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  Course Description
Course Name : Introduction to Bioinformatics

Course Code : ZO-615

Course Type : Optional

Level of Course : Second Cycle

Year of Study : 1

Course Semester : Fall (16 Weeks)

ECTS : 6

Name of Lecturer(s) : Prof.Dr. ZEYNEL CEBECİ

Learning Outcomes of the Course : The students comprehend the basic issues in bioinformatics,
search for information on bioinformatics resources,
work with gene, genome and protein databases,
understand BLAST algorithms,
query for homologies in nucleotide and protein sequences,
produce phylogenetic charts and graphs,
search genomic, proteomic, taxonomic and bibilographical information for species, genes and/or proteins.

Mode of Delivery : Face-to-Face

Prerequisites and Co-Prerequisites : None

Recommended Optional Programme Components : None

Aim(s) of Course : This course aims to teach the bioinformatic information resources; protein and gene databases; and BLAS algorithms for similarity analysis of gene and protein sequences.

Course Contents : This course includes the bionformatics information resources; BLAST search and interperation for nulcleotide and protein sequences; searching and analysing data in gene, genome and protein databases; and homology search for a specific gene or protein.

Language of Instruction : Turkish

Work Place : Classroom


  Course Outline /Schedule (Weekly) Planned Learning Activities
Week Subject Student's Preliminary Work Learning Activities and Teaching Methods
1 Introduction to bioinformatics: Terms, concepts and definitions none none
2 Organization of bioinformatics data, Information systems none none
3 Nucleic acids, amino acids, and introduction to protein synthesis none none
4 Genomic and proteomic information resources and systems none none
5 Global, local and multiple aligment algorithms none none
6 BLAST algorithms and Genebank none none
7 Similarity search with BLAST for protein and nucleotid sequences none none
8 Midterm exam none none
9 Phylogenetic trees none none
10 Project works 1 none none
11 Project works 2 none none
12 Project works 3 none none
13 Project works 4 none none
14 Project works 5 none none
15 Preperation for the final exam none none
16/17 Final exam none none


  Required Course Resources
Resource Type Resource Name
Recommended Course Material(s)  Weissig, H. (2005). Computer Skills for Biotechnology. http://www.bioinformaticscourses.com/BIOL358/lectures.html
 David Mount. Bioinformatics: Sequence and Genome Analysis, Second Edition
 Richard Durbin, Sean R. Eddy, Anders Krogh, Graeme Mitchison. Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids.
 Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. Wiley-Interscience
 D. Lopresti (2010). Introduction to Bioinformatics. http://www.lehigh.edu/~inbios21/PDF/Fall2010/Lopresti_10082010.pdf
 M Gerstein. Bioinformatics Introduction . http://bioinfo.mbb.yale.edu/mbb452a/intro/
 SB Nagl. Introduction to Bioinformatics. http://www.imtech.res.in/raghava/slides/dbase.ppt
 N.C. Jones, P.l A. Pevzner (2004) An Introduction to Bioinformatics Algorithms.ISBN-10: 0262101068
 T Can (2009). Introduction to Bioinformatics. http://ocw.metu.edu.tr/course/view.php?id=37
Required Course Material(s)  S. Taylor. Introduction to Bioinformatics. http://www.compbio.ox.ac.uk/presentations/CBRGPostGrad2008_ptI.pdf
 NCBI - http://www.ncbi.nlm.nih.gov
 Weissig H. (2005). Bioinformatics Applications in Target Identification and Validation. http://www.bioinformaticscourses.com/targetid/lecture2005.html


  Assessment Methods and Assessment Criteria
Semester/Year Assessments Number Contribution Percentage
    Mid-term Exams (Written, Oral, etc.) 1 60
    Homeworks/Projects/Others 4 40
Total 100
Rate of Semester/Year Assessments to Success 40
 
Final Assessments 100
Rate of Final Assessments to Success 60
Total 100

  Contribution of the Course to Key Learning Outcomes
# Key Learning Outcome Contribution*
1 At the end of this programme, the students improve and deepen their knowledge in the field of Animal Science by building on the knowledge and competence acquired at the undergraduate level and can employ interdisciplinary interaction in their field of study. 5
2 The students interpret and generate new information and theories in specific fields related to Animal Science using the theoretical and practical knowledge at masters level. Also, they can reveal the cause-effect relationship regarding the problems in their field of study and employ scientific research methods to generate possible solutions. 5
3 The students independently identify potential problems and carry out research studies aiming at solutions in the field of Animal Science. Also, they investigate and develop strategic approaches for potential problems that may arise related to the particular studies. 4
4 The students access and compile information about the latest developments and fundamental sources in the particular field and reach a new synthesis by evaluating and interpreting the existing research. They can make use of this acquired knowledge to practice the profession effectively and follow the improving implementations in the field. 5
5 The students use information in the field of Animal Science, through compiling, interpreting and synthesising it, in order to make social contributions. They make evaluations by creating a plan and framework and taking specific total quality criteria into consideration. They use the skills and knowledge acquired in the field of Animal Science in joint projects with other disciplines. 5
6 The students discuss and pass on the acquired knowledge based on their work in the field by making written and oral presentations. They have speaking and writing competence in at least one foreign language at a level that enables them to keep up with the requirements of the age. They express their ideas clearly using the tools of information and communication technologies. 0
* Contribution levels are between 0 (not) and 5 (maximum).

  Student Workload - ECTS
Works Number Time (Hour) Total Workload (Hour)
Course Related Works
    Class Time (Exam weeks are excluded) 13 4 52
    Out of Class Study (Preliminary Work, Practice) 5 10 50
Assesment Related Works
    Homeworks, Projects, Others 4 10 40
    Mid-term Exams (Written, Oral, etc.) 1 3 3
    Final Exam 1 3 3
Total Workload: 148
Total Workload / 25 (h): 5.92
ECTS Credit: 6