| Course Description |
|
| Course Name |
: |
Experimental convulsion and depression models |
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| Course Code |
: |
FAR528 |
|
| Course Type |
: |
Optional |
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| Level of Course |
: |
Second Cycle |
|
| Year of Study |
: |
1 |
|
| Course Semester |
: |
Fall and Spring (16 Weeks) |
|
| ECTS |
: |
4 |
|
| Name of Lecturer(s) |
: |
Prof.Dr. FAZİLET AKSU
|
|
| Learning Outcomes of the Course |
: |
Knows the definition and mechanisms of depression
Learns the scientific and ethical rules of animal testing
Learns the experimental depression models and examines the effectiveness/clinical accordance of these models.
Learns the experimental convulsion models and examines the effectiveness/clinical accordance of these models.
Knows the statistical analysis of experimental convulsion and depression models.
|
|
| Mode of Delivery |
: |
Face-to-Face |
|
| Prerequisites and Co-Prerequisites |
: |
None |
|
| Recommended Optional Programme Components |
: |
None |
|
| Aim(s) of Course |
: |
To gain information about drugs used in depressive and convulsive diseases and the investigation of methods that create convulsion and depression in experiemental animals to develop new pharmacological treatment methods |
|
| Course Contents |
: |
Definition of depression, antidepressant drugs, convulsions, convulsion mechanisms, anticonvulsant drugs, experinemtal depression and convulsion models. |
|
| Language of Instruction |
: |
Turkish |
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| Work Place |
: |
Classroom and laboratory. |
|
|
Course Outline /Schedule (Weekly) Planned Learning Activities |
| Week | Subject | Student's Preliminary Work | Learning Activities and Teaching Methods |
|
1 |
Using experimental animals in pharmacological research, scientific and ethical rules. |
Suggested reading |
Power Point presentation |
|
2 |
Using experimental animals in pharmacological research, scientific and ethical rules. |
Suggested reading |
Power Point presentation |
|
3 |
Convulsive diseases and drugs used for treatment. |
Suggested reading |
Power Point presentation |
|
4 |
Experimental convulsion methods: Tests evaluating the efficacy of drugs against generalized tonic-clonic seizures. |
Suggested reading |
Power Point presentation, article review |
|
5 |
Experimental convulsion methods: Vocal stimulus tests against odiogenic seizures. |
Suggested reading |
Power Point presentation, article review |
|
6 |
Experimental convulsion methods: Tests that prevent generalized absence seizures. |
Suggested reading |
Power Point presentation, article review |
|
7 |
Experimental convulsion methods: Tests that evaluate the efficacy of drugs against focal seizures. |
Reading from suggested book and article. |
Power Point presentation, article review |
|
8 |
Midterm exam |
Preparation for exam |
Oral examination |
|
9 |
Evaluation of results in experimental convulsion methods and discussion of clinical accordance. |
Reading suggested articles. |
Power Point presentation, article review and discussion |
|
10 |
Depression: Definition and pharmacological approach |
Reading from suggested books |
Power Point presentation |
|
11 |
Experimental depression models: Chemical tests |
Önerilen kitap ve makale okuma |
Power Point presentation, article review |
|
12 |
Experimental depression models: Learned helpnessless, forced swimming and tail suspension tests |
Reading from suggested book and article. |
Power Point presentation, article review |
|
13 |
Experimental depression models: Chronic unpredictible mild stress |
Reading from suggested book and article. |
Power Point presentation, article review |
|
14 |
Experimental depression models: Social stress model. Evaluation of results in experimental convulsion methods and discussion of clinical accordance. |
Reading from suggested book and article. |
Power Point presentation, article review |
|
15 |
Statistical analysis in convulsion and depression experiments |
Evaluation of suggested articles |
Power Point presentation, article review |
|
16/17 |
Final exam |
Preparation for exam |
Oral exam, participation to lessons and discussion, preparation of homework |
|
|
| Contribution of the Course to Key Learning Outcomes |
| # | Key Learning Outcome | Contribution* |
|
1 |
Students gain the ability to research on the areas like preventing irrational drug use detecting the problems due to drug use |
5 |
|
2 |
Students gain basic pharmacological information |
4 |
|
3 |
Students have the ability to take on the responsibilities of pharmacology |
5 |
|
4 |
Students know the experimental research techniques in pharmacology |
5 |
|
5 |
Students gain the ability to present their knowledge in an academic environment |
5 |
|
6 |
Students have an ability to access scientific information |
5 |
|
7 |
Students are informed about pharmacovigilance |
3 |
|
8 |
Students have the ability to apply the basic principles of rational drug use on daily practice |
3 |
|
9 |
Students gain the ability to take place in the in vitro/ in vivo animal experiments |
5 |
|
10 |
Students gain the ability to plan and conduct experimental pharmacological projects and analyze the experimental results. |
5 |
|
11 |
Students gain the ability to follow present literature in the field of pharmacology |
5 |
|
12 |
Students guide the assistant health personnel to receive pharmacology education |
3 |
|
13 |
Students are informed about rational drug use |
3 |
|
14 |
Students know the pharmacological research areas |
5 |
| * Contribution levels are between 0 (not) and 5 (maximum). |
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