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Course Description Course Name : Thesis Course Code : BİO-730 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 2 Course Semester : Fall and Spring (16 Weeks) ECTS : 25 Name of Lecturer(s) : Prof.Dr. DAVUT ALPTEKİN Prof.Dr. HALİL KASAP Prof.Dr. MÜLKİYE KASAP Assoc.Prof.Dr. AYFER PAZARBAŞI Prof.Dr. OSMAN DEMİRHAN Prof.Dr. HÜSNÜ ÜMİT LÜLEYAP Learning Outcomes of the Course : Gathers information on any subject to research. Plans a research topic. Designs the research. Forms the background for the project. Finalises researches, does labratory work to get new information. Interprets the results on a scientific basis. Writes a scientific paper with the results. Writes a thesis with the results by himself. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : The purpose of this lecture is to teach students to plan a scientic study , the skills needed to do it by themselves, and to comment on the results. Course Contents : Scanning the current information on molecular and genetics issues, creating a hypothesis, planning the thesis study, collecting the literature related to the thesis study, commenting on the literature and analysing it, preparing the thesis project, forming the background for the project, doing the laboratory work, commenting on the results, commenting on the results and supporting them with literature and writing the thesis through discussion, presenting the thesis in a scientific meeting. Language of Instruction : Turkish Work Place : Seminar room, Laboratory   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Scanning the current information on molecular and genetics issues Literature review Research 2 Creating a hypothesis Literature review Research 3 Planning the thesis study Studying completed theses Research 4 Collecting the literature related to the thesis study Literature review Research 5 Commenting on the results and supporting them with literature Literature review Research 6 Commenting on the results and supporting them with literature Literature review Research 7 Preparing the thesis project Literature review Research 8 Forming the background for the project Literature review Research 9 Doing laboratory work Laboratory trials Laboratory work 10 Doing laboratory work Laboratory trials Laboratory work 11 Doing laboratory work Laboratory trials Laboratory work 12 Summarising and interpreting the results Laboratory trials Research and comment 13 Summarising and interpreting the results Analysis Research and comment 14 Commenting on the results and supporting them with literature and writing the thesis through discussion Writing the thesis Study 15 Commenting on the results and supporting them with literature and writing the thesis through discussion Writing the thesis Study 16/17 Presenting the thesis in a scientific meeting. Completion of the thesis Presentation and thesis defense   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Klug WS, Cummings MR. Genetic Concepts, Sixth Edition. Translation Editor: Öner C., Palme Yayıncılık, 2002.  Cooper GM, Hausman RE. The Cell, Molecular Aproach. Third Editions: Meral Sakızlı, Neşe Atabey. İzmir Tıp Kitabevi, 2006.  Kasap H, Kasap M, Demirhan O, Alptekin D, Lüleyap Ü, Pazarbaşı A, Güzel Aİ. Medical Biology and Genetics. Editor; Halil Kasap, Nobel Tıp Kitabevi, Adana, 2010. Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 0 0     Homeworks/Projects/Others 1 100 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Explains theorical debates of three main areas (philosophy, sociology, psychology) in relation to today´s problems 5 2 Knows the functions of tissues and organ systems. 0 3 Knows the structure of the genetic material. 0 4 Knows the genetic diseases and the genes that cause genetic diseases and disorders. 0 5 Is able to conduct molecular and cytogenetic diagnosis analysis. 2 6 Knows what numerical and structural abnormalities of the autosomes and the sex chromosomes mean and explain them. 0 7 Is able to do DNA isolation from all types of tissue. 5 8 Is able to perform PCR. 5 9 Is able to perform and interpret agarose and polyacrylamide gel electrophoresis. 3 10 Is able to measure the DNA obtained from tissues using a spectrophotometer. 5 11 Is capable of interpreting and implementing QF-PCR technique. 0 12 Is able to cell culture from blood, amniotic, chorionic villus biopsy specimens, and obtain chromosome preparation. 0 13 Is able to recognize and interpret all human chromosomes from the preparations derived from chromosome karyotype analysis. 0 14 Learns how to write and comment on a scientific article. 5 15 Knows the structure of genes. 0 16 Knows the chromosome and gene mutations. 0 17 Knows patterns of inheritance (autosomal dominant, autosomal recessive, sex-linked dominant and recessive inheritance models). 0 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 16 0 0     Out of Class Study (Preliminary Work, Practice) 16 37 592 Assesment Related Works     Homeworks, Projects, Others 1 30 30     Mid-term Exams (Written, Oral, etc.) 0 0 0     Final Exam 0 0 0 Total Workload: 622 Total Workload / 25 (h): 24.88 ECTS Credit: 25