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Course Description Course Name : FREE RADICALS AND ANTIOXYDANT SYSTEM IN BIOCHEMISTRY Course Code : BİK-530 Course Type : Optional Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall and Spring (16 Weeks) ECTS : 4 Name of Lecturer(s) : Prof.Dr. ABDULLAH TULİ Prof.Dr. LEVENT KAYRIN Learning Outcomes of the Course : describes the term of free radicals knows oxygene radicals and formation process of radicals derived from oxygenes gives information about free radical species explains protection systems against oxydants in biological systems explains superoxide theory describes lipid peroxidation gives information about the molecules taking part in the protection from free radicals destruction knows the effects of free radicals on causing diseases implements the methods for analysing markers which gives information about free radicals and anti-oxydant system Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : the aim of this course is to teach students the definition of free radicals, oxygen and oxygen derived radicals, classification of free radicals, protection against the free radicals in biological systems, superoxide theory, lipid peroxidation, free radicals and diseases. Course Contents : this course includes the definition of free radicals, oxygen and oxygen derived radicals, classification of free radicals, protection against the free radicals in biological systems, superoxide theory, lipid peroxidation, free radicals and diseases. Language of Instruction : Turkish Work Place : Medical Faculty, Seminar Hall of Biochemistry Department   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 definition of free radicals reading suggested sources interactive study 2 reactive oxygen radicals reading suggested sources interactive study 3 biological sources of free radicals reading suggested sources interactive study 4 formation of free radicals in cell reading suggested sources interactive study 5 formation of free radicals in cell reading suggested sources interactive study 6 cell based immune system against free radical reactions reading suggested sources interactive study 7 anti-oxydant compounds reading suggested sources interactive study 8 mid-term examination revision of previous lessons classic exam 9 anti-oxydant enzymes reading suggested sources interactive study 10 roles of free radicals in some diseases reading suggested sources interactive study 11 roles of free radicals in geriatry reading suggested sources interactive study 12 nutrition and anti-oxydant system reading suggested sources interactive study 13 sports and anti-oxydant system reading suggested sources interactive study 14 usage of anti-oxydants in treatment reading suggested sources interactive study 15 general assesment reading suggested sources interactive study 16/17 Final examination revision of previous lessons classic exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Sami Ahmad. Oxidative Stress and Antioxidant Defenses in Biology. Chapman & Hall, 1995.  Barry Halliwell, John MC Gutteridge. Free Radicals in Biology and Medicine. Third Ed., Oxford, 2000. Required Course Material(s)   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 60     Homeworks/Projects/Others 1 40 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Applies innovations in laboratory processes by doing research. 2 2 Comprehends the interaction of biochemistry with the other scientific fields. 1 3 Knows experimental methods in biochemistry. 1 4 Takes part in in-vitro/in-vivo animal research studies. 0 5 Carries out studies in the field of biochemistry as a member of a team. 1 6 Gains ongoing professional skills. 1 7 Comprehends basic information about the field of biochemistry. 3 8 Interprets the factors and phases that effect the laboratory results. 2 9 Uses laboratory tools. 2 10 Knows the ethical and legal characteristics of laboratory processes, and interpretes economical value of these processes for the country. 0 11 Supports a scientific research. 1 12 Interpretes scientific research results which are carried out. 1 13 Generates a report from the conclusion of the scientific research. 2 14 Knows biochemical sampling rules. 1 15 Studies and makes research in laboratory settings. 1 16 Corporates with the other members of the team in an efficient, sensitive and respectfull way. 2 17 Interpretes and corrolates biochemical data and theoretical concept. 1 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 2 28     Out of Class Study (Preliminary Work, Practice) 14 2 28 Assesment Related Works     Homeworks, Projects, Others 1 10 10     Mid-term Exams (Written, Oral, etc.) 1 10 10     Final Exam 1 20 20 Total Workload: 96 Total Workload / 25 (h): 3.84 ECTS Credit: 4