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Course Description Course Name : Phase II-Normal Structure and Function/Systems Course Code : MED200 Course Type : Compulsory Level of Course : First Cycle Year of Study : 2 Course Semester : Fall and Spring (52 Weeks) ECTS : 60 Name of Lecturer(s) : Assoc.Prof.Dr. NESLİHAN BOYAN Prof.Dr. ÖZKAN OĞUZ Prof.Dr. FATİH KÖKSAL Prof.Dr. İSMAİL GÜNAY Prof.Dr. NAFİZ BOZDEMİR Assoc.Prof.Dr. ESRA SAATÇI Assoc.Prof.Dr. EMİNE DÖNDÜ KIZILKANAT Asst.Prof.Dr. BESİM ÖZAYKAN Prof.Dr. MEHMET AKİF ÇÜRÜK Prof.Dr. ZELİHA NAZAN ALPARSLAN Prof.Dr. MEHMET MACİT İLKİT Assoc.Prof.Dr. KEREM TUNCAY ÖZGÜNEN Prof.Dr. AKGÜN YAMAN Prof.Dr. BEHİCE DURGUN Prof.Dr. ABDULLAH TULİ Prof.Dr. SAİT POLAT Prof.Dr. FÜGEN YARKIN Prof.Dr. SANLI SADİ KURDAK Prof.Dr. LEVENT KAYRIN Prof.Dr. ŞEREF ERDOĞAN Assoc.Prof.Dr. ŞEYDA ERDOĞAN Prof.Dr. ÖZGÜL TAP Prof.Dr. İSMAİL SONER KOLTAŞ Prof.Dr. AYŞE DOĞAN Prof.Dr. MEMDUHA GÜLHAL BOZKIR Prof.Dr. UFUK ÖZGÜ METE Assoc.Prof.Dr. PINAR KARAKAŞ Prof.Dr. MUSTAFA EMRE Prof.Dr. SUZAN ZORLUDEMİR Prof.Dr. HÜSEYİN REFİK BURGUT Asst.Prof.Dr. ARBİL AÇIKALIN AVCI Assoc.Prof.Dr. H.TURGUT ELBEK ÖZER Prof.Dr. GÜLFİLİZ GÖNLÜŞEN Prof.Dr. MELEK ERGİN Prof.Dr. MUSTAFA YILMAZ Prof.Dr. ERGİN ŞİNGİRİK Prof.Dr. SERPİL ÖNDER Prof.Dr. AYSUN HATİCEUĞUZ Prof.Dr. EREN ERKEN Prof.Dr. YUSUF KARATAŞ Prof.Dr. NURAN ÖĞÜLENER Assoc.Prof.Dr. GÜLGÜN BÜYÜKDERELİ Assoc.Prof.Dr. EDA KUMCU KARABAL Assoc.Prof.Dr. MEHMET ATA SEÇİLMİŞ Prof.Dr. MÜLKİYE KASAP Prof.Dr. FAZİLET AKSU Prof.Dr. ZEYNEP DOĞRUCA YAPAR Prof.Dr. CANDAŞ TUNALI Prof.Dr. MELEK KÖKSAL ERKİŞİ Prof.Dr. OSMAN DEMİRHAN Asst.Prof.Dr. EMİNEKILIÇ BAĞIR Prof.Dr. NURTEN DİKMEN Prof.Dr. SÜLEYMAN ÖZBEK Prof.Dr. DERYA GÜMÜRDÜLÜ Prof.Dr. FİGEN DORAN Prof.Dr. HÜSNÜ ÜMİT LÜLEYAP Assoc.Prof.Dr. TAMER C. İNAL Asst.Prof.Dr. HÜLYAÖZGÜR Learning Outcomes of the Course : Obtain knowledge on the normal embryological development Explain the structure and function of nervous system 3. Explain the structure and function of circulatory and respiratory systems Explain the structure and function of digestive system 6. Able to explain anatomy of the urogenital system, the development and histology, reproductive and excretory physiology. Explain the structure and function of urogenital system Grasp the basic patological concepts underlines the diseases Know the place of genetics in medicine, and application areas of clinical genetics Define flora, and gain knowledge on microbial and parasitary diseases Explain the general terms of pharmacology Explain the general terms of research and gain scientific persvective Conduct research towards being a better physician Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : MED100 Phase I- Normal Structure and Function/ Cell-Tissue, Human Sciences Recommended Optional Programme Components : None Aim(s) of Course : Gain required information regarding structure and function of the body, host-microorganism relations and knowledge and skills that would be the foundation of clinical sciences on the basis of organ systems. Course Contents : Provides the integration of basic and clinical sciences, professional skills laboratory practices, health education practices, board consists of five courses enriched with visits to institutions. The first four course committee includes (nervous system, respiratory- circulation systems, digestion- excretion systems, endocrine- reproductive systems) a training program described in the normal structure and function. In the last course module on cell and tissue injury the basics of general pathology, physiopathology, pharmacology and clinical courses will be introduced. Language of Instruction : Turkish Work Place : Lecture Hall, laboratory   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Gross anatomy of the nervous system, the normal flora and bacteria, first step health care and the concept of health care team, biological systems information, receptors and psychophysics, synapse models and synaptic potentials, electrical synapses events, Introduction to human embryology, gametogenesis. Preparatory work for the course Lecture Hall, laboratory practices 2 able to show the normal