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  Course Description
Course Name : Lineer Models

Course Code : BİS531

Course Type : Optional

Level of Course : Second Cycle

Year of Study : 1

Course Semester : Spring (16 Weeks)

ECTS : 6

Name of Lecturer(s) : Prof.Dr. HÜSEYİN REFİK BURGUT

Learning Outcomes of the Course : Linear models for binary and count data ; Logistic, Poisson, Log Linear
ANOVA-ANCOVA- fixed and random effect linear models for continuous data
Generalized linear models for categorical data
Mixed linear models for continually continuous data
Linear models for repeated continuous data

Mode of Delivery : Face-to-Face

Prerequisites and Co-Prerequisites : BİS540 Applied Biostatistics

Recommended Optional Programme Components : None

Aim(s) of Course : To know the various linear models to analyze data obtained from the epidemiological and clinical studies, to determine the appropriate one related to the properties of data, to interpret the results of the application

Course Contents : Linear models and data sets, classical linear models;regression, anova and ancova, generalized linear models, link functions,: multiple regression, linear regression models for longitidunal data, poisson regression, marginal and transitional models, competing risk models

Language of Instruction : Turkish+English

Work Place : Informatic lab in Biostatistics Dept.


  Course Outline /Schedule (Weekly) Planned Learning Activities
Week Subject Student's Preliminary Work Learning Activities and Teaching Methods
1 WHY USE MODELING IN DATA ANALYSIS? Basic terminalogies reading the first chapters in reference book #1 reading
2 Data sets to be used as an example in linear modeling: REFUGEE CHILDREN GROWTH, MOTHER STRESS- CHILDREN MORBIDITY, NUMBER OF SEXUAL PARTNERS CHANGİNG reading the related chapters in reference boks #2 and #3 reading and assignment
3 CLASSICAL LINEAR MODELS; REGRESSION, ANOVA AND ANCOVA reading the related chapters in reference boks #2 and #3 reading and assignment
4 GENERALIZED LINEAR MODELS;RANDOM COMPONENT, SYSTEMATIC COMPONENET, EXPONENETIAL DISPERTION FAMILY, LINK FUNCTION reading the related chapters in reference boks #2 and #3 reading and assignment
5 SPECIAL CASES; MULTIPLE REGRESSION, LOGISTIC REGRESSION POISSON REGRESSION reading the related chapters in reference boks #2 and #3 reading and assignment
6 LIKELIHOODS, MARGINAL, PARTIAL PSAUDO VE QUASI LIKELIHOOD reading the related chapters in reference boks #2 and #3 reading and assignment
7 LONGITUDINAL DATA AND EXAMPLE-LINEAR MODELS reading the related chapters in reference boks #2 and #3 reading and assignment
8 MID TERM EXAM reading the related chapters in reference boks #2 and #3 reading and assignment
9 MARGINAL MODELS-TRANSITIONAL MODEL reading the related chapters in reference boks #2 and #3 reading and assignment
10 RANDOM EFFECT MODELS reading the related chapters in reference boks #2 and #3 reading and assignment
11 INFERENCE USING GENERALIZED ESTIMATION EQUATION (GEE) reading the related chapters in reference boks #2 and #3 reading and assignment
12 MODELS FOR TIME TO EVENT DATA reading the related chapters in reference boks #2 and #3 reading and assignment
13 REPEATED TIME TO EVENT DATA- ANDERSON AND GILLS MODELS, MARGINAL MODELS, FRAİLTY MODELS reading the related chapters in reference boks #2 and #3 reading and assignment
14 COMPETING RISK MODELS reading the related chapters in reference boks #2 and #3 reading and assignment
15 ADDITIVE MODELS reading the related chapters in reference boks #2 and #3 reading and assignment
16/17 FINAL EXAM


  Required Course Resources
Resource Type Resource Name
Recommended Course Material(s)  
 
 
Required Course Material(s)


  Assessment Methods and Assessment Criteria
Semester/Year Assessments Number Contribution Percentage
    Mid-term Exams (Written, Oral, etc.) 1 50
    Homeworks/Projects/Others 14 50
Total 100
Rate of Semester/Year Assessments to Success 40
 
Final Assessments 100
Rate of Final Assessments to Success 60
Total 100

  Contribution of the Course to Key Learning Outcomes
# Key Learning Outcome Contribution*
1 Students design scientific research studies in order to give response to the problem arising from health and clinical sciences 0
2 Students provide consulting services by using effective communication skills; take part in research teamworks; defend the ethical rules. 0
3 Students collect data from research studies, analyze, and make inferences 4
4 Students design health survey, determine the sampling method and conduct the survey 0
5 Students knows the system of international classification of diseases, obtain and analyze hospital statistics. 0
6 Students select the appropriate statistical procedure for analysis , apply and make inferences. 4
7 Students use the necessary statistical packages for analysis, if necessary write and develop software. 4
8 Students select and use proper statistical procedure for diagnosis and in making inferences for the data in health and clinical medicine and provide consultance to clinicians in the field. 0
9 Students comprehends the fundamentals of statistical theory related to the field of health ( probability and bayesian biostatistics). 0
10 Students explain demographic terminologies and statistical methods in the field of health sciences. 0
11 Students understand and use medical terminology. 0
12 Students develop the ability of critical thinking, make a conclusion with a critical approach to the evidence 0
13 Students apply analytical procedure to frequently used survival data, multivariate procedure and regression techniques. 0
14 Students follow the latest development in medical informatics and employ frequently used tools and methods. 0
15 Students explain the fundamental terminologies in epidemiology, guide researchers conducting field survey and clinical studies, develop methodologies in determining disease risk factor and disease burden and advise for choosing proper diagnostic test. 0
* Contribution levels are between 0 (not) and 5 (maximum).

  Student Workload - ECTS
Works Number Time (Hour) Total Workload (Hour)
Course Related Works
    Class Time (Exam weeks are excluded) 14 3 42
    Out of Class Study (Preliminary Work, Practice) 14 3 42
Assesment Related Works
    Homeworks, Projects, Others 14 4 56
    Mid-term Exams (Written, Oral, etc.) 1 3 3
    Final Exam 1 12 12
Total Workload: 155
Total Workload / 25 (h): 6.2
ECTS Credit: 6