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  Course Description
Course Name : Biochemistry I

Course Code : DEN181

Course Type : Compulsory

Level of Course : First Cycle

Year of Study : 1

Course Semester : Fall and Spring (32 Weeks)

ECTS : 2

Name of Lecturer(s) : Prof.Dr. ABDULLAH TULİ
Prof.Dr. MEHMET AKİF ÇÜRÜK
Prof.Dr. LEVENT KAYRIN
Asst.Prof.Dr. ÖZLEM GÖRÜROĞLU ÖZTÜRK
Assoc.Prof.Dr. TAMER C. İNAL

Learning Outcomes of the Course : Explain basic biochemical structures and mechanisms
Explain nutrition biochemistry mechanisms
Learn and explain the structure and methabolism of lipids, carbonhydrates, proteins and nucleic acids

Mode of Delivery : Face-to-Face

Prerequisites and Co-Prerequisites : DEN186 Medical Biology

Recommended Optional Programme Components : None

Aim(s) of Course : Evaluate and clarify the biochemical events within life at system, organ, cellular and molecular level

Course Contents : Lpids, proteins, carbonhdrates, enzymes, hormones and biochemical cycles.

Language of Instruction : Turkish

Work Place : Classroom assigned for 1st year dental students and Basic Medical Sciences Laboratory of Dental College


  Course Outline /Schedule (Weekly) Planned Learning Activities
Week Subject Student's Preliminary Work Learning Activities and Teaching Methods
1 Introduction to Biochemistry HANDOUTS Lecture and oral presentation
2 Amino acids and proteins HANDOUTS Discussion and oral presentation
3 Amino acids and proteins HANDOUTS Discussion and oral presentation
4 Carbohydrates HANDOUTS Discussion and oral presentation
5 Lipids HANDOUTS Discussion and oral presentation
6 Nucleic acids HANDOUTS Discussion and oral presentation
7 Enzymes HANDOUTS Discussion and oral presentation
8 Enzymes HANDOUTS Discussion and oral presentation
9 Vitamines HANDOUTS Discussion and oral presentation
10 Vitamines HANDOUTS Discussion and oral presentation
11 Minerals and nutrition biochemistry HANDOUTS Discussion and oral presentation
12 Minerals and nutrition biochemistry HANDOUTS Discussion and oral presentation
13 1st Midterm Exam HANDOUTS
14 Glycolysis, Gluconeogenesis HANDOUTS Discussion and oral presentation
15 Glycolysis, Gluconeogenesis HANDOUTS Discussion and oral presentation
16 Tricarboxylic acid cycle HANDOUTS Discussion and oral presentation
17 Tricarboxylic acid cycle HANDOUTS Discussion and oral presentation
18 Synthesis and storage of carbohydrates HANDOUTS Discussion and oral presentation
19 Synthesis and storage of carbohydrates HANDOUTS Lecture and oral presentation
20 Electron transport system HANDOUTS Discussion and oral presentation
21 Lipid metabolism: Fatty acid catabolism HANDOUTS Discussion and oral presentation
22 Lipid metabolism: Fatty acid catabolism HANDOUTS Discussion and oral presentation
23 2nd Midterm HANDOUTS
24 Lipid metabolism: Triglycerols and phospolipide metabolism HANDOUTS Discussion and oral presentation
25 Biosynthesis and storage of lipids. Synthesis of fatty acids HANDOUTS Discussion and oral presentation
26 Biosynthesis and storage of lipids. Synthesis of fatty acids HANDOUTS Discussion and oral presentation
27 Biosynthesis and storage of lipids. Structure and biosynthesis of cholesterol HANDOUTS Discussion and oral presentation
28 Biosynthesis and storage of lipids. Structure and biosynthesis of cholesterol HANDOUTS Discussion and oral presentation
29 Biosynthesis and storage of lipids. Structure and biosynthesis of cholesterol HANDOUTS Discussion and oral presentation
30 Water, electrolytes, acid-base equilibrium HANDOUTS Discussion and oral presentation
31 Water, electrolytes, acid-base equilibrium HANDOUTS Discussion and oral presentation
32/33/34 Final Exam HANDOUTS