flora, Internal structure of the anatomy of the nervous system, neurotransmitters and brain chemistry, inhibitory synapses, facilitation and chemical transmission sensory organs, impulses begin, bacteriology, ovulation and implantation, IVF and microenjection, bioistatistic research, data, sources of health data, HES as a source of health data, patient handling ability. Preparatory work for the course Lecture Hall, laboratory practices 3 Anatomy of the internal structure of the nervous system, sensory organs, the start of impulses, the reflex arc, stretching reflex, reflexes, and reflexes are polysynaptic general characteristics, general sensory system and pain, chemical senses: taste and odor, trilaminary and bilaminary germ disc, embryonic and fetal period, bacteriology , HES as a source of health information, patient handling ability. Preparatory work for the course Lecture Hall, laboratory practices 4 Anatomy of the internal structure of the nervous system, extra-embryonic formations and congenital malformations of the central nervous system histology of the nervous system and muscle activity of the co-ordination of motor function, EEG and evoked potentials, bacteriology Preparatory work for the course Lecture Hall, laboratory practices 5 Integration systems nervous system, central nervous system Histology and Embryology of the autonomic nervous system and the central regulation of the sleep-wake, mechanisms of the brain electrical activity, and the identification of the data summary, as a source of health data HES, patient handling ability. Preparatory work for the course Lecture Hall, laboratory practices 6 The physiological basis of emotions (limbic system) and monoaminergic systems, anatomy and histology of the ear, hearing and balance anatomy, physiology and biophysics, eye anatomy, histology and physiology of the visual pathways, function, and biophysics of the nervous system vessels. Preparatory work for the course Lecture Hall, laboratory practices 7 Eye and vision function, higher cerebral functions. Nervous system integrated Session. Nervous System Practice Exam Committee Preparatory work for the course Lecture Hall, laboratory practices 8 Holidays Lecture Hall, laboratory practices 9 Nervous System Examination Committee written examination Physiology and histology of the cardiovascular system, thorax anatomy, introduction to parasitology and bacteriology. Preparatory work for the course Lecture Hall, laboratory practices 10 Heart anatomy, histology and physiology, ECG and physical fundamentals, nasal anatomy, circulatory system and respiratory system associated with the protozoa, helminths, and parasites, bacteriology. Preparatory work for the course Lecture Hall, laboratory practices 11 Mechanical events in the heart cycle, heart sounds, and measurement of cardiac output, heart beat regulation, vascular bed and fluidized hemodynamic, larynx anatomy and blood parasitizing RES sporozoa, bacteriology, visit to the institution. Preparatory work for the course Lecture Hall, laboratory practices 12 Vascular bed and fluid hemodynamics, arterial system and capillary circulation, hydrostatic pressure, edema, varicose veins blood relationship, Laplace´s law and the aneurysm, Bernoulli´s principle, Poiseuille law and the blood stream, lymphatic and venous circulation, the upper and lower respiratory tract anatomy and histology, the free living amoebae, microspors, bacteriology, distributions. Preparatory work for the course Lecture Hall, laboratory practices 13 Embryology of respiratory systems, physiology and related infectious agents, internal organs, settled cestodes, anaerobic spore-forming bacteria, and free of spores, distributions, statistical evaluation of a single research group, the ability to get your heart rate, body temperature and blood pressure measurement, measurement skills. Preparatory work for the course Lecture Hall, laboratory practices 14 Cardiac and respiratory function tests (blood gas, etc.), exercise, and cardiovascular responses to hemorrhagic shock, cerebral circulation, fetal circulation, bacteriology, trematodes, distributions, statistical evaluation of a single