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Course Description Course Name : Special Bacteriology II Course Code : MİK-506 Course Type : Optional Level of Course : Second Cycle Year of Study : 1 Course Semester : Fall and Spring (16 Weeks) ECTS : 4 Name of Lecturer(s) : Prof.Dr. FATİH KÖKSAL Learning Outcomes of the Course : Describes the general characteristics of Mycobacteria, Corynebacteria, Bacillus species, Leptospira, Borrelia, Treponema, Mycoplasma, ureoplasma, Chlamydia, small gram-negative bacilli and anaerobic bacteria, causing infectious disease. Identifies the source and mode of transmission in bacteria causing infectious disease. Lists the mechanisms of antimicrobial resistance bacteria causing infectious disease. Applies and interprets antimicrobial susceptibility testing. Explains the bacterial toxins and mechanisms of disease. Lists the methods of bacteria isolation from clinical samples, causing infectious disease Lists the molecular methods for the diagnosis of bacterial infections. Mode of Delivery : Face-to-Face Prerequisites and Co-Prerequisites : None Recommended Optional Programme Components : None Aim(s) of Course : Acquires basic knowledge about the properties of the bacteria that cause disease in humans, their diseases, antimicrobial resistance mechanisms and diagnosis. Course Contents : In this course, agents of disease in humans-Mycobacteria, Corynebakteria, Bacillus species, Leptospira, Borrelia, Treponema, Mycoplasma, Ureoplasma, Chlamydia, small gram-negative bacilli and anaerobic bacteria-are introduced. Students learn their general characteristics, diseases they cause, their antimicrobial resistance mechanisms and diagnosis. Language of Instruction : Turkish Work Place : C.U Faculty of Medicine Department of Medical Microbiology convention hall and laboratories.   Course Outline /Schedule (Weekly) Planned Learning Activities Week Subject Student's Preliminary Work Learning Activities and Teaching Methods 1 Mycobacteria Self-study, Reading recommended resources Verbal lecture, presentation, discussion 2 Mycobacterium tuberculosis Self-study, Reading recommended resources Verbal lecture, presentation, discussion 3 Corynebacteria Self-study, Reading recommended resources Verbal lecture, presentation, discussion 4 Bacillus species Self-study, Reading recommended resources Verbal lecture, presentation, discussion 5 Leptospira Self-study, Reading recommended resources Verbal lecture, presentation, discussion 6 Borrelia, Treponema Self-study, Reading recommended resources Verbal lecture, presentation, discussion 7 Mycoplasma and ureoplasma Self-study, Reading recommended resources Verbal lecture, presentation, discussion 8 Midterm Exam Exam Preparation Written Exam 9 Chlamydia Self-study, Reading recommended resources Verbal lecture, presentation, discussion 10 Small gram-negative bacilli: Brucella, Bordetella, Haemophilus Self-study, Reading recommended resources Verbal lecture, presentation, discussion 11 General characteristics of anaerobic bacteria: Clostridium, Bacteroides Self-study, Reading recommended resources Verbal lecture, presentation, discussion 12 Mechanisms of antimicrobial resistance in bacteria Self-study, Reading recommended resources, Collection of new information from the web Verbal lecture, presentation, discussion, group work 13 Antimicrobial susceptibility tests Self-study, Reading recommended resources, Collection of new information from the web Verbal lecture, presentation, discussion, group work, Laboratory 14 Bacterial toxins and their disease mechanisms Self-study, Reading recommended resources, Collection of new information from the web Verbal lecture, presentation, discussion, group work 15 Molecular methods in the diagnosis of bacterial infections Self-study, Reading recommended resources Verbal lecture, presentation, discussion 16/17 Final Exam Exam Preparation Written Exam   Required Course Resources Resource Type Resource Name Recommended Course Material(s)  Lecture notes and slides  Human Microbiology (Lifelines).P.H.Simon Taylo& Francis 2002  Temel ve Klinik Mikrobiyoloji, Şemsettin Ustaçelebi. Güneş Kitabevi Required Course Material(s)   Essential Microbiolgy S.Hogg J.Willey& Sons 2005.  Basic Lab Clinical Bacteriology. 2. BASKI J.Vandepıtte WHO 2003  Bacterial Pathogenesis: a Molecular Approach, Second Edition, Abigail A. Salyers and Dixie D. Whitt. 2001, ASM Press.   Assessment Methods and Assessment Criteria Semester/Year Assessments Number Contribution Percentage     Mid-term Exams (Written, Oral, etc.) 1 60     Homeworks/Projects/Others 2 40 Total 100 Rate of Semester/Year Assessments to Success 40   Final Assessments 100 Rate of Final Assessments to Success 60 Total 100   Contribution of the Course to Key Learning Outcomes # Key Learning Outcome Contribution* 1 Identifies morphological and physiological characteristics of microorganisms 5 2 Identificates genomic structures of microorganisms 5 3 Explains microorganisms virulance factors and infection mechanisms. 5 4 Defines the mechanisms of immune response and defense against microorganisms 5 5 Lists the antimicrobial agents. 5 6 Defines the mechanisms of resistance development against antimicrobial agents. 5 7 Lists the microscopy, culture, serological and molecular diagnostic principles used in the laboratory diagnosis of infectious microorganisms. 5 8 Lists microbiological tests for identification of microorganisms 5 9 Implements and applies the methods used in the period from receipt of the clinical specimens up to identification of the causative agent . 3 10 Prepares a suitable media, applicates the staining methods, biochemical tests and molecular diagnostic methods to identify microorganisms from clinical samples. 3 11 Applies the biochemical tests and basic microbiological staining methods which are necessary for microbiological identification . 3 12 Determines the microorganisms by using basic molecular diagnostic techniques. 3 13 Works individually or as a team member related to the field. 1 14 Carries out the missions given within the scope of research projects. 1 15 Develops a positive attitude and behaviour towards lifelong learning. 1 16 Evaluates own knowledge and new-learned knowledge in a critical view after graduating. 1 17 Communicates effectively. 1 18 Transfers their own ideas and developments in the field, and offers solutions visually and verbally supporting with qualitative and quantitative data. 1 19 Applies ethical principles during study, evaluation and result sharing. 1 * Contribution levels are between 0 (not) and 5 (maximum).   Student Workload - ECTS Works Number Time (Hour) Total Workload (Hour) Course Related Works     Class Time (Exam weeks are excluded) 14 3 42     Out of Class Study (Preliminary Work, Practice) 14 3 42 Assesment Related Works     Homeworks, Projects, Others 2 3 6     Mid-term Exams (Written, Oral, etc.) 1 10 10     Final Exam 1 10 10 Total Workload: 110 Total Workload / 25 (h): 4.4 ECTS Credit: 4