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  Course Description
Course Name : Bioreactors and Their use in Plant Tissue Cultures.

Course Code : BT-537

Course Type : Optional

Level of Course : Second Cycle

Year of Study : 1

Course Semester : Fall (16 Weeks)

ECTS : 6

Name of Lecturer(s) : Prof.Dr. SAADET BÜYÜKALACA

Learning Outcomes of the Course : Gains theoretical and conceptual information about bioreactors
Learns the working principle of bioreactors used in plant tissue culture and performs technical and cultural applications.
Gains information about the methods to follow user research theoretically and practically .
Practises how to put the research findings and theoretical information into practice.
Identifies the type of the bioreactor fit for purpose and develops methods to solve existing problems.

Mode of Delivery : Face-to-Face

Prerequisites and Co-Prerequisites : None

Recommended Optional Programme Components : None

Aim(s) of Course : To recognize different types of bioreactors and learn the objectives and methods of use in plant biotechnology.

Course Contents : Types of bioreactors used in the Plant tissue culture and control principles, meristem, callus, somatic embryogenesis and developments about secondary metabolite production in bioreactors.

Language of Instruction : Turkish

Work Place : Postgraduate classroom of the department


  Course Outline /Schedule (Weekly) Planned Learning Activities
Week Subject Student's Preliminary Work Learning Activities and Teaching Methods
1 Introduction to bioreactors Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
2 Bioreactor considerations Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
3 Culture conditions and requirements in bioreactors: cell morphology, aeration and mixing Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
4 Culture conditions and requirements in bioreactors: shear sensitivity, ph and temperature Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
5 Types and characteristics of bioreactors used in tissue culture Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
6 Type and characteristics of bioreactors used in tissue culture Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
7 Mid-term exam Preparation to exam Written exam
8 Design of a bioreactor Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
9 Control systems of a bioreactor Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
10 Callus culture Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
11 In vitro propagation in bioreactors Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
12 Somatic embryogenesis in bioreactors Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
13 Production of secondary metabolites by plant cell suspension cultures using bioreactors Straight narrative technique, powerpoint presentation and discussion
14 Production of secondary metabolites by organ culture in bioreactors Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
15 Production of shoots and hairy roots in bioreactors Reading recommended books and given lecture notes Straight narrative technique, powerpoint presentation and discussion
16/17 Final exam Preparation to final exam Written exam


  Required Course Resources
Resource Type Resource Name
Recommended Course Material(s)  Powerpoint presentation given by lecturer
 Maria Teresa Giardi 2010 Bio-farm for Nutraceuticals
 Özcan, S., Gürel, E. ve Babaoğlu, M. (Eds.) 2001. Bitki Biyoteknolojisi. Vol. II. Genetik Mühendisliği ve Uygulamaları. S.Ü. Basımevi, Konya.
 Payne, G. F.; Bringi, V.; Prince C. L.; Shuler, M. L. Plant cell and tissue culture in liquid systems.
Required Course Material(s)  Babaoğlu, M., Gürel, E. ve Özcan, S. (Eds.) 2002. Bitki Biyoteknolojisi. Vol. I. Doku kültürü ve Uygulamaları. S.Ü. Basımevi, Konya.


  Assessment Methods and Assessment Criteria
Semester/Year Assessments Number Contribution Percentage
    Mid-term Exams (Written, Oral, etc.) 1 60
    Homeworks/Projects/Others 2 40
Total 100
Rate of Semester/Year Assessments to Success 40
 
Final Assessments 100
Rate of Final Assessments to Success 60
Total 100

  Contribution of the Course to Key Learning Outcomes
# Key Learning Outcome Contribution*
1 Evaluates and directs his level of learning in the field of knowledge and skills with his expert level critically. 3
2 Transfers current developments in the field of his work, supporting them with quantitative and qualitative data, systematically to the area outside of the field, written, orally and visually. 3
3 Follows national and international publications and attends social interactions and scientific studies in international level, communicates in at least in one foreign language in order to share studies on international base. 3
4 Uses advanced information and communication technologies along with the required level of their computer software. 4
5 Uses the knowledge in his field for problem solving and / or practical skills in interdisciplinary studies. 4
6 Improves common knowledge accumulation concerning the Biotechnology in the frame of basic theory and practices. 3
7 Is aware of scientific, ethical and social values and handles research process with this frame. 5
8 Handles theories, hypothesis, opinions in the field of Biotechnology with an objective sceptic, logical, analytical manner and evaluates them in critical point of view. 3
9 Gains comprehensive information about natural and applied sciences and its limits with modern techniques and methods applied. 5
10 Improves and increases the knowledge to an expert level in the field of biotechnology 5
11 Understands the interdisciplinary interaction associated with biotechnology. 4
12 Integrates and interprets the knowledge from different disciplines by his expertrise in biology and generate new information 4
13 Analizes the problems encountered in the field of research methods. 3
14 Carries out a study requiring expertise in the field independently. 3
15 Developes new strategic approaches and takes resposibility for analitical solutions for unpredictable complicated problems encountered in applications related to biotechnology. 3
16 Demonstrates leadership in the required environment to solve problems associated with biotechnology. 2
* Contribution levels are between 0 (not) and 5 (maximum).

  Student Workload - ECTS
Works Number Time (Hour) Total Workload (Hour)
Course Related Works
    Class Time (Exam weeks are excluded) 14 4 56
    Out of Class Study (Preliminary Work, Practice) 28 2 56
Assesment Related Works
    Homeworks, Projects, Others 2 10 20
    Mid-term Exams (Written, Oral, etc.) 1 14 14
    Final Exam 1 14 14
Total Workload: 160
Total Workload / 25 (h): 6.4
ECTS Credit: 6