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Course Description Course Name : Bone Marrow Procedures Course Code : PEDO-514 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 1 Course Semester : Spring (16 Weeks) ECTS : 4 Name of Lecturer(s) : Asst.Prof.Dr. GÜLAYSEZGİN Learning Outcomes of the Course : A student learns cellular biology of hematopoiesis A student learns bone marrow aspiration A student gains the ability to collect peripheral stem cells A student gains insight into cord blood stem cells A student gains knowledge on cord blood banks A student gains knowledge on bone marrow and peripheral stem cell donor registries A student learns to process stem cells A student gains knowledge on mesenchymal stem cells A student gains knowledge on autologous stem cells Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : PEDO516,PEDO518,PEDO508,PEDO514,PEDO530 Aim(s) of Course : Students get insight into processing of different stem cell types Course Contents : Processing of different stem cell types,mesenchymal stem cell production Language of Instruction : Turkish Work Place : Lectures will be held in the classroom ,patient bedside, cell culture lab and apheresis unit   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Cellular biology of hematopoiesis Reading relevant articles and book chapters Lecture and Interactive Discussion 2 Mesenchymal stem cells Reading relevant articles and book chapters Lecture and Interactive Discussion 3 Bone marrow aspiration Reading relevant articles and book chapters Bedside applied instruction 4 Peripheral stem cell Reading relevant articles and book chapters Lecture and Interactive Discussion 5 Cord blood stem cells Reading relevant articles and book chapters Lecture and Interactive Discussion 6 Culturing stem cells Reading relevant articles and book chapters Cell culture lab applied instruction 7 Processing of stem cells Reading relevant articles and book chapters Visiting Apheresis Unit 8 Mid-term exam Revision Written and applied exam 9 Placenta derived stem cells Reading relevant articles and book chapters Lecture and Interactive Discussion 10 Induced Pluripotent stem cells Reading relevant articles and book chapters Lecture and Interactive Discussion 11 Cord blood banking Reading relevant articles and book chapters Lecture and Interactive Discussion 12 Donor registries Reading relevant articles and book chapters Lecture and Interactive Discussion 13 Autologous stem cells Reading relevant articles and book chapters Lecture+Visiting Apheresis Unit 14 Future perspectives of stem cells Reading relevant articles and book chapters Interactive Discussion 15 Review of the topics before finals Revision Discussion 16/17 Final exam Revision Written and applied exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Thomas´ Hematopoietic Cell transplantation 4th Ed  Hematopoietic Stem Cell Transplantation in Clinical Practice Jennifer Treleaven A.John Barrett Required Course Material(s)  Foundation For The Accrediation of Cellular Therapy www.factwebsite.org  Bone marrow donor registry www.bonemarrow.org  European Cord Blood Organization www.netcord.org   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 8 50     Homeworks/Projects/Others 15 50 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 A student can explain the basic concepts and principles of bone marrow transplantation 5 2 A student can explain the basic principles of tumor immunology 1 3 A student can explain the basic principles of oncogenesis and its molecular basis 2 4 A student can explain the basic principles of pediatric oncology 1 5 A student can explain the basic principles of tumor biology 2 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 2 28     Out of Class Study (Preliminary Work, Practice) 10 2 20 Assesment Related Works     Homeworks, Projects, Others 15 2 30     Mid-term Exams (Written, Oral, etc.) 8 2 16     Final Exam 8 2 16 Total Workload: 110 Total Workload / 25 (h): 4.4 ECTS Credit: 4