  Required Course Resources
Resource Type Resource Name
Recommended Course Material(s)  Murray RK, Granner DK, Rodwell VW. Harper´s illustrated biochemistry, 29th Ed., McGraw-Hill Lange, 2012.
 Nelson LD, Cox MM. Lehninger Principles of Biochemistry, 6th Ed., W. H. Freeman and Company, 2013.
 Harvey RA, Champe PC. Lippincotts Illustrated Reviews Serisinden Biyokimya, 2nci Baskı, Nobel Tıp Kitabevleri, 1997.
 Onat T, Emerk K, Süzmen E. İnsan Biyokimyası, Palme Yayıncılık, Ankara, 2002.
 Baynes JW, Dominiczak MH. Medical Biochemistry, 3rd Ed., Mosby Elsevier, 2009.
 Levine M. Topics in dental biochemistry, Springer, Oklohama, 2011.
Required Course Material(s)


  Assessment Methods and Assessment Criteria
Semester/Year Assessments Number Contribution Percentage
    Mid-term Exams (Written, Oral, etc.) 2 50
    Homeworks/Projects/Others 0 50
Total 100
Rate of Semester/Year Assessments to Success 40
 
Final Assessments 100
Rate of Final Assessments to Success 60
Total 100

  Contribution of the Course to Key Learning Outcomes
# Key Learning Outcome Contribution*
1 Understand the concepts and relationships between concepts in the field of dentistry and have advanced contemporary theoretical and practical knowledge in the field of health care. 3
2 Have the ability to evaluate the nature, resource, limits, accuracy, reliability, and validity of knowledge. 3
3 Have the knowledge of discovering, evaluating and applying scientific information in dental field. 3
4 Be aware of the importance of ethical principles and ethical rules. 1
5 Be able to use advanced theoretical and practical knowledge regarding dentistry on advanced level 2
6 Be able to use the computer programs, related technology and educational tools in dentistry 1
7 Be able to take responsibility, either individually or as a team member, in solving complicated and unpredictable problems related to dental applications 1
8 Be able to critically assess acquired advanced knowledge and skills related to dentistry 4
9 Competent in specifying learning-needs and resources and guid the learning process by using resources effectively 2
10 Capable of developing and internalizing a positive attitude towards lifelong learning 1
11 Be qualified in instructing people or institutions on matters related to dentistry, transferring ideas and solving problems in a written or oral form, receiving thoughts, requirements and expectations of related people and institutions 2
12 Share professional information with both experts and people who are unfamiliar to this field 3
13 Capable of following professional information and interacting with international colleagues using at least one foreign language at European Language Portfolio B1 level 1
14 Be proficient in utilizing information and communication technologies on computer software at least at the level required by the European Computer Driving License in the field of dentistry. 1
15 Able to observe and evaluate contemporary developments in dentistry 2
16 Capable of using verbal and written Turkish language correctly and expressing herself/himself 3
17 Act according to the duties, the laws related to rights and responsibilities, regulations, legislation and professional ethical rules 1
18 Improve continuously in his/her own profession, as well as skills in accordance with scientific, social, cultural and artistic fields by identifying learning needs. 1
19 Have sound information about understanding the healthy and unhealthy invidual´s structure, the physiological functions and behaviors, and the interaction between health and physical and social environment 5
20 Have adequate experience on dental clinical applications 0
* Contribution levels are between 0 (not) and 5 (maximum).

  Student Workload - ECTS
Works Number Time (Hour) Total Workload (Hour)
Course Related Works
    Class Time (Exam weeks are excluded) 29 1 29
    Out of Class Study (Preliminary Work, Practice) 29 0 0
Assesment Related Works
    Homeworks, Projects, Others 0 0 0
    Mid-term Exams (Written, Oral, etc.) 2 6 12
    Final Exam 1 12 12
Total Workload: 53
Total Workload / 25 (h): 2.12
ECTS Credit: 2