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Course Description Course Name : Molecular Biology Course Code : BL 310 Course Type : Compulsory Level of Course : First Cycle Year of Study : 3 Course Semester : Spring (16 Weeks) ECTS : 3 Name of Lecturer(s) : Prof.Dr. BURHAN ARIKAN Learning Outcomes of the Course : Macromoleculs and DNA analysis Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : BL 310 Molecular Biology Recommended Optional Programme Components : None Aim(s) of Course : Lerning of macromoleculs structures, DNA analysis, DNA repair systems, proteomic, genomic, antisens oligonucleotids, molecular diagnostics Course Contents : Structure and replication of DNA, DNA repcilation enzymes, DNA sequencing, Resctriction endonuclease enzymes, protein isolation techniques and prufication, Techniques of DNA and protein analyses (Agarose gel electrophoresis, PAGE, Isoelectric focusing, two dimensional electrophoresis, gradient PAGE), DNA repair mechanisms (SOS, excision, photoreactivation, post replicative repair), proteomic, genomic, gene therapy, antisense oligonucleotide therapy, recombinant vaccines (Recombinant DNA and viral vaccines) Language of Instruction : Turkish Work Place : Class   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 DNA replication and replication type Study in literature Oral presentation 2 Molecular content of DNA replications Study in literature Oral presentation 3 DNA repcilation enzymes Study in literature Oral presentation 4 DNA sequencing Study in literature Oral presentation 5 Resctriction endonuclease enzymes Study in literature Oral presentation 6 Protein isolation techniques and prufication Study in literature Oral presentation 7 Exam 8 PAGE, SDS-PAGE, two dimensional PAGE, İsoelectric focusing, Immunelectrophoresis Study in literature Oral presentation 9 DNA repair mechanisms (SOS, Exiition, Photoreactivation, Post replicatice repair) Study in literature Oral presentation 10 Antisence oligonucleotide techniques Study in literature Oral presentation 11 Recombinant DNA vaccines Study in literature Oral presentation 12 Recombinant virus vaccines Study in literature Oral presentation 13 Molecular identification techniques (DNA fingerprint, RFLP, RAPD) Study in literature Oral presentation 14 Proteomic, Genomic and gene theraphy Study in literature Oral presentation 15 DNA and protein anaysis techniques (Starch, cellulosa asetate, agarose gel electrophoresis) Study in literature Oral presentation 16/17 Final exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)         Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 40     Homeworks/Projects/Others 2 60 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Develops his/her professional experiences and knowledges by taking elective courses together with basic subjects of biology 2 2 takes responsibility as an individual or in a group to solve unpredicted problems that would be encountered 2 3 plans and manages the projects as a member of team 2 4 informs an indivudual and institutions about the subjects related to biology, and prepare verbal and written presentation to solve the problems 3 5 communicates effectively with colleagues in the world about biological issues and works 1 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 2 28     Out of Class Study (Preliminary Work, Practice) 14 2 28 Assesment Related Works     Homeworks, Projects, Others 2 2 4     Mid-term Exams (Written, Oral, etc.) 1 6 6     Final Exam 1 12 12 Total Workload: 78 Total Workload / 25 (h): 3.12 ECTS Credit: 3