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| Course Description |
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| Course Name |
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BASIC BIOCHEMISTRY II |
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| Course Code |
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BİK-502 |
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| Course Type |
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Compulsory |
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| Level of Course |
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Second Cycle |
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| Year of Study |
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1 |
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| Course Semester |
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Spring (16 Weeks) |
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| ECTS |
: |
7 |
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| Name of Lecturer(s) |
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Prof.Dr. ABDULLAH TULİ
Prof.Dr. LEVENT KAYRIN
Prof.Dr. KIYMET AKSOY
Prof.Dr. NURTEN DİKMEN
Prof.Dr. MEHMET AKİF ÇÜRÜK
Assoc.Prof.Dr. TAMER C. İNAL
Asst.Prof.Dr. ÖZLEM GÖRÜROĞLU ÖZTÜRK
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| Learning Outcomes of the Course |
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Student who successfully completes this course has general knowledge about; replication, transcription, translation, genetic code, genetic control
learns general description of hormones their effect mechanism. hormones of hypothalamus and hypophisis. adrenal hormones and their biochemistry, thyroid hormones and their biochemistry. parathyroid hormones. sex hormones. gastro-intestinal system hormones. other hormone-like compounds. pancreas hormones.
owns a general view to carbohydrate metabolism, digestion and absorbtion of carbohydrates, interaction of organs in carbohydrate metabolism. regulation of blood glucose.
learns digestion and absorbtion of lipids, general view to lipid metabolism. metabolism of lipoproteins
learns metabolism of amino acids, synthesis of urea, metabolism of specific amino acids. cholesterol metabolism.
learns digestion and absorbtion of proteins, synthesis and catabolism of purine and primidine bases. blood gases, acide-base equilibrium. urine analysis. biochemistry of nutrition. blood and blood biochemistry.
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| Mode of Delivery |
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Face-to-Face |
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| Prerequisites and Co-Prerequisites |
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BİK-501 BASIC BIOCHEMISTRY I
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| Recommended Optional Programme Components |
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None |
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| Aim(s) of Course |
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The aim of this course is to enable students gain general knowledge about the metabolism |
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| Course Contents |
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Replication, transcription. Translation, genetic code, genetic control. General discription of hormones and their mechanisms. the hormones of hypothalamus and hypophysis. Adrenal hormones and the biochemistry of adrenal hormones. thyroid hormones and their biochemistry. sex hormones. the hormones of gastro-intestinal systems. Other hormone-like compounds. pancreatic hormones. General view to carbohydrate metabolism. Digestion and absorbtion of carbohdrates. Interaction of organs in carbohdrate metabolism. Regulation of blood glucose. Digestion and absorbtion of lipids. General view to lipid metabolism. Metabolism of lipoproteins. Metabolism of aminoacids synthesis of urea. Metabolism of special aminoacids. metabolism of cholesterol. Digestion and absorbtion proteins. Synthesis and catabolism of purine and primidine bases. Blood gases, equilibrium of acides and bases. urine analysis. Biochemistry of nutrition. Blood and blood biochemistry. |
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| Language of Instruction |
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Turkish |
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| Work Place |
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Medical Faculty, Seminar Hall of Biochemistry Department |
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Course Outline /Schedule (Weekly) Planned Learning Activities |
| Week | Subject | Student's Preliminary Work | Learning Activities and Teaching Methods |
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1 |
Digestion and Absorbtion of Lipids
Metabolism of Fatty Acids (Oxidation- Biosynthesis) |
text to be read,web survey, presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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2 |
Metabolism of Cholesterol
Metabolism of Triglyseriides, Phopholipids, Syphingolipids
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text to be read,web survey, presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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3 |
Metabolism of Lipoproteins,
Digestion and Absorbtion of Proteins, Meister Cycle |
text to be read,web survey , presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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4 |
Metabolism of Amino Acids,
Defects of Amino Acid Metabolism |
text to be read, web survey , presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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5 |
Biochemistry of Hemostasis |
text to be read,web survey, presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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6 |
Mid-term examination |
revision of courses |
classic question-answer exam |
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7 |
Plasma Proteins, Plasma Enzymes |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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8 |
Organisation of DNA and RNA |
