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| Course Description |
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| Course Name |
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Antigens |
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| Course Code |
: |
TİM-503 |
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| Course Type |
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Optional |
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| Level of Course |
: |
Second Cycle |
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| Year of Study |
: |
1 |
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| Course Semester |
: |
Fall and Spring (16 Weeks) |
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| ECTS |
: |
4 |
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| Name of Lecturer(s) |
: |
Prof.Dr. AKGÜN YAMAN
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| Learning Outcomes of the Course |
: |
Describes the factors affecting the immunological degree of antigen.
Defines the terms of synthetic and semi-synthetic antigens.
Explains the terms of epitope, paratope and hapten and their characteristics.
Specifies types of antigens(hetero antigens,alloantigens, autoantigens, heterophil antigens).
Is able to explain the organs involved in the immune response.
Explains the roles of macrophages,mononuclear phagocytes,lymphocytes,natural killer cells,mast cells,leukocytes and thrombocytes in immune response.
Explains the roles of histocompatibility antigens in immune response.
Is able to describe MHC class I,II,III reigions and claassical MHC antigens.
Clarifies interleukins, interpherons, tumor necrose factors and chemotactic factors.
Explains the importance of membrane receptors for antigens.
Defines B and T cell surface receptors.
Explains the organization of receptors and the term somatic mutation.
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| Mode of Delivery |
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Face-to-Face |
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| Prerequisites and Co-Prerequisites |
: |
TİM-501 Basic Immunology
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| Recommended Optional Programme Components |
: |
None |
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| Aim(s) of Course |
: |
To explain how humoral and cellular immune response occurs. |
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| Course Contents |
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In this lesson, antigen and varieties of antigens, cells and organs responsible for immune response, MHCs, histocompatibility antigens and receptors are taught through teorical and visual methods.
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| Language of Instruction |
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Turkish |
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| Work Place |
: |
C.U Faculty of Medicine Department of Medical Microbiology meeting room |
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Course Outline /Schedule (Weekly) Planned Learning Activities |
| Week | Subject | Student's Preliminary Work | Learning Activities and Teaching Methods |
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1 |
Factors that effect immunological degree of antigen |
Reading resources and lecture notes on the subject |
Verbal lecture, discussion |
|
2 |
Chemical structure of antigens and their relations with antibodies |
Reading resources and lecture notes on the subject |
Verbal lecture |
|
3 |
The terms of epitope,paratope and hapten |
Reading resources and lecture notes on the subject |
Verbal lecture, presentation |
|
4 |
The types of antigens |
Reading resources and lecture notes on the subject |
Verbal lecture |
|
5 |
The organs in the immune response
|
Reading resources and lecture notes on the subject |
Verbal lecture |
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6 |
The cells in the immune response |
Reading resources and lecture notes on the subject |
Verbal lecture,presentation |
|
7 |
The other blood cells |
Reading resources and lecture notes on the subject |
Verbal lecture, presentation |
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8 |
Midterm exam |
exam preperation |
written exam |
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9 |
Histocompatibility antigens |
Reading resources and lecture notes on the subject |
Verbal lecture, presentation |
|
10 |
Classical MHC antigens |
Reading resources and lecture notes on the subject |
Verbal lecture, presentation |
|
11 |
Relationships between cells in immune response
Cytokines |
Reading resources and lecture notes on the subject |
Verbal lecture |
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12 |
Membrane receptors for antigens |
Reading resources and lecture notes on the subject |
Verbal lecture, presentation |
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13 |
T and B cell receptors for antigens |
Reading resources and lecture notes on the subject |
Verbal lecture, presentation |
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14 |
Difference in antigen recognization |
Reading resources and lecture notes on the subject |
Verbal lecture |
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15 |
Evaluation of course term |
none |
Discussion |
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16/17 |
Final exam |
Exam preperation |
Written exam |
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Required Course Resources |
| Resource Type | Resource Name |
| Recommended Course Material(s) |
 Delves PJ, Martin SJ, Burton DR, Roitt IM, Translation editor: Ilıman MN, Aassistant editor: Yıldız M, Temel İmmünoloji. Atlas booktrade. 2008
Male D, Brostoff J, Roth DB, Roitt I, Immunology. seventh edition
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| Required Course Material(s) | |
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Assessment Methods and Assessment Criteria |
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Semester/Year Assessments |
Number |
Contribution Percentage |
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Mid-term Exams (Written, Oral, etc.) |
1 |
60 |
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Homeworks/Projects/Others |
1 |
40 |
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Total |
100 |
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Rate of Semester/Year Assessments to Success |
40 |
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Final Assessments
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100 |
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Rate of Final Assessments to Success
|
60 |
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Total |
100 |
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| Contribution of the Course to Key Learning Outcomes |
| # | Key Learning Outcome | Contribution* |
|
1 |
Identifies morphological and physiological characteristics of microorganisms |
3 |
|
2 |
Identificates genomic structures of microorganisms |
2 |
|
3 |
Explains microorganisms virulance factors and infection mechanisms. |
4 |
|
4 |
Defines the mechanisms of immune response and defense against microorganisms |
5 |
|
5 |
Lists the antimicrobial agents. |
2 |
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6 |
Defines the mechanisms of resistance development against antimicrobial agents. |
2 |
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7 |
Lists the microscopy, culture, serological and molecular diagnostic principles used in the laboratory diagnosis of infectious microorganisms. |
1 |
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8 |
Lists microbiological tests for identification of microorganisms |
1 |
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9 |
Implements and applies the methods used in the period from receipt of the clinical specimens up to identification of the causative agent . |
1 |
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10 |
Prepares a suitable media, applicates the staining methods, biochemical tests and molecular diagnostic methods to identify microorganisms from clinical samples. |
1 |
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11 |
Applies the biochemical tests and basic microbiological staining methods which are necessary for microbiological identification . |
1 |
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12 |
Determines the microorganisms by using basic molecular diagnostic techniques. |
1 |
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13 |
Works individually or as a team member related to the field. |
2 |
|
14 |
Carries out the missions given within the scope of research projects. |
3 |
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15 |
Develops a positive attitude and behaviour towards lifelong learning. |
5 |
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16 |
Evaluates own knowledge and new-learned knowledge in a critical view after graduating. |
5 |
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17 |
Communicates effectively. |
5 |
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18 |
Transfers their own ideas and developments in the field, and offers solutions visually and verbally supporting with qualitative and quantitative data. |
4 |
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19 |
Applies ethical principles during study, evaluation and result sharing. |
5 |
| * Contribution levels are between 0 (not) and 5 (maximum). |
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| Student Workload - ECTS |
| Works | Number | Time (Hour) | Total Workload (Hour) |
| Course Related Works |
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Class Time (Exam weeks are excluded) |
14 |
3 |
42 |
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Out of Class Study (Preliminary Work, Practice) |
14 |
2 |
28 |
| Assesment Related Works |
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Homeworks, Projects, Others |
1 |
3 |
3 |
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Mid-term Exams (Written, Oral, etc.) |
1 |
10 |
10 |
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Final Exam |
1 |
15 |
15 |
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Total Workload: | 98 |
| Total Workload / 25 (h): | 3.92 |
| ECTS Credit: | 4 |
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