research group, the ability to get your heart rate, body temperature and blood pressure measurement, measurement skills. Preparatory work for the course Lecture Hall, laboratory practices 15 Exercise Biochemistry, buffer systems in the blood, fainting, hypertension, and heart failure, cardiovascular homeostasis in the blood buffer systems. Regulation of pulmonary circulation and respiration, bacteriology, trematodes, circulatory and respiratory physiology and biophysics laboratory applications, distributions, statistical evaluation of a single research group, the ability to get your heart rate, body temperature and blood pressure measurement, measurement skills. Integrated on the circulatory and respiratory system session. Preparatory work for the course Lecture Hall, laboratory practices 16 Acid-base regulation in an organism, exercise and different environmental conditions, respiration, blood, tissues, and body cavity parasites, parasites oncogenic, circulatory and respiratory physiology and biophysics laboratory applications. Preparatory work for the course Lecture Hall, laboratory practices 17 Circulatory-respiratory system, the practical and written exams. 18 The digestive system anatomy, histology-embryology and physiology of protozoa associated with the digestive system, a two-group statistical evaluation of research. Preparatory work for the course Lecture Hall, laboratory practices 19 The digestive system anatomy, histology and physiology, of the gastrointestinal system’s parasitosis and spores, relationships between the variables, a two-group statistical evaluation of research, the ability to apply nasogastric tube and its removal. Preparatory work for the course Lecture Hall, laboratory practices 20 Gastrointestinal system anatomy, histology, physiology, biochemistry, and parasitology, herpes viruses, two-group statistical evaluation of research, the ability to apply nasogastric tube and its removal. Preparatory work for the course Lecture Hall, laboratory practices 21 Gastrointestinal system anatomy, histology-embryology, physiology, biochemistry, and Parasitology, viruses, two-group statistical evaluation of research, the ability to apply nasogastric tube and its removal.Integrated session with the digestive system. Preparatory work for the course Lecture Hall, laboratory practices 22 Semester holiday 23 Semester holiday 24 Urinary system anatomy, histology and physiology of the digestive system, nematodes, flukes, viruses, statistical evaluation of the two-group studies, relationships between variables, male and female urinary catheter insertion-removal ability. Preparatory work for the course Lecture Hall, laboratory practices 25 Hunger and satiety biochemistry, OGTT, hepatitis viruses, slow virus infections, kidney biochemistry and physiology, statistical evaluation of the two-group studies, relationships between variables, male and female urinary catheter insertion-removal ability Preparatory work for the course Lecture Hall, laboratory practices 26 Renal physiology and biochemistry, fluid and electrolyte balance, urinary biochemistry and viruses, parasites settled in the urogenital system, two-group statistical evaluation of research relationships between the variables, male and female urinary catheter insertion-removal ability. Urinary system integrated on the session. Preparatory work for the course Lecture Hall, laboratory practices 27 Acid-base regulation, Pox virus and human papilloma virus, digestive-excretory system teaching practical and theoretical examinations board. Preparatory work for the course Lecture Hall, laboratory practices 28 Endocrine system anatomy, histology and biochemistry. Mycoses. Whole body metabolism, exercise physiology. Preparatory work for the course Lecture Hall, laboratory practices 29 Endocrine histology, physiology and biochemistry. Calcium-phosphate regulatory hormones. Mycoses. Biological effects of X-rays mechanism and bioelectric observation tools. Preparatory work for the course Lecture Hall, laboratory practices 30 Anatomy and histology of the reproductive system. Biochemistry and physiology of the endocrine system. Mycoses. Radioactivity, radiation