text to be read, web survey , presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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9 |
Replication and Repair Mechanisms,
Transcription and Splicing |
text to be read,web survey , presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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10 |
Translation and Post-translational Modifications,
Purine and Pyrimidine Metabolisms |
text to be read,web survey , presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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11 |
Metabolism of Xenobiotics,
Effect Mechanisms of Hormones |
text to be read,web survey, presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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12 |
Hormones of Hypotalamus and Pituitary Gland,
Hormones of Pancreas and Gastro-Intestinal System |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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13 |
Thyroid hormones,
Hormones that involve in Regulation of Ca and P |
text to be read, web survey, presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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14 |
Hormones that involve in Regulation of Ca and P,
Leptin and Leptin-Related Hormones |
text to be read, web survey, presentations, assignment, sample questions |
lecturing , illustrations, group discussions, brain storming, seminar |
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15 |
Hormones of Adrenal Gland,
Sex hormones |
text to be read,web survey, presentations, assignment, sample questions |
lecturing, illustrations, group discussions, brain storming, seminar |
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16/17 |
Final Examination |
revision of courses |
classic question-answer exam |
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Required Course Resources |
| Resource Type | Resource Name |
| Recommended Course Material(s) |
 Murray RK, Bender DA, Botham KM, Kennelly PJ, Rodwell VW, Weil PA. Harper’s Illustrated Biochemistry, 29th Ed., Mc Graw Hill and Lange, 2012.
Boynes JW, Dominiczak MH. Medical Biochemistry, 3rd Ed., Mosby Elsevier, 2009.
Nelson DL, Cox MM. Lehninger Principles of Biochemistry, 6th Ed., W. H. Freeman and Company, 2013.
Mathews CK, van Holde KE. Biochemistry, The Benjamin/Cumming Pub, 1990.
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| Required Course Material(s) | |
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Assessment Methods and Assessment Criteria |
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Semester/Year Assessments |
Number |
Contribution Percentage |
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Mid-term Exams (Written, Oral, etc.) |
1 |
80 |
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Homeworks/Projects/Others |
3 |
20 |
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Total |
100 |
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Rate of Semester/Year Assessments to Success |
40 |
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Final Assessments
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100 |
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Rate of Final Assessments to Success
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60 |
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Total |
100 |
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| Contribution of the Course to Key Learning Outcomes |
| # | Key Learning Outcome | Contribution* |
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1 |
Applies innovations in laboratory processes by doing research. |
1 |
|
2 |
Comprehends the interaction of biochemistry with the other scientific fields. |
4 |
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3 |
Knows experimental methods in biochemistry. |
2 |
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4 |
Takes part in in-vitro/in-vivo animal research studies. |
0 |
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5 |
Carries out studies in the field of biochemistry as a member of a team. |
0 |
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6 |
Gains ongoing professional skills. |
5 |
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7 |
Comprehends basic information about the field of biochemistry. |
5 |
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8 |
Interprets the factors and phases that effect the laboratory results. |
3 |
|
9 |
Uses laboratory tools. |
0 |
|
10 |
Knows the ethical and legal characteristics of laboratory processes, and interpretes economical value of these processes for the country. |
1 |
|
11 |
Supports a scientific research. |
0 |
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12 |
Interpretes scientific research results which are carried out. |
4 |
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13 |
Generates a report from the conclusion of the scientific research. |
3 |
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14 |
Knows biochemical sampling rules. |
0 |
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15 |
Studies and makes research in laboratory settings. |
0 |
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16 |
Corporates with the other members of the team in an efficient, sensitive and respectfull way. |
0 |
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17 |
Interpretes and corrolates biochemical data and theoretical concept. |
0 |
| * Contribution levels are between 0 (not) and 5 (maximum). |
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| Student Workload - ECTS |
| Works | Number | Time (Hour) | Total Workload (Hour) |
| Course Related Works |
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Class Time (Exam weeks are excluded) |
14 |
4 |
56 |
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Out of Class Study (Preliminary Work, Practice) |
14 |
4 |
56 |
| Assesment Related Works |
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Homeworks, Projects, Others |
3 |
7 |
21 |
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Mid-term Exams (Written, Oral, etc.) |
1 |
10 |
10 |
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Final Exam |
1 |
20 |
20 |
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Total Workload: | 163 |
| Total Workload / 25 (h): | 6.52 |
| ECTS Credit: | 7 |
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