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Course Description Course Name : Cell and tissue biophysics-1 Course Code : BFZ-500 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall (16 Weeks) ECTS : 6 Name of Lecturer(s) : Prof.Dr. İSMAİL GÜNAY Learning Outcomes of the Course : learns membrane structure and membrane models learns generation of membrane potential calculates ionic equilibrium potential using Nernst equation calculates steady-state potential of a cell using GHK equation has ability to apply basic principles learned in biophysical lectures to living systems learns muscle action potential and EMG signals learns physical basis of EKG Learns physical basis of EEG Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : Students explain the bioelectric phenomena in cell, tissue, and organism through the laws of physics and biophysical methods. Course Contents : Membrane potential models, Constant Electricl field Membrane model, Nernst equation, Hodgkin-Huxley-Katz equation, H-H membrane model, electric equivalent network models of membrane, Subthreshold phenomenon, single fiber and fiber bundle action potentials, extracellular and surface potentials, Electromyography, electrocardiography, electroencephalography. Language of Instruction : Turkish Work Place : Classroom, laboratory   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 membrane potential reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 2 Constant electric field membrane model reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 3 Nernst and Hodgkin-Huxley-Katz equations reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 4 Electrical equivalent network model of membrane reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 5 Subthresold phenomena reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 6 Single fiber and nerve bundle action potentials reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 7 Extracellular and surface potentials reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 8 Homework1 reviews related chapters and literature presentation, practice, discussion 9 Surface and volume conductor potentials reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 10 Homework2 reviews related chapters and literature presentation, practice, discussion 11 Electrocardiography reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 12 Homework3 reviews related chapters and literature presentation, practice, discussion 13 Electrocardiography reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 14 Homework4 reads the related chapters in the textbook and reviews the literature presentation, practice, discussion 15 Electroencepholography reads the related chapter beforehand Lecture, class discussion, problem solving, open textbook tests, take home tests 16/17 Final Exam oral and written exam, practice   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Biophysics lecture notes- Problems and practices- Prof Dr Ferit Pehlivan´s Biophysics book  Cellular biophysics-Thomas Fisher Weiss, 1996 Massachusetts Institute of Technology  Ionic Channels of Excitable membranes-Bertil Hille 1992, Sinauer Associates Inc-Sunderland, Massachusettts  Medical Physics Vol 3 Synapse, Neuron, Brain-A.C. Damask, C.E Swenberg 1984, Academic press-London  Textbook of Physiology Vol 1 Excitable Cells and Neurophysiology-H.D Patton, Albert F. Fuchs, Bertil Hille, Allen M. Scher, Robert Steiner 1989 WB Saunders Philadelphia Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 25     Homeworks/Projects/Others 4 75 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Students do an experiment on their own 0 2 Students have analytic notion mechanism related to the field, they are able to have access to reliable knowledge, they are able to design and write a research project , they study depending on ethical values 1 3 Students are able to systematically impart the theoretical knowledge that is being investigated to the audience effectively and transfer it to public 1 4 Students are able to report the results of a research 2 5 Students are able to interpret the findings of a research 3 6 Students have scientific consideration related to the profession 3 7 Students do an experimental setup in the laboratory and study on it 3 8 Students plan an experimental research 2 9 Students get basic knowledge of the specialiity 5 10 Students prepare a project proposal by themselves 0 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 4 56     Out of Class Study (Preliminary Work, Practice) 14 3 42 Assesment Related Works     Homeworks, Projects, Others 4 10 40     Mid-term Exams (Written, Oral, etc.) 1 5 5     Final Exam 1 5 5 Total Workload: 148 Total Workload / 25 (h): 5.92 ECTS Credit: 6