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Course Description Course Name : Endogenous active substances Course Code : FAR-516 Course Type : Compulsory Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall (16 Weeks) ECTS : 5 Name of Lecturer(s) : Prof.Dr. SERPİL ÖNDER Prof.Dr. NACİYE YAKTUBAY DÖNDAŞ Learning Outcomes of the Course : Describes and classifies endogenous active substances Explains the pharmacological effetcs and action mechanisms comments on the clinical indications, contraindications, adverse effects and drug interactions associated with endogenous active substances and their antagonists used for therapeutic purposes Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : to describe, to classify and to learn about the action mechanisms of endogenous active substances. Course Contents : Autacoids and their classifications; physiological significance of autocoids and their pharmacological effects, their agonists and antagonists used for therapeutic purposes Language of Instruction : Turkish Work Place : Seminar room   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Autacoids and Classification of Autacoids reads relevant books and reviews literature Presentation, interactive 2 Histamine and Histamine Receptors reads relevant books and reviews literature Presentation, interactive 3 Histamine receptor antagonists and their pharmacological effects reads relevant books and reviews literature Presentation, interactive 4 Serotonin, serotonin receptors and physiological importance of serotonin reads relevant books and reviews literature Presentation, interactive 5 Therapeutic used serotonin agonists and antagonists reads relevant books and reviews literature Presentation, interactive 6 Angiotensin, Angiotensin Receptors and Pharmacological Effects of Angiotensin, Angiotensin converting enzyme inhibitors and angiotensin receptor blockers reads relevant books and reviews literature Presentation, interactive 7 Endothelins, Kinins and Antagonist of Kinins reads relevant books and reviews literature Presentation, interactive 8 Midterm reads relevant books and reviews literature Written examination 9 Cyclooxygenase products reads relevant books and reviews literature Presentation, interactive 10 Leukotrienes and other lipoxygenase products reads relevant books and reviews literature Presentation, interactive 11 Drugs blocking eiconazoid synthesis and receptors reads relevant books and reviews literature Presentation, interactive 12 Cytochrome P450 products reads relevant books and reviews literature Presentation, interactive 13 The other products of arachidonic acid reads relevant books and reviews literature Presentation, interactive 14 Nitric oxide reads relevant books and reviews literature Presentation, interactive 15 The other Autocoids reads relevant books and reviews literature Presentation, interactive 16/17 Final Examination reads relevant books and reviews literature Written examination   Required Course Resources Resource Type Resource Name Recommended Course Material(s)    Katzung and Trevor’s Pharmacology  Goodman &Gilman´s The Pharmacological Basis of Therapeutics  Integrated Pharmacology  Netter´s IIlustrated Pharmacology Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 60     Homeworks/Projects/Others 2 40 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Students gain the ability to research on the areas like preventing irrational drug use detecting the problems due to drug use 4 2 Students gain basic pharmacological information 5 3 Students have the ability to take on the responsibilities of pharmacology 5 4 Students know the experimental research techniques in pharmacology 2 5 Students gain the ability to present their knowledge in an academic environment 5 6 Students have an ability to access scientific information 5 7 Students are informed about pharmacovigilance 3 8 Students have the ability to apply the basic principles of rational drug use on daily practice 5 9 Students gain the ability to take place in the in vitro/ in vivo animal experiments 4 10 Students gain the ability to plan and conduct experimental pharmacological projects and analyze the experimental results. 2 11 Students gain the ability to follow present literature in the field of pharmacology 5 12 Students guide the assistant health personnel to receive pharmacology education 3 13 Students are informed about rational drug use 4 14 Students know the pharmacological research areas 5 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 3 42     Out of Class Study (Preliminary Work, Practice) 14 3 42 Assesment Related Works     Homeworks, Projects, Others 2 10 20     Mid-term Exams (Written, Oral, etc.) 1 10 10     Final Exam 1 10 10 Total Workload: 124 Total Workload / 25 (h): 4.96 ECTS Credit: 5