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Course Description Course Name : Mitochondrial DNA Demages and Its Pathogenesis Course Code : BY-725 Course Type : Optional Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall (16 Weeks) ECTS : 6 Name of Lecturer(s) : Prof.Dr. HASAN BASRİ İLA Learning Outcomes of the Course : Has information about mitochondrial diseases Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : Mitochondria genome and genome-related diseases. Course Contents : Diseases due to impaired mitochondria. Language of Instruction : Turkish Work Place : Classroom   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 The structure of the mitochondria and mtDNA General theoretical preparation Oral and visual presentation 2 Maternal inheritance of mtDNA General theoretical preparation Oral and visual presentation 3 The mechanism of the formation of reactive oxygen species and its varieties General theoretical preparation Oral and visual presentation 4 Stimulation of the antioxidant system General theoretical preparation Oral and visual presentation 5 mtDNA mutation frequency, causes and types of mutation General theoretical preparation Oral and visual presentation 6 mtDNA mutation-induced syndromes General theoretical preparation Oral and visual presentation 7 mtDNA mutation-induced syndromes General theoretical preparation Oral and visual presentation 8 Homework preparation General theoretical preparation Scanning and review 9 Homework preparation General theoretical preparation Scanning and review 10 Homework preparation General theoretical preparation Scanning and review 11 Homework preparation General theoretical preparation Scanning and review 12 Homework preparation General theoretical preparation Scanning and review 13 Homework preparation General theoretical preparation Scanning, analysis, and writing 14 Homework preparation General theoretical preparation Writing and presentation. 15 Homework presentation General preparation Presentation   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Mitochondria in Pathogenesis (2001), Lemasters and Nieminen. Kluwer Academic / Plenum Publishers, New York. Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 0 0     Homeworks/Projects/Others 8 100 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Has the advanced hypothetical and applied knowledges in biology field 4 2 Based on the bachelor´s level of qualification, develops and deepens the knowledge as a specialist in the biology 5 3 Uses the theoretical and practical knowledge he expertises in biology 5 4 Integrates and interprets the knowledge from different disciplines by his expertise in biology and generates new information. 4 5 Solves the problems of biology by using research methods. 3 6 Carries out an independent study requires expertise on biology 2 7 Develops and produces new strategic approaches and solves the unexpected problems in biology area by taking responsibilty 4 8 Assesses the knowledge he expertises through critical approach and makes leadership solving problems related to biological environments. 3 9 Systematically transfers the current developments in the field of biology and his/her studies to the person in biology field or other related fields by supporting qualitative and quantitative data 5 10 Uses at least one foreign language to keep up to date with the field to take part in scientific and social interaction groups to share information at international levels 5 11 Uses information and communication technologies as required in the biology field 2 12 In biology, uses statistical software programme to carry out scientific research and also uses information and communication technology in proficiency level of knowledge and skills to critically evaluate 2 13 Develops the strategy, policy and implementation plans in the issues related to the field of biology and treats the results obtained within standart of quality 2 14 Uses the knowledge, problem solving, and / or practical skills obtained in the Biology Field in interdisciplinary studies. 4 15 Oversees social, scientific, cultural and ethical values in order to collect, implement, interpret data in the Biology area 3 16 Has the ability to formulate and solve the problems of biology in advanced level 0 17 Has ability to use his advanced knowledge in biology field for thinking systematically and solve problems in multidisciplinary approaches 0 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 15 3 45     Out of Class Study (Preliminary Work, Practice) 15 4 60 Assesment Related Works     Homeworks, Projects, Others 8 3 24     Mid-term Exams (Written, Oral, etc.) 0 0 0     Final Exam 1 15 15 Total Workload: 144 Total Workload / 25 (h): 5.76 ECTS Credit: 6