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| Course Description |
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| Course Name |
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Origin and Development of Blood cells |
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| Course Code |
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PEDO-502 |
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| Course Type |
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Compulsory |
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| Level of Course |
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Second Cycle |
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| Year of Study |
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1 |
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| Course Semester |
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Fall (16 Weeks) |
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| ECTS |
: |
4 |
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| Name of Lecturer(s) |
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Prof.Dr. ATİLA TANYELİ
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| Learning Outcomes of the Course |
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A student learns the molecular and cellular mechanisms of hematopoiesis
A student learns stem cell niche
A student learns stem cell model of hematopoiesis
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| Mode of Delivery |
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Face-to-Face |
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| Prerequisites and Co-Prerequisites |
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None |
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| Recommended Optional Programme Components |
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N/A |
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| Aim(s) of Course |
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Students learn the mechanisms in hematopoiesis |
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| Course Contents |
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Cell cycle,Cell signalling,Adhesion molecules,Apoptosis,regulation of hematopoiesis,granulopoiesis,erythropoiesis,thrombocytopoiesis,bone marrow microenvironment,stem cell model of hematopoiesis,dendritic cells,macrophages,mast cells,eosinophils,basophils,B lymphocytes,T lymphocytes |
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| Language of Instruction |
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Turkish |
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| Work Place |
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Classroom |
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Course Outline /Schedule (Weekly) Planned Learning Activities |
| Week | Subject | Student's Preliminary Work | Learning Activities and Teaching Methods |
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1 |
Cell cycle |
Reading book chapters related to the subject |
Lecture and discussion. |
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2 |
Cell signalling |
Reading book chapters related to the subject |
Lecture and discussion. |
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3 |
Adhesion molecules |
Reading book chapters related to the subject |
Lecture and discussion. |
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4 |
Apoptosis |
Reading book chapters related to the subject |
Lecture and discussion. |
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5 |
Regulation of hematopoiesis |
Reading book chapters related to the subject |
Lecture and discussion. |
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6 |
Granulopoiesis |
Reading book chapters related to the subject |
Lecture and discussion. |
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7 |
Eosinophils,basophils and mast cells |
Reading book chapters related to the subject |
Lecture and discussion. |
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8 |
Mid-term exam |
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Written exam |
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9 |
Erythropoiesis |
Reading book chapters related to the subject |
Lecture and discussion. |
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10 |
B lymphocytes |
Reading book chapters related to the subject |
Lecture and discussion. |
|
11 |
T lymphocytes |
Reading book chapters related to the subject |
Lecture and discussion. |
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12 |
Dendritic cells and macrophages |
Reading book chapters related to the subject |
Lecture and discussion. |
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13 |
Thrombocytopoiesis |
Reading book chapters related to the subject |
Lecture and discussion. |
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14 |
Bone marrow microenvironment |
Reading book chapters related to the subject |
Lecture and discussion. |
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15 |
Stem cell model of hematopoiesis |
Reading book chapters related to the subject |
Lecture and discussion. |
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16/17 |
Final exam |
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Written exam |
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Required Course Resources |
| Resource Type | Resource Name |
| Recommended Course Material(s) |
 Basic Principles and Practice of Hematology,Hofman R,Elsevier Churchill Livingstone
Mechanisms in Hematology,Israels Lyonel G,Israels Esther D
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| Required Course Material(s) | |
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Assessment Methods and Assessment Criteria |
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Semester/Year Assessments |
Number |
Contribution Percentage |
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Mid-term Exams (Written, Oral, etc.) |
8 |
50 |
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Homeworks/Projects/Others |
15 |
50 |
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Total |
100 |
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Rate of Semester/Year Assessments to Success |
40 |
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Final Assessments
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100 |
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Rate of Final Assessments to Success
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60 |
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Total |
100 |
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| Contribution of the Course to Key Learning Outcomes |
| # | Key Learning Outcome | Contribution* |
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1 |
A student can explain the basic concepts and principles of bone marrow transplantation |
5 |
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2 |
A student can explain the basic principles of tumor immunology |
5 |
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3 |
A student can explain the basic principles of oncogenesis and its molecular basis |
5 |
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4 |
A student can explain the basic principles of pediatric oncology |
4 |
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5 |
A student can explain the basic principles of tumor biology |
5 |
| * Contribution levels are between 0 (not) and 5 (maximum). |
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| Student Workload - ECTS |
| Works | Number | Time (Hour) | Total Workload (Hour) |
| Course Related Works |
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Class Time (Exam weeks are excluded) |
14 |
2 |
28 |
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Out of Class Study (Preliminary Work, Practice) |
10 |
2 |
20 |
| Assesment Related Works |
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Homeworks, Projects, Others |
15 |
2 |
30 |
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Mid-term Exams (Written, Oral, etc.) |
8 |
2 |
16 |
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Final Exam |
8 |
2 |
16 |
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Total Workload: | 110 |
| Total Workload / 25 (h): | 4.4 |
| ECTS Credit: | 4 |
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