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Course Description Course Name : Physiology Course Code : DEN283 Course Type : Compulsory Level of Course : First Cycle Year of Study : 2 Course Semester : Fall and Spring (32 Weeks) ECTS : 6 Name of Lecturer(s) : Prof.Dr. AYŞE DOĞAN Prof.Dr. ŞEREF ERDOĞAN Asst.Prof.Dr. BESİM ÖZAYKAN Prof.Dr. SANLI SADİ KURDAK Assoc.Prof.Dr. KEREM TUNCAY ÖZGÜNEN Learning Outcomes of the Course : Gain a sound understanding of how human body processes, particularly head, neck, teeth, maxilla and mandible Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : Teach the physiological structure of systems and the innervation,mechanism and normal range of them Course Contents : Functional structure of cell,body fluids compartmen,transport of substances through cell membranes Resting membrane potentials,communication in the cell and other cell,neuron,axon,axonal current Action potential,ionic essential of comminication, molecular mechanism of skeletal muscle contraction and contraction type, sumation,heart and smooth muscle. Erythrocytes,erytropoezis,blood formation,function of leukocytes Development of immun system, humorale and cell immunty,cytokines,lymphokines Blood groups,proteins of blood, platelets and hemostasis Electrical synapses evenst,inhibition, facilitation Chemical transmision of synaptic activity, neuromuscular transmission Special senses organs,start of impulse,reflex arc,tension and polysynaptic reflex Autonomic nervous system,special senses,sense of taste, ,sense of smell Eye and function of vision,,hearing and balance. Motor function of nervous system,intellectual function of nervous system Sleep-wake up mechanism and electrical activity of brain. Exitation of heart muscle and transmission,EKG and essential feature, abnormalty ritm in the heart. Mechanical event of heart cycle,arterial and juguler pulse, output of heart and measurement,other factors. Fluids and haemodynamics,vessels and capillarity, arteial and venous circulation. Capillary circulation ,lympatic and venous circulation,cardiovascular regulatuar mechanism, local regulation of circulation. Systemic regülation mechanism of circulation, cerebral circulation and heart circulation. Special circulation systems, cardiovascular answer to exercise and haemoragical shock, sencop, hypertension and cardiac failure Gas law and mechanics of pulmonary ventilation ,pulmonary volümes and capacities, pulmonary circulatory system,other functions of the pulmonary system. Transport of O2 and CO2 and blood buffered, regulation of breathing,regulation of breathing hypoxi and exercise Energy balance and resting metabolism,termoregülation. Motility:General principles,gastrointestinal tract hormons,motility:swallow,özafagial and gastric motility,vomiting. Gastrointestinal secretion:spit and stomach, motility:small intestine and colon,defecation Gastrointestinal secretion:pancrease,liver, bile,digestion and absorbtion, protein and carbonhidrate. Digestion and absorbtion:Absorption of salt and water,Digestion and absorbtion Ca, Fe, B12 ve lipid,functional organization of kidney and renal filtration. Tubular function,renal blood stream,renal concantration and dilution,regulation water and osmolarity. Renal regülation potassium, calcium,phosphate and acid-base balance. Body metabolism,hormones and effect mechanism, pancreatic hormones. Calcium and bone metabolism,hypotalamus and pituitary hormones, growth physiology and thyroid hormones. Adrenocortical and medullar hormones, pituitary gonodotropins,puberty and menapose Reproductive systems of man and female,pregnancy, labour,prolactine,lactation Language of Instruction : Turkish Work Place : classroom and laboratuary   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Functional structure of cell, body liquid parts, cell membrane transport Assigned handout and book chapter Discussion and oral presentation 2 Rest membrane potential, intra and extracelular communication, neuron, acson, acsonic current Assigned handout and book chapter Discussion and oral presentation 3 Action potential, ionic base of communication, molecular mechanism of muscle contruction, contruction types, hearth and muscles Assigned handout and book chapter Discussion and oral presentation 4 Eritrocytes, eritropoesis, eritropoetin, blood, functions of White blood cells Assigned handout and book chapter Discussion and oral presentation 5 development of immune system, celular immunity, lenfokines, cytokines Assigned handout and book chapter Discussion and oral presentation 6 Blood groups, plasma proteins, trombocytes, hemostasis Assigned handout and book chapter Discussion and oral presentation 7 Electrical events in sinapsis, inhibtion, facilation Assigned handout and book chapter Discussion and oral presentation 8 1st midterm exam. Chemical transfer of sinaptic activity Assigned handout and book chapter Discussion and oral presentation 9 Impulse start, reflection, strain and polysinaptic reflexes Assigned handout and book chapter Discussion and oral presentation 10 Otonom nerve system, taste and smell Assigned handout and book chapter Discussion and oral presentation 11 Eye and its function,Hearing and stability Assigned handout and book chapter Discussion and oral presentation 12 Motor functions of neuron system. and functions of neuron systems Assigned handout and book chapter Discussion and oral presentation 13 Mechanism of sleep and awakeness. Electrical functions of brain. Reflexes and Midterm exam Assigned handout and book chapter Discussion and oral presentation 14 Exication of heart muscle and transport of stimuli, ECG and basic functions. Abnormal rythm of hearth Assigned handout and book chapter Discussion and oral presentation 15 Mechanical events of hearth cycle, hearth noises Assigned handout and book chapter Discussion and oral presentation 