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Course Description Course Name : Practical Immunology Course Code : TİM-505 Course Type : Optional Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall and Spring (16 Weeks) ECTS : 5 Name of Lecturer(s) : Prof.Dr. AKGÜN YAMAN Learning Outcomes of the Course : Describes the terms of affinity and avidity . Explains the characteristics of antigen-antibody reactions . Is able to make dilutions. Defines the terms of prezone,optimal zone and postzone and also their importance . Uses the agglutination tests for diagnosis of infections. Describes and practises precipitation test tecnique. Is able to perform some tests such as IHA and TPHA and use them to diagnose various diseases. Describes the kinds of ELISA techniques and how they are done and uses them to diagnose infections. Defines the types of fluorescence antibody tests and uses them in diagnosis. Knows the types of RIA and how to do the test. Also explains the use of the test in the diagnosis of diseases . Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : TİM-501 Basic Immunology KMB-502 Diagnostic Microbiology Recommended Optional Programme Components : None Aim(s) of Course : To get basic knowledge about immunolgical test methods and their use in the diagnosis of diseases. Course Contents : Basic terms related to antibodies and using immunological tests involving antibodies are explained through theoretical lessons and practices. Language of Instruction : Turkish Work Place : C.U Faculty of Medicine Department of Medical Microbiology meeting room and laboratories.   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Affinity-Avidity Reading resources and lecture notes on the subject Verbal lecture 2 Characteristics of antigen-antibody reactions Reading resources and lecture notes on the subject Verbal lecture 3 Dilution Reading resources and lecture notes on the subject Verbal lecture, presentation 4 The terms of prezone, optimal zone, post zone Reading resources and lecture notes on the subject Verbal lecture, presentation 5 Agglutination tests Reading resources and lecture notes on the subject Verbal lecture, presentation 6 Precipitation tests Reading resources and lecture notes on the subject Verbal lecture 7 Agglutination reactions including erythrocyte ( IHA, TPHA etc.) Reading resources and lecture notes on the subject Verbal lecture, presentation 8 Midterm exam Exam Preparation Written Exam 9 ELISA Reading resources and lecture notes on the subject Verbal lecture, presentation 10 Fluorescence antibody Reading resources and lecture notes on the subject Verbal lecture, presentation 11 RIA Reading resources and lecture notes on the subject Verbal lecture, presentation 12 Practise Laboratory preparation Laboratory 13 Practise Laboratory preparation Laboratory 14 Practise Laboratory preparation Laboratory 15 Lecture overwiev None Verbal lecture,discussion 16/17 Final exam Exam preperation Practical exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Delves PJ, Martin SJ, Burton DR, Roitt IM, Translation editor: Ilıman MN, Assistant editor:Yıldız M, Temel İmmünoloji. Atlas Booktrade 2008  Male D, Brostoff J, Roth DB, Roitt I, Immunology. seventh edition Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 60     Homeworks/Projects/Others 2 40 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Identifies morphological and physiological characteristics of microorganisms 2 2 Identificates genomic structures of microorganisms 2 3 Explains microorganisms virulance factors and infection mechanisms. 3 4 Defines the mechanisms of immune response and defense against microorganisms 5 5 Lists the antimicrobial agents. 3 6 Defines the mechanisms of resistance development against antimicrobial agents. 3 7 Lists the microscopy, culture, serological and molecular diagnostic principles used in the laboratory diagnosis of infectious microorganisms. 5 8 Lists microbiological tests for identification of microorganisms 5 9 Implements and applies the methods used in the period from receipt of the clinical specimens up to identification of the causative agent . 5 10 Prepares a suitable media, applicates the staining methods, biochemical tests and molecular diagnostic methods to identify microorganisms from clinical samples. 5 11 Applies the biochemical tests and basic microbiological staining methods which are necessary for microbiological identification . 5 12 Determines the microorganisms by using basic molecular diagnostic techniques. 2 13 Works individually or as a team member related to the field. 5 14 Carries out the missions given within the scope of research projects. 5 15 Develops a positive attitude and behaviour towards lifelong learning. 4 16 Evaluates own knowledge and new-learned knowledge in a critical view after graduating. 4 17 Communicates effectively. 4 18 Transfers their own ideas and developments in the field, and offers solutions visually and verbally supporting with qualitative and quantitative data. 4 19 Applies ethical principles during study, evaluation and result sharing. 5 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 5 70     Out of Class Study (Preliminary Work, Practice) 14 3 42 Assesment Related Works     Homeworks, Projects, Others 2 3 6     Mid-term Exams (Written, Oral, etc.) 1 5 5     Final Exam 1 10 10 Total Workload: 133 Total Workload / 25 (h): 5.32 ECTS Credit: 5