protection, BT and MRI. Preparatory work for the course Lecture Hall, laboratory practices 31 Reproductive system anatomy, histology-embryology and physiology. Gastrointestinal hormones, biochemistry of sex hormones, kidney, heart and endocrine functions of the pineal gland, thermoregulation, sex differentiation and development. Mycoses. Health education applications Preparatory work for the course Lecture Hall, laboratory practices 32 Physiology and biochemistry of the reproductive system. Biochemistry of pregnancy. Pregnancy, fetal, and neonatal physiology of aging, regulation of food intake, leptin, and other hormones, biochemistry, PET and gamma camera, ultrasound, doppler, and echocardiogram, biophysics applications. Preparatory work for the course Lecture Hall, laboratory practices 33 Endocrine and Reproductive System Practice Exams Committee. Reproductive Health Module Preparatory work for the course Interactive education 34 Endocrine and Reproductive System Written Examination Committee Preparatory work for the course Lecture Hall, laboratory practices 35 Cell and tissue pathology. Mechanisms and pathology of immune deficiency. Medical research methods, decision-making diagnosis. Health education applications. Preparatory work for the course 36 Cell and tissue pathology. Biochemical changes in cellular damage. The pathogenesis of immunodeficiency and classification, Type I hypersensitivity reactions. The definition of inflammation, acute and chronic inflammation, inflammation of vascular and cellular changes, regeneration. General concepts of pharmacology, drug distribution, application areas, and the passage of the biological membrane, otokoids. Medical research methods, decision-making diagnosis. Suturing skills. Health education applications. Preparatory work for the course Lecture Hall, laboratory practices 37 Acute phase reactants, complement system diseases, HLA and transplant immunology. Cell markers and adhesion molecules. Amyloidosis, fluid and electrolyte balance, congestion, edema, hyperemia and hemorrhage. Pathogenesis and pathology of thrombosis. Introduction to neoplasia, the definition and classification of tumors. Mechanisms of drug action, pharmacodynamic interactions. Plasma enzymes. Medical research methods, decision-making diagnosis. Suturing skills. Preparatory work for the course Lecture Hall, laboratory practices 38 Medical Genome Project, genetic disorders, genetic counseling. Features of benign and malignant tumors. And the molecular basis of tumor biology. Chemical and physical carcinogenesis, radiation pathology. Biochemical effects of environmental factors. Antibiotics. Medical research methods, decision-making diagnosis. Suturing skills. Health education applications Preparatory work for the course Lecture Hall, laboratory practices 39 Environmental pathology of diseases. Metabolic processes in the formation of pathological and molecular methods in the diagnosis of cancer. Viral carcinogenesis, tumor invasion and metastasis mechanisms, biology of tumor growth. Tumor kinetics. Cellular and tissue effects of radiation. Bacteria. Pharmacokinetic interactions and factors altering drug metabolism, and their effects. Genetic screening of populations. Preparatory work for the course Lecture Hall, laboratory practices 40 Devices using radiation energy and its principles. Immunopathology of tumor. Tumors of infants and children. Pathology of vitamin deficiencies. Pharmacogenetics. Preparatory work for the course Lecture Hall, laboratory practices 41 YEAR-END FINAL EXAMS   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Dere F. Anatomi Atlası ve Ders Kitabı.  Sobotta Anatomi Atlası.  Netter Anatomi Atlası. Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 5 100     Homeworks/Projects/Others 0 0 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Describes the normal human body and mental structure, function and interaction in all stages of life. 5 2 Explains and sequences common physical and mental disorders-diseases’ epidemiology, pathology, symptoms, signs, prognosis, and treatments. 