16 Liquids and hemodynamics, arteria and capillaries Assigned handout and book chapter Discussion and oral presentation 17 Capiillary system, lenfathic and venous system, cardiovascular regulating mechanisms, local regulation Assigned handout and book chapter Discussion and oral presentation 18 Systemic regulation mechanisms, hearth Assigned handout and book chapter Discussion and oral presentation 19 Particular blood systems, excercise and hemoragic shock, cardiovasculer reply, syncope, hipertension, cardiovasculer reply in hearth deficiency, Assigned handout and book chapter Discussion and oral presentation 20 Gas laws, mechanics of breathing, lungs volüme and capacity, other functions of breath system Assigned handout and book chapter Discussion and oral presentation 21 Blood tamposn, regulation of breath, excercise and hipoxia Assigned handout and book chapter Discussion and oral presentation 22 Energy balance and basal metabolism, thermoregulation, midterm exam Assigned handout and book chapter Discussion and oral presentation 23 Mototite: general principles, gastrointestinal canal and hormones. Mototite: eusopheagus and gastric motility, gaging, Assigned handout and book chapter Discussion and oral presentation 24 Gastrointestinal secration: saliva and stomach, defecation Assigned handout and book chapter Discussion and oral presentation 25 Gastrointestinal secration: pancreas, liver, carbonhydrates and proteins Assigned handout and book chapter Discussion and oral presentation 26 Digestion and absorption. Salt and water absorption. Ca, Fe, B12 and lipids. Functional organisation of renals, renal filtration Assigned handout and book chapter Discussion and oral presentation 27 Tubular function, renal contraction, water and osmolite regulation Assigned handout and book chapter Discussion and oral presentation 28 K, Ca, PO4 homeostasis, acid and base regulation, H secretion, HCO3 reabsorption Assigned handout and book chapter Discussion and oral presentation 29 Complete body metabolism, hormones and effect mechanism, pancreas hormones Assigned handout and book chapter Discussion and oral presentation 30 Ca metabolism and bone, hypothalamus and hypofis hormones, groeth physiology, tiroid hormones Assigned handout and book chapter Discussion and oral presentation 31 surrenel cortex, medulla hormones, hypophis, gonadotropins, puberte, menaposis Assigned handout and book chapter Discussion and oral presentation 32/33/34 Men and women, pregnancy, birth, prolactin, lactation, midterm exam Assigned handout and book chapter Discussion and oral presentation   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  1. Berne MR, Levy NM, Koeppen MB, Stanton BA, Phsiology, 5.edition, 2008 2.Guyton A.C, John E.H. Tıbbi Fizyoloji.10. baskı.London;W.B. Saunders Company, 1987 Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 5 100     Homeworks/Projects/Others 0 0 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Understand the concepts and relationships between concepts in the field of dentistry and have advanced contemporary theoretical and practical knowledge in the field of health care. 4 2 Have the ability to evaluate the nature, resource, limits, accuracy, reliability, and validity of knowledge. 2 3 Have the knowledge of discovering, evaluating and applying scientific information in dental field. 3 4 Be aware of the importance of ethical principles and ethical rules. 1 5 Be able to use advanced theoretical and practical knowledge regarding dentistry on advanced level 4 6 Be able to use the computer programs, related technology and educational tools in dentistry 1 7 Be able to take responsibility, either individually or as a team member, in solving complicated and unpredictable problems related to dental applications 3 8 Be able to critically assess acquired advanced knowledge and skills related to dentistry 3 9 Competent in specifying learning-needs and resources and guid the learning process by using resources effectively 1 10 Capable of developing and internalizing a positive attitude towards lifelong learning 1 11 Be qualified in instructing people or institutions on matters related to dentistry, transferring ideas and solving problems in a written or oral form, receiving thoughts, requirements and expectations of related people and institutions 1 12 Share professional information with both experts and people who are unfamiliar to this field 1 13 Capable of following professional information and interacting with international colleagues using at least one foreign language at European Language Portfolio B1 level 1 14 Be proficient in utilizing information and communication technologies on computer software at least at the level required by the European Computer Driving License in the field of dentistry. 1 15 Able to observe and evaluate contemporary developments in dentistry 1 16 Capable of using verbal and written Turkish language correctly and expressing herself/himself 1 17 Act according to the duties, the laws related to rights and responsibilities, regulations, legislation and professional ethical rules 1 18 Improve continuously in his/her own profession, as well as skills in accordance with scientific, social, cultural and artistic fields by identifying learning needs. 1 19 Have sound information about understanding the healthy and unhealthy invidual´s structure, the physiological functions and behaviors, and the interaction between health and physical and social environment 1 20 Have adequate experience on dental clinical applications 1 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 29 3 87     Out of Class Study (Preliminary Work, Practice) 29 2 58 Assesment Related Works     Homeworks, Projects, Others 0 0 0     Mid-term Exams (Written, Oral, etc.) 5 1 5     Final Exam 1 10 10 Total Workload: 160 Total Workload / 25 (h): 6.4 ECTS Credit: 6