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Course Description Course Name : Biology of Childhood Cancers Course Code : PEDO524 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 1 Course Semester : Spring (16 Weeks) ECTS : 4 Name of Lecturer(s) : Assoc.Prof.Dr. SERHANKÜPELİ Learning Outcomes of the Course : A student learns the formation of cancer in cellular level A student learns the relation between cell cycle and cancer A student learns the mechanisms of angiogenesis and metastasis Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : Students learn about the formation and progression of childhood cancers in cellular level Course Contents : Growth Factors, Signal Transduction, Nuclear Hormones, Stem Cells, Cell Cycle, Apoptosis, Angiogenesis, Metastasis Language of Instruction : Turkish Work Place : Classroom   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Background Reading relevant chapters and articles Interactive discussion 2 Growth Factors Reading relevant chapters and articles Interactive discussion 3 Signal Transduction Reading relevant chapters and articles Interactive discussion 4 Epidermal and Fibroblast Growth Factors Reading relevant chapters and articles Interactive discussion 5 Insulin-like Growth Factor Reading relevant chapters and articles Interactive discussion 6 Platelet-derived Growth Factor Reading relevant chapters and articles Interactive discussion 7 Neurotrophins and their receptors Reading relevant chapters and articles Interactive discussion 8 Mid-term exam Reviewing the lectures Written Exam 9 Nuclear Hormones Reading relevant chapters and articles Interactive discussion 10 Stem Cells Reading relevant chapters and articles Interactive discussion 11 Cell Cycle Reading relevant chapters and articles Interactive discussion 12 Apoptosis Reading relevant chapters and articles Interactive discussion 13 Angiogenesis Reading relevant chapters and articles Interactive discussion 14 Metastasis Reading relevant chapters and articles Interactive discussion 15 Treatments Aimed at Cell cycle and Signal transduction Reading relevant chapters and articles Interactive discussion 16/17 Final exam Reviewing all lectures Written Exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Pizzo PA, Poplack DG (editors). Principles and Practice of Pediatric Oncology. LWW, PA, 2011. Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 8 50     Homeworks/Projects/Others 15 50 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 A student can explain the basic concepts and principles of bone marrow transplantation 1 2 A student can explain the basic principles of tumor immunology 1 3 A student can explain the basic principles of oncogenesis and its molecular basis 5 4 A student can explain the basic principles of pediatric oncology 5 5 A student can explain the basic principles of tumor biology 5 6 A student becomes trained in the field of tumor biology 2 7 A student can apply the basic laboratory techniques 2 8 A student can work in Pediatric Oncology laboratories 3 9 A student understands tumor biology and bone marrow transplantation 5 10 A student can apply methods in an oncology laboratory 2 11 A student acknowledges mechanisms in tumor biology,procedures in blood transfusions and bone marrow transplantation 4 12 A student can develop the necessary skills to communicate with patients 1 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 2 28     Out of Class Study (Preliminary Work, Practice) 10 2 20 Assesment Related Works     Homeworks, Projects, Others 15 2 30     Mid-term Exams (Written, Oral, etc.) 8 2 16     Final Exam 8 2 16 Total Workload: 110 Total Workload / 25 (h): 4.4 ECTS Credit: 4