2 3 Has the knowledge of ethical principles and preventive medicine methods about creating conditions for healthy living and disease prevention. 1 4 Defines common diseases in our country by selecting current, reliable diagnostic methods and appropriate pharmacological, physical, nutritional, psychosocial treatment methods. 3 5 Understands, analyzes and evaluates health and illness components, process and result, uses the evidence-based methods and updated information in the treatment of patients. Adopts the principle of making a decision by evaluating prevailing evidence of the patient’s choice, and self-experiences. 0 6 Takes accurate, comprehensive and problem focused anamnesis, with a systematic approach to the individual makes physical examination and mental evaluation, decides by paying respect to patient privacy, secrets, honor, faith, cultural differences, sexual orientation. 0 7 In cases that requires emergency response such as significant function and loss of an organ; offers first aid and basic life support and plans the next process. 3 8 Makes differential diagnosis by approaching holistically to the patient, has the skills and competence of rational diagnosis and treatment planning, information about patient and disease management, as an individual and team member takes responsibility for unexpected circumstances, monitors and embraces the patient. 0 9 Makes Individual, family and community oriented health education, executes the field of work as an individual or as a team member, makes counseling, supervision, expertise, leadership. 0 10 Within the framework of the project which will be conducted, plans, manages the staff development of the team and their education, monitors the process and evaluates, works in partnership with other disciplines. 0 11 Develops a positive attitude towards lifelong learning and behavior, adopts the universal conditions required by the profession of medicine. 3 12 Improves self in cultural, artistic and social fields constantly as well as professional development, plays a part in social responsibility projects with other professional groups. 0 13 Has the ability to communicate intercultural, effectively communicates with patients, coworkers and other parts of the community, and supports ideas and suggestions for solutions with qualitative and quantitative data, transfers verbally and in writing by using Turkish correctly. 3 14 Have the philosophy of science, the limits and the accuracy of the knowledge, validity and reliability of the information, knows how to access information and evaluates information by using critical thinking skills, determines the learning needs and resources related to medicine, directs the learning by using the resources effectively. 0 15 Uses medical informatics and communication technologies along with computer software in required level in the field. 4 16 Understands socio-economic effects of health along with the social and behavioral aspects, by using at least one foreign language European Language Portfolio B1 level monitors information and progress in the field and communicates with colleagues. 0 17 Keeps accurate and reliable records, collects data, analyzes, deciphers epidemic, clinical and laboratory data and acts in accordance with ethical principles in the sharing of the results. 0 18 Bears susceptibility and responsibility in the subject of self-mental and physical health, workers´ health, labor and environment safety, individual and public health, becomes role model to society by developing professional attitude. 0 19 Knows the basic health care legislation, as an individual acts in accordance with regulations, laws, legislations and ethical rules about rights and responsibilities. 0 20 Uses professional autonomy, has sufficient experience to carry out preventive medicine service and capable of doing clinical applications in national and international standards. 0 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 35 30 1050     Out of Class Study (Preliminary Work, Practice) 35 8 280 Assesment Related Works     Homeworks, Projects, Others 0 0 0     Mid-term Exams (Written, Oral, etc.) 5 25 125     Final Exam 1 40 40 Total Workload: 1495 Total Workload / 25 (h): 59.8 ECTS Credit: 60