentation and laboratory practice
13 Homework Review of the literature, self-study Laboratory practice
14 Histochemical techniques and its application used for enzymes Self-study, reading recommended soruces Presentation and laboratory practice
15 Homework Review of the literature, self-study Laboratory practice
16/17 Final Self-study, reading recommended soruces Exam


  Required Course Resources
Resource Type Resource Name
Recommended Course Material(s)  Kaya, M. Genel histoloji ders notları. Ç.Ü. Tıp Fakültesi yayınları. No:10, 2005
 Demir R. Histolojik boyama teknikleri. Palme yayıncılık. Ankara, 2001.
 Luna LG.: Manual of histologic staining methods of the armed forces institute of pathology. 3rd ed. Mc Graw Hill book co. 1968.
 Preece,A.:A manual for Histologic Technicians. Third Edition.Little Brown, 1972.
Required Course Material(s)  Drury,RAB, Walligton,EA, Cameron,R.: Carleton´s Histological Technique.Fourth


  Assessment Methods and Assessment Criteria
Semester/Year Assessments Number Contribution Percentage
    Mid-term Exams (Written, Oral, etc.) 1 60
    Homeworks/Projects/Others 4 40
Total 100
Rate of Semester/Year Assessments to Success 40
 
Final Assessments 100
Rate of Final Assessments to Success 60
Total 100

  Contribution of the Course to Key Learning Outcomes
# Key Learning Outcome Contribution*
1 Tell the main histological features of cells and tissues. 0
2 Corelate the structure and function of cells. 0
3 Have knowledge of the histologic features of organ systems. 0
4 Have knowledge of embryo development, developmental disorders and the mechanisms. 0
5 Define the methods of light and electron microscopic examination and tissue preparation. 5
6 Have knowledge of general principles about cell culture, histochemistry and immunohistochemistry. 5
7 Prepare solutions and tissues for light and electron microscopic studies . 5
8 Apply the basic methods of staining. 5
9 Distinguish tissue and organ systems in light microscopic level. 3
10 Perform studies as a team member or indıvidual. 2
11 Perform tasks which is given in research projects. 5
12 Develop positive attitudes and behaviors towards lifelong learning. 0
13 Determine and direct needs and resources of learnings by using resources effectively. 0
14 Evaluate knowledges and skills of the master degree critically. 3
15 Communicate effectively. 0
16 Relay ideas and solution offers about current developments in studies by supporting them with quantitative and qualitative data visually and verbally. 2
17 Know the importance of the ethical principles in research studies, evaluations and results. 0
* Contribution levels are between 0 (not) and 5 (maximum).

  Student Workload - ECTS
Works Number Time (Hour) Total Workload (Hour)
Course Related Works
    Class Time (Exam weeks are excluded) 14 5 70
    Out of Class Study (Preliminary Work, Practice) 14 3 42
Assesment Related Works
    Homeworks, Projects, Others 4 8 32
    Mid-term Exams (Written, Oral, etc.) 1 1 1
    Final Exam 1 1 1
Total Workload: 146
Total Workload / 25 (h): 5.84
ECTS Credit: 6